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Optimizing the Cell Painting assay for image-based profiling 优化基于图像的分析的细胞绘画分析 Cimini, Beth A.; Chandrasekaran, Srinivas Niranj; Kost-Alimova, Maria; Miller, Lisa; Goodale, Amy; Fritchman, Briana; Byrne, Patrick; Garg, Sakshi; Jamali, Nasim; Logan, David J.; Concannon, John B.; Lardeau, Charles-Hugues; Mouchet, Elizabeth; Singh, Shantanu; Abbasi, Hamdah Shafqat; Aspesi, Jr Peter; Boyd, Justin D.; Gilbert, Tamara; Gnutt, David; Hariharan, Santosh; Hernandez, Desiree; Hormel, Gisela; Juhani, Karolina; Melanson, Michelle; Mervin, Lewis H.; Monteverde, Tiziana; Pilling, James E.; Skepner, Adam; Swalley, Susanne E.; Vrcic, Anita; Weisbart, Erin; Williams, Guy; Yu, Shan; Zapiec, Bolek; Carpenter, Anne E. 分享 收藏
Leveraging Cell Painting Images to Expand the Applicability Domain and Actively Improve Deep Learning Quantitative Structure-Activity Relationship Models Herman, Dorota; Kandula, Maciej M. M.; Freitas, Lorena G. A.; van Dongen, Caressa; Van, Thanh Le; Mesens, Natalie; Jaensch, Steffen; Gustin, Emmanuel; Micholt, Liesbeth; Lardeau, Charles-Hugues; Varsakelis, Christos; Reumers, Joke; Zoffmann, Sannah; Will, Yvonne; Peeters, Pieter J. J.; Ceulemans, Hugo 分享 收藏
Molecular and Pharmacological Bladder Cancer Therapy Screening: Discovery of Clofarabine as a Highly Active Compound Ertl, Iris E.; Lemberger, Ursula; Ilijazi, Dafina; Hassler, Melanie R.; Bruchbacher, Andreas; Brettner, Robert; Kronabitter, Hannah; Gutmann, Michael; Vician, Petra; Zeitler, Gerhard; Koren, Anna; Lardeau, Charles-Hugues; Mohr, Thomas; Haitel, Andrea; Comperat, Eva; Oszwald, Andre; Wasinger, Gabriel; Clozel, Thomas; Elemento, Olivier; Kubicek, Stefan; Berger, Walter; Shariat, Shahrokh F. 分享 收藏
An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation Casteels, Tamara; Zhang, Yufeng; Frogne, Thomas; Sturtzel, Caterina; Lardeau, Charles-Hugues; Sen, Ilke; Liu, Xiaocheng; Hong, Shangyu; Pauler, Florian M.; Penz, Thomas; Brandstetter, Marlene; Barbieux, Charlotte; Berishvili, Ekaterine; Heuser, Thomas; Bock, Christoph; Riedel, Christian G.; Meyer, Dirk; Distel, Martin; Hecksher-Sorensen, Jacob; Li, Jin; Kubicek, Stefan 分享 收藏
A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs Girardi, Enrico; Cesar-Razquin, Adrian; Lindinger, Sabrina; Papakostas, Konstantinos; Konecka, Justyna; Hemmerich, Jennifer; Kickinger, Stefanie; Kartnig, Felix; Guertl, Bettina; Klavins, Kristaps; Sedlyarov, Vitaly; Ingles-Prieto, Alvaro; Fiume, Giuseppe; Koren, Anna; Lardeau, Charles-Hugues; Kandasamy, Richard Kumaran; Kubicek, Stefan; Ecker, Gerhard F.; Superti-Furga, Giulio 分享 收藏
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Mapping the Human Kinome in Response to DNA Damage Owusu, Michel; Bannauer, Peter; da Silva, Joana Ferreira; Mourikis, Thanos P.; Jones, Alistair; Majek, Peter; Caldera, Michael; Wiedner, Marc; Lardeau, Charles-Hugues; Mueller, Andre C.; Menche, Joerg; Kubicek, Stefan; Ciccarelli, Francesca D.; Loizou, Joanna I. 分享 收藏
