未登录 Acute myeloid leukemia stratifies as 2 clinically relevantsphingolipidomic subtypes 急性髓性白血病分为2种临床相关的鞘脂组亚型 Paudel, B. Bishal; Tan, Su-Fern; Fox, Todd E.; Ung, Johnson; Golla, Upendarrao; Shaw, Jeremy J. P.; Dunton, Wendy; Lee, Irene; Fares, Wisam A.; Patel, Satyam; Sharma, Arati; Viny, Aaron D.; Barth, Brian M.; Tallman, Martin S.; Cabot, Myles; Garrett-Bakelman, Francine E.; Levine, Ross L.; Kester, Mark; Feith, David J.; Claxton, David; Janes, Kevin A.; Loughran, Thomas P. 分享 收藏
Pronecroptotic Therapy Using Ceramide Nanoliposomes Is Effective for Triple-Negative Breast Cancer Cells Ohya, Yuki; Ogiso, Yuri; Matsuda, Masaya; Sakae, Harumi; Nishida, Kentaro; Miki, Yasuhiro; Fox, Todd E.; Kester, Mark; Sakamoto, Wataru; Nabe, Takeshi; Kitatani, Kazuyuki 分享 收藏
PP2A modulation overcomes multidrug resistance in chronic lymphocytic leukemia via mPTP-dependent apoptosis Jayappa, Kallesh D.; Tran, Brian; Gordon, Vicki L.; Morris, Christopher; Saha, Shekhar; Farrington, Caroline C.; O'Connor, Caitlin M.; Zawacki, Kaitlin P.; Isaac, Krista M.; Kester, Mark; Bender, Timothy P.; Williams, Michael E.; Portell, Craig A.; Weber, Michael J.; Narla, Goutham 分享 收藏
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Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia Khokhlatchev, Andrei, V; Sharma, Arati; Deering, Tye G.; Shaw, Jeremy J. P.; Costa-Pinheiro, Pedro; Golla, Upendarrao; Annageldiyev, Charyguly; Cabot, Myles C.; Conaway, Mark R.; Tan, Su-Fern; Ung, Johnson; Feith, David J.; Loughran, Thomas P., Jr.; Claxton, David F.; Fox, Todd E.; Kester, Mark 分享 收藏
Harnessing the power of sphingolipids: Prospects for acute myeloid leukemia Ung, Johnson; Tan, Su-Fern; Fox, Todd E.; Shaw, Jeremy J. P.; Vass, Luke R.; Costa-Pinheiro, Pedro; Garrett-Bakelman, Francine E.; Keng, Michael K.; Sharma, Arati; Claxton, David F.; Levine, Ross L.; Tallman, Martin S.; Cabot, Myles C.; Kester, Mark; Feith, David J.; Loughran, Thomas P. 分享 收藏
Influence of ceramide on lipid domain stability studied with small-angle neutron scattering: The role of acyl chain length and unsaturation 用小角度中子散射研究神经酰胺对脂质结构域稳定性的影响: 酰基链长和不饱和度的作用 DiPasquale, Mitchell; Deering, Tye G.; Desai, Dhimant; Sharma, Arun K.; Amin, Shantu; Fox, Todd E.; Kester, Mark; Katsaras, John; Marquardt, Drew; Heberle, Frederick A. 分享 收藏
Nanoliposome C6-Ceramide in combination with anti-CTLA4 antibody improves anti-tumor immunity in hepatocellular cancer Qi, Xiaoqiang; Wu, Feng; Kim, Sung Hoon; Kaifi, Jussuf T.; Kimchi, Eric T.; Snyder, Helena; Illendula, Anuradha; Fox, Todd; Kester, Mark; Staveley-O'Carroll, Kevin F.; Li, Guangfu 分享 收藏
Alterations in sphingolipid composition and mitochondrial bioenergetics represent synergistic therapeutic vulnerabilities linked to multidrug resistance in leukemia Fisher-Wellman, Kelsey H.; Hagen, James T.; Kassai, Miki; Kao, Li-Pin; Nelson, Margaret A. M.; McLaughlin, Kelsey L.; Coalson, Hannah S.; Fox, Todd E.; Tan, Su-Fern; Feith, David J.; Kester, Mark; Loughran, Thomas P. Jr Jr; Claxton, David F.; Cabot, Myles C. 分享 收藏
