Soner Altiok - Publications, H-index & Citations

Soner Altiok

State University System of Florida

30H指数

187论文数

4.6K被引数

收录论文 46

发表时间

MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion MUC1是STAT3的下游靶标，并调控肺癌细胞生存和侵袭

International Journal of Oncology

IF4.9

2026-02-01

PREAI

Gao, Jingchun; McConnell, Matthew J.; Yu, Bin; Li, Jiannong; Balko, Justin M.; Black, Esther P.; Johnson, Joseph O.; Lloyd, Mark C.; Altiok, Soner; Haura, Eric B.

A novel ex vivo platform, 3D-EXpress, to rapidly assess the efficacy of KRAS targeting drugs alone and in combination with nivolumab using a biorepository of fresh patient tumoroids with intact tumor microenvironment

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Ehrhart, Jared; Ruedlinger, Brittney; Rivera, Angie; Ezeoke, Romanus; Camacho, Sharon; Currlin, Seth; Altiok, Soner

3D-EXplore platform of fresh patient tumoroids with intact TME allows assessment of the efficacy of drugs targeting the tumor stroma on ex vivo tumor immunotherapy

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Currlin, Seth; Ruedlinger, Brittney; Camacho, Sharon; Rivera, Angie; D'Andrea, Jasmin; Ehrhart, Jared; Altiok, Soner

3D-EXpress ex vivo platform using a biorepository of characterized fresh patient tumoroids allows development of rational combinations with drugs targeting DNA damage response and immune checkpoint blockade

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Ehrhart, Jared; Currlin, Seth; Camacho, Sharon; Hoffman, Samantha; Rivera, Angie; Altiok, Soner

3D-EXpress platform utilizing tumoroids from patients with MSS and MSI-H tumors allows rapid assessment of anti-tumor activity of immune checkpoint inhibitors and development of clinically relevant biomarkers of treatment response

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Ruedlinger, Brittney; Currlin, Seth; Camacho, Sharon; Humphrey, Alliyah; Ehrhart, Jared; Altiok, Soner

INTEGRATIVE ANALYSIS OF SINGLE CELL MULTIOMICS DATA USING DEEP LEARNING TO IDENTIFY IMMUNE RELATED BIOMARKERS IN A PATIENT DERIVED 3D EX VIVO TUMOROID PLATFORM

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2022-12-08

OAAI

Carl, Sarah; Flores-Candia, Juana; Staub, Jeremy; D'Andrea, Jasmin; Ruedlinger, Brittney; Shapland, Kate; Ehrhart, Jared; Altiok, Soner

CHARACTERIZATION OF THE SPATIAL AND TEMPORAL DISTRIBUTION OF TUMOR RESIDENT IMMUNE CELL POPULATIONS IN A 3DEXPLORE HUMAN TUMOROID MODEL AND ASSESSMENT OF RESPONSE TO IMMUNOTHERAPEUTICS EX VIVO

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2022-11-07

OAAI

Currlin, Seth; Camacho, Sharon; Rivera, Angie; Ehrhart, Jared; Altiok, Soner

AN EX VIVO 3D TUMOROID MODEL OF FRESH PATIENT TISSUE (3D-EXPLORE) TO ASSESS THE PHAGOCYTIC ACTIVITY OF TUMOR RESIDENT INNATE IMMUNE CELLS

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2021-11-10

OAAI

Guzman, Kelly; McIntosh, Olivia; Bunch, Brittany; Yarinsky, Jacob; Ehrhart, Jared; Altiok, Soner

SINGLE-CELL PROTEOGENOMICS (CITE-SEQ) ANALYSIS OF CGAS-STING PATHWAY ACTIVATION ALONE AND IN COMBINATION WITH NIVOLUMAB USING A PATIENT-DERIVED 3D EX VIVO TUMOROID PLATFORM

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2021-11-10

OAAI

Bunch, Brittany; Joerger, Autumn; Mtchedlidze, Nino; Hoff, Olivia; Guzman, Kelly; Ehrhart, Jared; Altiok, Soner

MONITORING THE IMPACT OF MDSC TARGETING DRUGS IN COMBINATION WITH NIVOLUMAB ON ACTIVATION AND PROLIFERATION OF TUMOR RESIDENT EFFECTOR IMMUNE CELLS IN PATIENT-DERIVED 3D-EXPLORE PLATFORM

