未登录 Therapeutic Potential of TLR8 Agonist GS-9688 (Selgantolimod) in Chronic Hepatitis B: Remodeling of Antiviral and Regulatory Mediators TLR8激动剂GS-9688 (Selgantolimod) 在慢性乙型肝炎中的治疗潜力: 抗病毒和调节介质的重塑 Amin, Oliver E.; Colbeck, Emily J.; Daffis, Stephane; Khan, Shahzada; Ramakrishnan, Dhivya; Pattabiraman, Divya; Chu, Ruth; Steuer, Holly Micolochick; Lehar, Sophie; Peiser, Leanne; Palazzo, Adam; Frey, Christian; Davies, Jessica; Javanbakht, Hassan; Rosenberg, William M. C.; Fletcher, Simon P.; Maini, Mala K.; Pallett, Laura J. 分享 收藏
Efficacy of an Inhibitor of Hepatitis B Virus Expression in Combination With Entecavir and Interferon-α in Woodchucks Chronically Infected With Woodchuck Hepatitis Virus Menne, Stephan; Wildum, Steffen; Steiner, Guido; Suresh, Manasa; Korolowicz, Kyle; Balarezo, Maria; Yon, Changsuek; Murreddu, Marta; Hong, Xupeng; Kallakury, Bhaskar, V; Tucker, Robin; Yang, Song; Young, John A. T.; Javanbakht, Hassan 分享 收藏
PAPD5/7 Are Host Factors That Are Required for Hepatitis B Virus RNA Stabilization PAPD5/7是乙型肝炎病毒RNA稳定所需的宿主因素 Mueller, Henrik; Lopez, Anais; Tropberger, Philipp; Wildum, Steffen; Schmaler, Josephine; Pedersen, Lykke; Han, Xingchun; Wang, Yongguang; Ottosen, Soren; Yang, Song; Young, John A. T.; Javanbakht, Hassan 分享 收藏
Discovery of RG7834: The First-in-Class Selective and Orally Available Small Molecule Hepatitis B Virus Expression Inhibitor with Novel Mechanism of Action Han, Xingchun; Zhou, Chengang; Jiang, Min; Wang, Yongguang; Wang, Jianhua; Cheng, Zhanling; Wang, Min; Liu, Yongqiang; Liang, Chungen; Wang, Jianping; Wang, Zhanguo; Weikert, Robert; Lv, Wenzhe; Xie, Jianxun; Yu, Xin; Zhou, Xue; Luangsay, Souphalone; Shen, Hong C.; Mayweg, Alexander V.; Javanbakht, Hassan; Yang, Song 分享 收藏
Liver-Targeted Anti-HBV Single-Stranded Oligonucleotides with Locked Nucleic Acid Potently Reduce HBV Gene Expression In Vivo Javanbakht, Hassan; Mueller, Henrik; Walther, Johanna; Zhou, Xue; Lopez, Anais; Pattupara, Thushara; Blaising, Julie; Pedersen, Lykke; Albaek, Nanna; Jackerott, Malene; Shi, Tianlai; Ploix, Corinne; Driessen, Wouter; Persson, Robert; Ravn, Jacob; Young, John A. T.; Ottosen, Soren 分享 收藏
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A novel orally available small molecule that inhibits hepatitis B virus expression 一种抑制乙型肝炎病毒表达的新型口服小分子 Mueller, Henrik; Wildum, Steffen; Luangsay, Souphalone; Walther, Johanna; Lopez, Anais; Tropberger, Philipp; Ottaviani, Giorgio; Lu, Wenzhe; Parrott, Neil John; Zhang, Jitao David; Schmucki, Roland; Racek, Tomas; Hoflack, Jean-Christophe; Kueng, Erich; Point, Floriane; Zhou, Xue; Steiner, Guido; Luetgehetmann, Marc; Rapp, Gianna; Volz, Tassilo; Dandri, Maura; Yang, Song; Young, John A. T.; Javanbakht, Hassan 分享 收藏
Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling Kratochwil, Nicole A.; Meille, Christophe; Fowler, Stephen; Klammers, Florian; Ekiciler, Aynur; Molitor, Birgit; Simon, Sandrine; Walter, Isabelle; McGinnis, Claudia; Walther, Johanna; Leonard, Brian; Triyatni, Miriam; Javanbakht, Hassan; Funk, Christoph; Schuler, Franz; Lave, Thierry; Parrott, Neil J. 分享 收藏
Antiviral efficacy of a novel hepatitis B virus expression inhibitor in combination with entecavir and wIFN-alpha in woodchucks model of chronic hepatitis B Wildum, S.; Steiner, G.; Luangsay, S.; Suresh, M.; Korolowicz, K.; Balarezo, M.; Yon, C.; Murreddu, M.; Hong, X.; Kallakury, B.; Tucker, R.; Mueller, H.; Menne, S.; Young, J.; Javanbakht, H. 分享 收藏