Pharmacologic inhibition of STAT5 in acute myeloid leukemia 急性髓系白血病中STAT5的药理抑制 Wingelhofer, Bettina; Maurer, Barbara; Heyes, Elizabeth C.; Cumaraswamy, Abbarna A.; Berger-Becvar, Angelika; de Araujo, Elvin D.; Orlova, Anna; Freund, Patricia; Ruge, Frank; Park, Jisung; Tin, Gary; Ahmar, Siawash; Lardeau, Charles-Hugues; Sadovnik, Irina; Bajusz, David; Keseru, Gyorgy Miklos; Grebien, Florian; Kubicek, Stefan; Valent, Peter; Gunning, Patrick T.; Moriggl, Richard 分享 收藏
Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH Mazouzi, Abdelghani; Battistini, Federica; Moser, Sarah C.; da Silva, Joana Ferreira; Wiedner, Marc; Owusu, Michel; Lardeau, Charles-Hugues; Ringler, Anna; Weil, Beatrix; Neesen, Juergen; Orozco, Modesto; Kubicek, Stefan; Loizou, Joanna I. 分享 收藏
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor Licciardello, Marco P.; Ringler, Anna; Markt, Patrick; Klepsch, Freya; Lardeau, Charles-Hugues; Sdelci, Sara; Schirghuber, Erika; Mueller, Andre C.; Caldera, Michael; Wagner, Anja; Herzog, Rebecca; Penz, Thomas; Schuster, Michael; Boidol, Bernd; Duernberger, Gerhard; Folkvaljon, Yasin; Stattin, Par; Ivanov, Vladimir; Colinge, Jacques; Bock, Christoph; Kratochwill, Klaus; Menche, Joerg; Bennett, Keiryn L.; Kubicek, Stefan 分享 收藏
Global survey of the immunomodulatory potential of common drugs Vladimer, Gregory I.; Snijder, Berend; Krall, Nikolaus; Bigenzahn, Johannes W.; Huber, Kilian V. M.; Lardeau, Charles-Hugues; Sanjiv, Kumar; Ringler, Anna; Berglund, Ulrika Warpman; Sabler, Monika; de la Fuente, Oscar Lopez; Knoebl, Paul; Kubicek, Stefan; Helleday, Thomas; Jaeger, Ulrich; Superti-Furga, Giulio 分享 收藏
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions Martins, Rui; Maier, Julia; Gorki, Anna-Dorothea; Huber, Kilian V. M.; Sharif, Omar; Starkl, Philipp; Saluzzo, Simona; Quattrone, Federica; Gawish, Riem; Lakovits, Karin; Aichinger, Michael C.; Radic-Sarikas, Branka; Lardeau, Charles-Hugues; Hladik, Anastasiya; Korosec, Ana; Brown, Markus; Vaahtomeri, Kari; Duggan, Michelle; Kerjaschki, Dontscho; Esterbauer, Harald; Colinge, Jacques; Eisenbarth, Stephanie C.; Decker, Thomas; Bennett, Keiryn L.; Kubicek, Stefan; Sixt, Michael; Superti-Furga, Giulio; Knapp, Sylvia 分享 收藏
Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk Sdelci, Sara; Lardeau, Charles-Hugues; Tallant, Cynthia; Klepsch, Freya; Klaiber, Bjoern; Bennett, James; Rathert, Philipp; Schuster, Michael; Penz, Thomas; Fedorov, Oleg; Superti-Furga, Giulio; Bock, Christoph; Zuber, Johannes; Huber, Kilian V. M.; Knapp, Stefan; Muller, Susanne; Kubicek, Stefan 分享 收藏
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