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2021-11-10

OAAI

Ehrhart, Jared; Bunch, Brittany; Sussman, Kelly; Guzman, Kelly; Altiok, Soner

EVALUATING THE EFFECTIVENESS OF TARGETED ADC THERAPY IN A PATIENT-DERIVED EX VIVO TUMOROID MODEL, 3D-EX, FOR QUANTITATIVE TUMOR CELL KILLING

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2020-12-10

PREAI

Kreahling, Jenny; Ehrhart, Jared; Pabon, Mibel; Iwanowycz, Stephen; Pastoor, Tina; Altiok, Soner

DETERMINING THE EFFICACY OF ADCC BY THE 3D-EX EX VIVO PLATFORM UTILIZING TUMOROIDS OF FRESH PATIENT TUMOR SAMPLES WITH INTACT TUMOR MICROENVIRONMENT

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2020-12-10

PREAI

Kreahling, Jenny; Ehrhart, Jared; Iwanowycz, Stephen; Pabon, Mibel; Pastoor, Tina; Altiok, Soner

AN EX VIVO TUMOROID MODEL OF FRESH PATIENT TUMORS (3D-ACT) TO ASSESS EFFICACY OF CELLULAR THERAPY IN IMMUNO-ONCOLOGY

JOURNAL FOR IMMUNOTHERAPY OF CANCER

IF10.6

2020-11-09

PREAI

Iwanowycz, Stephen; Ehrhart, Jared; Pabon, Mibel; Pastoor, Tina; Kreahling, Jenny; Altiok, Soner

Optimization of checkpoint inhibitor-TKI combinations in renal cell carcinoma using an ex vivo 3D tumor organoid model of fresh patient tissue with intact TME

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Ehrhart, Jared C.; Pabon, Mibel M.; Agrawal, Vijayendra; Pastoor, Tina; Kreahling, Jenny M.; Altiok, Soner

Employing ex vivo 3D-Screen technology for the development of rational combinations of immuno-oncology drugs in tumor organoids of fresh patient tissue

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Agrawal, Vijayendra; Pabon, Mibel M.; Ehrhart, Jared C.; Pastoor, Tina; Kreahling, Jenny M.; Altiok, Soner

A novel ex vivo 3D tumor organoid model of fresh patient tumors (3D-ACT) to assess efficacy of cellular therapy in immuno-oncology

MOLECULAR CANCER THERAPEUTICS

IF5.5

2019-12-01

PREAI

Agrawal, Vijayendra; Pabon, Mibel; Page, Melba Marie; Kreahling, Jenny; Altiok, Soner

Impact of CDK4/6 inhibition on tumor immune microenvironment and immunomodulatory effects PD-L1 blockade in a physiologically relevant 3D-tumoroid model of fresh patient tumor tissue ex vivo

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Page, Melba Marie; Varela, Melanie Mediavilla; Agrawal, Vijayendra; Kreahling, Jenny; Altiok, Soner

The importance of intact tumor immune microenvironment in unpropagated 3D fresh patient tumoroids in immuno-oncology drug testing for immunogenic tumor cell death and T-cell activation

CANCER RESEARCH

IF16.6

2019-07-01

OAAI

Agrawal, Vijayendra; Mediavilla-Varela, Melanie; Page, Melba Marie; Kreahling, Jenny; Altiok, Soner

A high-content imaging platform for quantitative assessment of immunogenic tumor cell killing and T-cell proliferation in 3D tumoroids of fresh patient tumor samples

CANCER RESEARCH

IF16.6

2019-07-01

OAAI

Mediavilla-Varela, Melanie; Agrawal, Vijayendra; Page, Melba Marie; Kreahling, Jenny; Altiok, Soner

Identification of Synergistic, Clinically Achievable, Combination Therapies for Osteosarcoma

SCIENTIFIC REPORTS

IF3.9

2015-11-25

OAAI

Yu, Diana; Kahen, Elliot; Cubitt, Christopher L.; McGuire, Jeremy; Kreahling, Jenny; Lee, Jae; Altiok, Soner; Lynch, Conor C.; Sullivan, Daniel M.; Reed, Damon R.

研究方向