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C

Christoph Bock

cemm research center for molecular medicine of the austrian academy of sciences
H指数:107
被引数:4.5万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Uncovering the transcriptional hallmarks of endothelial cell aging via integrated single-cell analysis

通过整合单细胞分析揭示内皮细胞衰老的转录特征

Nature Aging
IF19.4
2026-10-230
OAAI
Sarah Dobner; Lisa Kleissl; Fanni Tóth; Robert L. Paxton; Irena Yordanova; Kveta Brazdilova; Cedric Vanluyten; Aleksandra Aizenshtadt; Hanna Tóth; Jake Burton; Aglaja Kopf; Vera Belyaeva; Katharina Ferencevic; Dunja A. Al-Nuaimi; Mauriz A. Lichtenstein; Georg E. Winter; André F. Rendeiro; Christoph Bock; Joanna Kalucka; Stefan Krauss; Selma Osmanagic-Myers; Laurens J. Ceulemans; Georg Stary; Abdel Rahman Abdel Fattah; Laura P. M. H. de Rooij
Immune remodelling and molecular profiling of progressive brain metastases following cranial radiotherapy

颅脑放射治疗后进展性脑转移瘤的免疫重塑与分子特征分析

European Journal of Cancer
IF7.1
2026-08-010
PRE
Steindl, Ariane; Starzer, Angelika M.; Tomasich, Erwin; Kleinberger, Markus; Berchtold, Luzia; Eckert, Franziska; Widhalm, Georg; Gatterbauer, Brigitte; Hainfellner, Johannes A.; Wozelka-Oltjan, Lisa; Erguener, Bekir; Schuster, Michael; Bock, Christoph; Heller, Gerwin; Preusser, Matthias; Berghoff, Anna. S.
Cortical development dynamics across autism spectrum disorder mouse models

自闭症谱系障碍小鼠模型中的皮质发育动力学

Nature
IF48.5
2026-06-170
OAAI
Lena A. Schwarz; Christoph P. Dotter; Sergey Isaev; Michela Lisi; Daniel Malzl; Christoph Büschl; Sabrina Ladstätter; Bárbara Oliveira; Matteo Barel; Bernadette Basilico; Chaitanya Chintaluri; Sarah Gorkiewicz; Mohammad Goudarzi; Tereza Belinova; Stephan Reichl; Gintarė Sendžikaitė; Satish Arcot Jayaram; Peter Koppensteiner; Christoph Sommer; Tim P. Vogels; Jörg Menche; Igor Adameyko; Peter V. Kharchenko; Christoph Bock; Gaia Novarino
Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard

Pipeline Olympics：针对DNA甲基化测序数据，基于实验金标准的可延续性计算工作流基准测试

NUCLEIC ACIDS RESEARCH
IF13.1
2025-10-280
OAAI
Lin, Yu-Yu; Breuer, Kersten; Weichenhan, Dieter; Lafrenz, Pascal; Sarnataro, Antonella; Wilk, Agata; Chepeleva, Maryna; Mucke, Oliver; Schonung, Maximilian; Petermann, Franziska; Kensche, Philip Reiner; Weiser, Lena; Thommen, Frank; Giacomelli, Gideon; Nordstroem, Karl; Gonzalez-Avalos, Edahi; Merkel, Angelika; Kretzmer, Helene; Fischer, Jonas; Kramer, Stephen; Iskar, Murat; Wolf, Stephan; Buchhalter, Ivo; Esteller, Manel; Lawerenz, Christian; Twardziok, Sven; Zapatka, Marc; Hovestadt, Volker; Schlesner, Matthias; Schulz, Marcel H.; Hoffmann, Steve; Gerhauser, Clarissa; Walter, Jorn; Hartmann, Mark; Lipka, Daniel B.; Assenov, Yassen; Bock, Christoph; Plass, Christoph; Toth, Reka; Lutsik, Pavlo
Systematic discovery of CRISPR-boosted CAR T cell immunotherapies

