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收藏Consequences of Amyloid-β Deficiency for the LiverΒ 淀粉样蛋白缺乏对肝脏的影响
Buniatian, Gayane Hrachia; Schwinghammer, Ute; Tremmel, Roman; Cynis, Holger; Weiss, Thomas S.; Weiskirchen, Ralf; Lauschke, Volker M.; Youhanna, Sonia; Ramos, Isbaal; Valcarcel, Maria; Seferyan, Torgom; Rahfeld, Jens-Ulrich; Rieckmann, Vera; Klein, Kathrin; Buadze, Marine; Weber, Victoria; Kolak, Valentina; Gebhardt, Rolf; Friedman, Scott L.; Mueller, Ulrike C.; Schwab, Matthias; Danielyan, Lusine
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收藏Hepatic Hedgehog Signaling Participates in the Crosstalk between Liver and Adipose Tissue in Mice by Regulating FGF21
Ott, Fritzi; Koerner, Christiane; Werner, Kim; Gericke, Martin; Liebscher, Ines; Lobsien, Donald; Radrezza, Silvia; Shevchenko, Andrej; Hofmann, Ute; Kratzsch, Juergen; Gebhardt, Rolf; Berg, Thomas; Matz-Soja, Madlen
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收藏Cyclopamine and Rapamycin Synergistically Inhibit mTOR Signalling in Mouse Hepatocytes, Revealing an Interaction of Hedgehog and mTor Signalling in the Liver
Spormann, Luise; Rennert, Christiane; Kolbe, Erik; Ott, Fritzi; Lossius, Carolin; Lehmann, Robert; Gebhardt, Rolf; Berg, Thomas; Matz-Soja, Madlen
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收藏Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver
Buniatian, Gayane Hrachia; Weiskirchen, Ralf; Weiss, Thomas S.; Schwinghammer, Ute; Fritz, Martin; Seferyan, Torgom; Proksch, Barbara; Glaser, Michael; Lourhmati, Ali; Buadze, Marine; Borkham-Kamphorst, Erawan; Gaunitz, Frank; Gleiter, Christoph H.; Lang, Thomas; Schaeffeler, Elke; Tremmel, Roman; Cynis, Holger; Frey, William H., II; Gebhardt, Rolf; Friedman, Scott L.; Mikulits, Wolfgang; Schwab, Matthias; Danielyan, Lusine
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收藏HepaChip-MP - a twenty-four chamber microplate for a continuously perfused liver coculture model
Busche, Marius; Tomilova, Olena; Schuette, Julia; Werner, Simon; Beer, Meike; Groll, Nicola; Hagmeyer, Britta; Pawlak, Michael; Jones, Peter D.; Schmees, Christian; Becker, Holger; Schnabel, Juliane; Gall, Karsten; Hemmler, Roland; Matz-Soja, Madlen; Damm, Georg; Beuck, Simon; Klaassen, Tobias; Moer, Jana; Ullrich, Anett; Runge, Dieter; Schenke-Layland, Katja; Gebhardt, Rolf; Stelzle, Martin
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收藏Influence of Liver Fibrosis on Lobular Zonation肝纤维化对小叶分区的影响
Ghallab, Ahmed; Myllys, Maiju; Holland, Christian H.; Zaza, Ayham; Murad, Walaa; Hassan, Reham; Ahmed, Yasser A.; Abbas, Tahany; Abdelrahim, Eman A.; Schneider, Kai Markus; Matz-Soja, Madlen; Reinders, Joerg; Gebhardt, Rolf; Berres, Marie-Luise; Hatting, Maximilian; Drasdo, Dirk; Saez-Rodriguez, Julio; Trautwein, Christian; Hengstler, Jan G.