Minicells from Highly Genome Reduced Escherichia coli: Cytoplasmic and Surface Expression of Recombinant Proteins and Incorporation in the Minicells Yu, Hanna; Khokhlatchev, Andrei, V; Chew, Claude; Illendula, Anuradha; Conaway, Mark; Dryden, Kelly; Maeda, Denicar Lina Nascimento Fabris; Rajasekaran, Vignesh; Kester, Mark; Zeichner, Steven L. 分享 收藏
Minicell-based fungal RNAi delivery for sustainable crop protection Islam, Md Tabibul; Davis, Zachery; Chen, Lisa; Englaender, Jacob; Zomorodi, Sepehr; Frank, Joseph; Bartlett, Kira; Somers, Elisabeth; Carballo, Sergio M.; Kester, Mark; Shakeel, Ameer; Pourtaheri, Payam; Sherif, Sherif M. 分享 收藏
Inhibition of Lysosomal Function Mitigates Protective Mitophagy and Augments Ceramide Nanoliposome-Induced Cell Death in Head and Neck Squamous Cell Carcinoma Shaw, Jeremy J. P.; Boyer, Timothy L.; Venner, Emily; Beck, Patrick J.; Slamowitz, Tristen; Caste, Tara; Hickman, Alexandra; Raymond, Michael H.; Costa-Pinheiro, Pedro; Jameson, Mark J.; Fox, Todd E.; Kester, Mark 分享 收藏
Glucosylceramide production maintains colon integrity in response toBacteroides fragilistoxin-induced colon epithelial cell signaling Patterson, Logan; Allen, Jawara; Posey, Isabella; Shaw, Jeremy Joseph Porter; Costa-Pinheiro, Pedro; Walker, Susan J.; Gademsey, Alexis; Wu, Xinqun; Wu, Shaoguang; Zachos, Nicholas C.; Fox, Todd E.; Sears, Cynthia L.; Kester, Mark 分享 收藏
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Exogenous Liposomal Ceramide-C6 Ameliorates Lipidomic Profile, Energy Homeostasis, and Anti-Oxidant Systems in NASH Zanieri, Francesca; Levi, Ana; Montefusco, David; Longato, Lisa; De Chiara, Francesco; Frenguelli, Luca; Omenetti, Sara; Andreola, Fausto; Tu Vinh Luong; Massey, Veronica; Caballeria, Juan; Fondevila, Constantino; Shanmugavelandy, Sriram S.; Fox, Todd; Mazza, Giuseppe; Argemi, Josepmaria; Bataller, Ramon; Cowart, Lauren Ashley; Kester, Mark; Pinzani, Massimo; Rombouts, Krista 分享 收藏
Ceramide Analogue SACLAC Modulates Sphingolipid Levels and MCL-1 Splicing to Induce Apoptosis in Acute Myeloid Leukemia 神经酰胺类似物SACLAC调节鞘脂水平和MCL-1剪接以诱导急性髓系白血病的细胞凋亡 Pearson, Jennifer M.; Tan, Su-Fern; Sharma, Arati; Annageldiyev, Charyguly; Fox, Todd E.; Abad, Jose Luis; Fabrias, Gemma; Desai, Dhimant; Amin, Shantu; Wang, Hong-Gang; Cabot, Myles C.; Claxton, David F.; Kester, Mark; Feith, David J.; Loughran, Thomas P. 分享 收藏
Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia Barth, Brian M.; Wang, Weiyuan; Toran, Paul T.; Fox, Todd E.; Annageldiyev, Charyguly; Ondrasik, Regina M.; Keasey, Nicole R.; Brown, Timothy J.; Devine, Viola G.; Sullivan, Emily C.; Cote, Andrea L.; Papakotsi, Vasiliki; Tan, Su-Fern; Shanmugavelandy, Sriram S.; Deering, Tye G.; Needle, David B.; Stern, Stephan T.; Zhu, Junjia; Liao, Jason; Viny, Aaron D.; Feith, David J.; Levine, Ross L.; Wang, Hong-Gang; Loughran, Thomas P., Jr.; Sharma, Arati; Kester, Mark; Claxton, David F. 分享 收藏
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