CRISPR增强型CAR T细胞免疫疗法的系统发现

Nature
IF48.5
2025-09-240
OAAI
Paul Datlinger; Eugenia V. Pankevich; Cosmas D. Arnold; Nicole Pranckevicius; Jenny Lin; Daria Romanovskaia; Moritz Schaefer; Francesco Piras; Anne-Christine Orts; Amelie Nemc; Paulina N. Biesaga; Michelle Chan; Teresa Neuwirth; Artem V. Artemov; Wentao Li; Sabrina Ladstätter; Thomas Krausgruber; Christoph Bock
Single-cell multi-omics characterize colorectal tumors, adjacent healthy tissue and matched (tumor) organoids identifying CRC-unique features

单细胞多组学分析表征了结直肠肿瘤、相邻健康组织及匹配的（肿瘤）类器官，并识别了CRC（结直肠癌）特有的特征。

International Journal of Cancer
IF4.7
2025-08-230
OAAI
Zhijun Yu; Merel Derksen; Brigit M. te Pas; Sabrina Ladstätter; Rene Overmeer; Peter Brazda; Marc van de Wetering; Farzin Pourfarzad; Robert G. J. Vries; Wout Megchelenbrink; Christoph Bock; Lucia Altucci; Hendrik G. Stunnenberg
Integrated time-series analysis and high-content CRISPR screening delineate the dynamics of macrophage immune regulation

整合时间序列分析和高通量CRISPR筛选以阐明巨噬细胞免疫调控的动态变化

Cell Systems
IF7.7
2025-08-080
OA
Peter Traxler; Stephan Reichl; Lukas Folkman; Lisa Shaw; Victoria Fife; Amelie Nemc; Djurdja Pasajlic; Anna Kusienicka; Daniele Barreca; Nikolaus Fortelny; André F. Rendeiro; Florian Halbritter; Wolfgang Weninger; Thomas Decker; Matthias Farlik; Christoph Bock
Unveiling genetic signatures of immune response in immune-related diseases through single-cell eQTL analysis across diverse conditions

通过不同条件下的单细胞eQTL分析揭示免疫相关疾病中免疫反应的遗传标志物

Nature Communications
IF15.7
2025-08-040
OAAI
Zhenhua Zhang; Wenchao Li; Qiuyao Zhan; Michelle Aillaud; Javier Botey-Bataller; Martijn Zoodsma; Rob ter Horst; Leo A. B. Joosten; Christoph Bock; Leon N. Schulte; Cheng-Jian Xu; Mihai G. Netea; Marc Jan Bonder; Yang Li
24-Nor-ursodeoxycholic acid improves intestinal inflammation by targeting TH17 pathogenicity and transdifferentiation

24-Nor-ursodeoxycholic acid通过靶向TH17致病性和转分化改善肠道炎症

GUT
IF25.8
2025-03-031
PRE
Zhu, Ci; Boucheron, Nicole; Al-Rubaye, Osamah; Chung, Brian K.; Thorbjornsen, Liv Wenche; Koecher, Thomas; Schuster, Michael; Claudel, Thierry; Halilbasic, Emina; Kunczer, Victoria; Muscate, Fanziska; Cavanagh, Lois L.; Waltenberger, Darina; Lercher, Alexander; Ohradanova-Repic, Anna; Schatzlmaier, Philipp; Stojakovic, Tatjana; Scharnagl, Hubert; Bergthaler, Andreas; Stockinger, Hannes; Huber, Samuel; Bock, Christoph; Kenner, Lukas; Karlsen, Tom H.
Cell-type-specific requirement for TYK2 in murine immune cells under steady state and challenged conditions
CELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
2025-03-020
OAAI
Karjalainen, Anzhelika; Witalisz-Siepracka, Agnieszka; Prchal-Murphy, Michaela; Martin, David; Sternberg, Felix; Krunic, Milica; Dolezal, Marlies; Fortelny, Nikolaus; Farlik, Matthias; Macho-Maschler, Sabine; Lassnig, Caroline; Meissl, Katrin; Amenitsch, Lena; Lederer, Therese; Pohl, Elena; Gotthardt, Dagmar; Bock, Christoph; Decker, Thomas; Strobl, Birgit; Mueller, Mathias
Nuclear receptor corepressor 1 controls regulatory T cell subset differentiation and effector function