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收藏Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and HumanWnt和Hh信号的相互作用正在协调小鼠和人类成年肝脏的代谢
Kolbe, Erik; Aleithe, Susanne; Rennert, Christiane; Spormann, Luise; Ott, Fritzi; Meierhofer, David; Gajowski, Robert; Stoepel, Claus; Hoehme, Stefan; Kuecken, Michael; Brusch, Lutz; Seifert, Michael; von Schoenfels, Witigo; Schafmayer, Clemens; Brosch, Mario; Hofmann, Ute; Damm, Georg; Seehofer, Daniel; Hampe, Jochen; Gebhardt, Rolf; Matz-Soja, Madlen
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收藏Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis
Marbach-Breitrueck, Eugenia; Matz-Soja, Madlen; Abraham, Ute; Schmidt-Heck, Wolfgang; Sales, Susanne; Rennert, Christiane; Kern, Matthias; Aleithe, Susanne; Spormann, Luise; Thiel, Carlo; Gerlini, Raffaele; Arnold, Katrin; Kloting, Nora; Guthke, Reinhard; Rozman, Damjana; Teperino, Raffaele; Shevchenko, Andrej; Kramer, Achim; Gebhardt, Rolf
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收藏The Wnt/β-catenin pathway determines the predisposition and efficiency of liver-to-pancreas reprogramming
Cohen, Helit; Barash, Hila; Meivar-Levy, Irit; Molakandov, Kfir; Ben-Shimon, Marina; Gurevich, Michael; Zoabi, Fatima; Har-Zahav, Adi; Gebhardt, Rolf; Gaunitz, Frank; Gurevich, Michael; Mor, Eytan; Ravassard, Philippe; Greenberger, Shoshana; Ferber, Sarah
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收藏Conditional loss of hepatocellular Hedgehog signaling in female mice leads to the persistence of hepatic steroidogenesis, androgenization and infertility
Rennert, Christiane; Eplinius, Franziska; Hofmann, Ute; Johaenning, Janina; Rolfs, Franziska; Schmidt-Heck, Wolfgang; Guthke, Reinhardt; Gebhardt, Rolf; Ricken, Albert M.; Matz-Soja, Madlen
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收藏Hedgehog signalling in myeloid cells impacts on body weight, adipose tissue inflammation and glucose metabolism
Braune, Julia; Weyer, Ulrike; Matz-Soja, Madlen; Hobusch, Constance; Kern, Matthias; Kunath, Anne; Kloeting, Nora; Kralisch, Susann; Blueher, Matthias; Gebhardt, Rolf; Zavros, Yana; Bechmann, Ingo; Gericke, Martin
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收藏Disrupting Hepatocyte Cyp51 from Cholesterol Synthesis Leads to Progressive Liver Injury in the Developing Mouse and Decreases RORC Signalling破坏胆固醇合成的肝细胞Cyp51导致发育中的小鼠进行性肝损伤并降低RORC信号传导
Urlep, Ziga; Lorbek, Gregor; Perse, Martina; Jeruc, Jera; Juvan, Peter; Matz-Soja, Madlen; Gebhardt, Rolf; Bjorkhem, Ingemar; Hall, Jason A.; Bonneau, Richard; Littman, Dan R.; Rozman, Damjana
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收藏Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue
Godoy, Patricio; Widera, Agata; Schmidt-Heck, Wolfgang; Campos, Gisela; Meyer, Christoph; Cadenas, Cristina; Reif, Raymond; Stoeber, Regina; Hammad, Seddik; Puetter, Larissa; Gianmoena, Kathrin; Marchan, Rosemarie; Ghallab, Ahmed; Edlund, Karolina; Nuessler, Andreas; Thasler, Wolfgang E.; Damm, Georg; Seehofer, Daniel; Weiss, Thomas S.; Dirsch, Olaf; Dahmen, Uta; Gebhardt, Rolf; Chaudhari, Umesh; Meganathan, Kesavan; Sachinidis, Agapios; Kelm, Jens; Hofmann, Ute; Zahedi, Rene P.; Guthke, Reinhard; Bluethgen, Nils; Dooley, Steven; Hengstler, Jan G.
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收藏Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis
Matz-Soja, Madlen; Rennert, Christiane; Schoenefeld, Kristin; Aleithe, Susanne; Boettger, Jan; Schmidt-Heck, Wolfgang; Weiss, Thomas S.; Hovhannisyan, Amalya; Zellmer, Sebastian; Kloeting, Nora; Schulz, Angela; Kratzsch, Juergen; Guthke, Reinhardt; Gebhardt, Rolf
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收藏Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases
Ghallab, Ahmed; Celliere, Geraldine; Henkel, Sebastian G.; Driesch, Dominik; Hoehme, Stefan; Hofmann, Ute; Zellmer, Sebastian; Godoy, Patricio; Sachinidis, Agapios; Blaszkewicz, Meinolf; Reif, Raymond; Marchan, Rosemarie; Kuepfer, Lars; Haeussinger, Dieter; Drasdo, Dirk; Gebhardt, Rolf; Hengstler, Jan G.
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