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Early inhibition of hepatocyte innate responses by hepatitis B virus Luangsay, Souphalone; Gruffaz, Marion; Isorce, Nathalie; Testoni, Barbara; Michelet, Maud; Faure-Dupuy, Suzanne; Maadadi, Sarah; Ait-Goughoulte, Malika; Parent, Romain; Rivoire, Michel; Javanbakht, Hassan; Lucifora, Julie; Durantel, David; Zoulim, Fabien 分享 收藏
Expression and functionality of Toll- and RIG-like receptors in HepaRG cells Luangsay, Souphalone; Ait-Goughoulte, Malika; Michelet, Maud; Floriot, Oceane; Bonnin, Marc; Gruffaz, Marion; Rivoire, Michel; Fletcher, Simon; Javanbakht, Hassan; Lucifora, Julie; Zoulim, Fabien; Durantel, David 分享 收藏
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Intracellular Effects of the Hepatitis C Virus Nucleoside Polymerase Inhibitor RO5855 ( Mericitabine Parent) and Ribavirin in Combination Ma, H.; Le Pogam, S.; Fletcher, S.; Hinojosa-Kirschenbaum, F.; Javanbakht, H.; Yan, J. -M.; Jiang, W. -R.; Inocencio, N.; Klumpp, K.; Najera, I. 分享 收藏
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HEPATITIS B CORE (HBC) PROTEIN IS A KEY AND VERY EARLY NEGATIVE REGULATOR OF THE INTERFERON RESPONSE Gruffaz, M.; Testoni, B.; Luangsay, S.; Ait-Goughoulte, M.; Petit, M-A; Ma, H.; Klumpp, K.; Javanbakht, H.; Durantel, D.; Zoulim, F. 分享 收藏
A Randomized, Double-Blind Placebo Controlled Trial of Balapiravir, a Polymerase Inhibitor, in Adult Dengue Patients Nguyet Minh Nguyen; Chau Nguyen Bich Tran; Lam Khanh Phung; Kien Thi Hue Duong; Huy Le Anh Huynh; Farrar, Jeremy; Quyen Than Ha Nguyen; Hien Tinh Tran; Chau Van Vinh Nguyen; Merson, Laura; Long Truong Hoang; Hibberd, Martin L.; Aw, Pauline P. K.; Wilm, Andreas; Nagarajan, Niranjan; Dung Thi Nguyen; Mai Phuong Pham; Truong Thanh Nguyen; Javanbakht, Hassan; Klumpp, Klaus; Hammond, Janet; Petric, Rosemary; Wolbers, Marcel; Chinh Tran Nguyen; Simmons, Cameron P. 分享 收藏
Diphenyl Ether Non-Nucleoside Reverse Transcriptase Inhibitors with Excellent Potency Against Resistant Mutant Viruses and Promising Pharmacokinetic Properties Sweeney, Zachary K.; Kennedy-Smith, Joshua J.; Wu, Jeffrey; Arora, Nidhi; Billedeau, J. Roland; Davidson, James R.; Fretland, Jennifer; Hang, Julie Q.; Heilek, Gabrielle M.; Harris, Seth F.; Hirschfeld, Donald; Inbar, Petra; Javanbakht, Hassan; Jernelius, Jesper A.; Jin, Qingwu; Li, Yu; Liang, Weiling; Roetz, Ralf; Sarma, Keshab; Smith, Mark; Stefanidis, Dimitrio; Su, Guoping; Suh, Judy M.; Villasenor, Armando G.; Welch, Michael; Zhang, Fang-Jie; Klumpp, Klaus 分享 收藏
Design of Annulated Pyrazoles as Inhibitors of HIV-1 Reverse Transcriptase Sweeney, Zachary K.; Harris, Seth F.; Arora, Nidhi; Javanbakht, Hassan; Li, Yu; Fretland, Jennifer; Davidson, James P.; Billedeau, J. Roland; Gleason, Shelle K.; Hirschfeld, Donald; Kennedy-Smith, Joshua J.; Mirzadegan, Taraneh; Roetz, Ralf; Smith, Mark; Sperry, Sarah; Suh, Judy M.; Wu, Jeffrey; Tsing, Stan; Villasenor, Armando G.; Paul, Amber; So, Guoping; Heilek, Gabrielle; Hang, Julie Q.; Zhou, Amy S.; Jernelius, Jesper A.; Zhang, Fang-Jie; Klumpp, Klaus 分享 收藏
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