核受体抑制因子1控制调节性T细胞亚群分化和效应子功能

ELIFE
IF0
2024-10-280
OA
Stolz, Valentina; de Freitas e Silva, Rafael; Rica, Ramona; Zhu, Ci; Preglej, Teresa; Hamminger, Patricia; Hainberger, Daniela; Alteneder, Marlis; Mueller, Lena; Waldherr, Monika; Waltenberger, Darina; Hladik, Anastasiya; Agerer, Benedikt; Schuster, Michael; Frey, Tobias; Krausgruber, Thomas; Knapp, Sylvia; Campbell, Clarissa; Schmetterer, Klaus; Trauner, Michael; Bergthaler, Andreas; Bock, Christoph; Boucheron, Nicole; Ellmeier, Wilfried
Targeting T cell plasticity in kidney and gut inflammation by pooled single-cell CRISPR screening
SCIENCE IMMUNOLOGY
IF16.3
2024-06-140
PRE
Enk, Leon U. B.; Hellmig, Malte; Riecken, Kristoffer; Kilian, Christoph; Datlinger, Paul; Jauch-Speer, Saskia L.; Neben, Tobias; Sultana, Zeba; Sivayoganathan, Varshi; Borchers, Alina; Paust, Hans-Joachim; Zhao, Yu; Asada, Nariaki; Liu, Shuya; Agalioti, Theodora; Pelczar, Penelope; Wiech, Thorsten; Bock, Christoph; Huber, Tobias B.; Huber, Samuel; Bonn, Stefan; Gagliani, Nicola; Fehse, Boris; Panzer, Ulf; Krebs, Christian F.
JAK-STAT signaling maintains homeostasis in T cells and macrophages
NATURE IMMUNOLOGY
IF27.6
2024-04-246
OAAI
Fortelny, Nikolaus; Farlik, Matthias; Fife, Victoria; Gorki, Anna-Dorothea; Lassnig, Caroline; Maurer, Barbara; Meissl, Katrin; Dolezal, Marlies; Boccuni, Laura; Geetha, Aarathy Ravi Sundar Jose; Akagha, Mojoyinola Joanna; Karjalainen, Anzhelika; Shoebridge, Stephen; Farhat, Asma; Mann, Ulrike; Jain, Rohit; Tikoo, Shweta; Zila, Nina; Esser-Skala, Wolfgang; Krausgruber, Thomas; Sitnik, Katarzyna; Penz, Thomas; Hladik, Anastasiya; Suske, Tobias; Zahalka, Sophie; Senekowitsch, Martin; Barreca, Daniele; Halbritter, Florian; Macho-Maschler, Sabine; Weninger, Wolfgang; Neubauer, Heidi A.; Moriggl, Richard; Knapp, Sylvia; Sexl, Veronika; Strobl, Birgit; Decker, Thomas; Mueller, Mathias; Bock, Christoph

研究方向

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T
Thomas Krausgruber
H 指数:35论文数:106被引数:8,626
M
Michael Schuster
H 指数:46论文数:164被引数:1.6万
M
Matthias Farlik
H 指数:41论文数:175被引数:7,838
A
Alexander Meissner
H 指数:98论文数:423被引数:6.8万
A
André F. Rendeiro
H 指数:32论文数:115被引数:8,108
T
Thomas Penz
H 指数:27论文数:86被引数:3,619
S
Stefan Kubicek
H 指数:54论文数:414被引数:1.4万
T
Thomas Lengauer
H 指数:84论文数:706被引数:4.2万
P
Paul Datlinger
H 指数:17论文数:34被引数:4,204
N
Nikolaus Fortelny
H 指数:28论文数:113被引数:3,384