未登录 Autoantibody repertoire characterization provides insight into the pathogenesis of monogenic and polygenic autoimmune diseases 自身抗体库表征可深入了解单基因和多基因自身免疫性疾病的发病机理 Clarke, Thomas; Du, Pan; Kumar, Satyendra; Okitsu, Shinji L.; Schuette, Mark; An, Qi; Zhang, Jinyang; Tzvetkov, Evgeni; Jensen, Mark A.; Niewold, Timothy B.; Ferre, Elise M. N.; Nardone, Julie; Lionakis, Michail S.; Vlach, Jaromir; DeMartino, Julie; Bender, Andrew T. 分享 收藏
分享 收藏
Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization Banga, Jaspreet; Srinivasan, Dinesh; Sun, Chia-Chi; Thompson, Cherrie D.; Milletti, Francesca; Huang, Kuo-Sen; Hamilton, Shannon; Song, Su; Hoffman, Ann F.; Qin, Yajuan Gu; Matta, Bharati; Lapan, Margaret; Guo, Qin; Lu, Gang; Li, Dan; Qian, Hong; Bolin, David R.; Liang, Lena; Wartchow, Charles; Qiu, Jin; Downing, Michelle; Narula, Satwant; Fotouhi, Nader; Demartino, Julie A.; Tan, Seng-Lai; Chen, Gang; Barnes, Betsy J. 分享 收藏
Pharmacological Characterization of a Novel Beta 3 Adrenergic Agonist, Vibegron: Evaluation of Antimuscarinic Receptor Selectivity for Combination Therapy for Overactive Bladder Di Salvo, J.; Nagabukuro, H.; Wickham, L. A.; Abbadie, C.; DeMartino, J. A.; Fitzmaurice, A.; Gichuru, L.; Kulick, A.; Donnelly, M. J.; Jochnowitz, N.; Hurley, A. L.; Pereira, A.; Sanfiz, A.; Veronin, G.; Villa, K.; Woods, J.; Zamlynny, B.; Zycband, E.; Salituro, G. M.; Frenkl, T.; Weber, A. E.; Edmondson, S. D.; Struthers, M. 分享 收藏
Discovery of N-[Bis(4-methoxyphenyl)methy1]-4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamide (MK-8617), an Orally Active Pan-Inhibitor of Hypoxia-Inducible Factor Prolyl Hydroxylase 1-3 (HIF PHD1-3) for the Treatment of Anemia Debenham, John S.; Madsen-Duggan, Christina; Clements, Matthew J.; Walsh, Thomas F.; Kuethe, Jeffrey T.; Reibarkh, Mikhail; Salowe, Scott P.; Sonatore, Lisa M.; Hajdu, Richard; Milligan, James A.; Visco, Denise M.; Zhou, Dan; Lingham, Russell B.; Stickens, Dominique; DeMartino, Julie A.; Tong, Xinchun; Wolff, Michael; Pang, Jianmei; Miller, Randy R.; Sherer, Edward C.; Hale, Jeffrey J. 分享 收藏
Btk inhibition suppresses agonist-induced human macrophage activation and inflammatory gene expression in RA synovial tissue explants Hartkamp, Linda M.; Fine, Jay S.; van Es, Inge E.; Tang, Man Wai; Smith, Michael; Woods, John; Narula, Satwant; DeMartino, Julie; Tak, Paul P.; Reedquist, Kris A. 分享 收藏
TL1A/TNFSF15 directly induces proinflammatory cytokines, including TNFα, from CD3+CD161+T cells to exacerbate gut inflammation Jin, S.; Chin, J.; Seeber, S.; Niewoehner, J.; Weiser, B.; Beaucamp, N.; Woods, J.; Murphy, C.; Fanning, A.; Shanahan, F.; Nally, K.; Kajekar, R.; Salas, A.; Planell, N.; Lozano, J.; Panes, J.; Parmar, H.; DeMartino, J.; Narula, S.; Thomas-Karyat, D. A. 分享 收藏
Characterization of a novel CRAC inhibitor that potently blocks human T cell activation and effector functions Chen, Gang; Panicker, Sandip; Lau, Kai-Yeung; Apparsundaram, Subramaniam; Patel, Vaishali A.; Chen, Shiow-Ling; Soto, Rothschild; Jung, Jimmy K. C.; Ravindran, Palanikumar; Okuhara, Dayne; Bohnert, Gary; Che, Qinglin; Rao, Patricia E.; Allard, John D.; Badi, Laura; Bitter, Hans-Marcus; Nunn, Philip A.; Narula, Satwant K.; DeMartino, Julie A. 分享 收藏
分享 收藏
分享 收藏
BET Bromodomain Proteins Mediate Downstream Signaling Events following Growth Factor Stimulation in Human Lung Fibroblasts and Are Involved in Bleomycin-Induced Pulmonary Fibrosiss Tang, Xiaoyan; Peng, Ruoqi; Ren, Yonglin; Apparsundaram, Subramanium; Deguzman, Jeremy; Bauer, Carla M.; Hoffman, Ann F.; Hamilton, Shannon; Liang, Zhenmin; Zeng, Hang; Fuentes, Maria E.; DeMartino, Julie A.; Kitson, Christopher; Stevenson, Christopher S.; Budd, David C. 分享 收藏
Evidence for cyclic diguanylate as a vaccine adjuvant with novel immunostimulatory activities Gray, Peter M.; Forrest, Gail; Wisniewski, Thomas; Porter, Gene; Freed, Daniel C.; DeMartino, Julie A.; Zaller, Dennis M.; Guo, Zhiqiang; Leone, Joseph; Fu, Tong-Ming; Vora, Kalpit A. 分享 收藏
RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents Xu, Daigen; Kim, Yong; Postelnek, Jennifer; Minh Diem Vu; Hu, Dong-Qing; Liao, Cheng; Bradshaw, Mike; Hsu, Jonathan; Zhang, Jun; Pashine, Achal; Srinivasan, Dinesh; Woods, John; Levin, Anita; O'Mahony, Alison; Owens, Timothy D.; Lou, Yan; Hill, Ronald J.; Narula, Satwant; DeMartino, Julie; Fine, Jay S. 分享 收藏
1,3,8-Triazaspiro[4.5]decane-2,4-diones as Efficacious Pan-Inhibitors of Hypoxia-Inducible Factor Prolyl Hydroxylase 1-3 (HIF PHD1-3) for the Treatment of Anemia Vachal, Petr; Miao, Shouwu; Pierce, Joan M.; Guiadeen, Deodial; Colandrea, Vincent J.; Wyvratt, Matthew J.; Salowe, Scott P.; Sonatore, Lisa M.; Milligan, James A.; Hajdu, Richard; Gollapudi, Anantha; Keohane, Carol A.; Lingham, Russell B.; Mandala, Suzanne M.; DeMartino, Julie A.; Tong, Xinchun; Wolff, Michael; Steinhuebel, Dietrich; Kieczykowski, Gerard R.; Fleitz, Fred J.; Chapman, Kevin; Athanasopoulos, John; Adam, Gregory; Akyuz, Can D.; Jena, Dhirendra K.; Lusen, Jeffrey W.; Meng, Juncai; Stein, Benjamin D.; Xia, Lei; Sherer, Edward C.; Hale, Jeffrey J. 分享 收藏
Optimization of erythropoietin production with controlled glycosylation-PEGylated erythropoietin produced in glycoengineered Pichia pastoris Nett, Juergen H.; Gomathinayagam, Sujatha; Hamilton, Stephen R.; Gong, Bing; Davidson, Robert C.; Du, Min; Hopkins, Daniel; Mitchell, Teresa; Mallem, Muralidhar R.; Nylen, Adam; Shaikh, Seemab S.; Sharkey, Nathan; Barnard, Gavin C.; Copeland, Victoria; Liu, Liming; Evers, Raymond; Li, Yan; Gray, Peter M.; Lingham, Russell B.; Visco, Denise; Forrest, Gail; DeMartino, Julie; Linden, Thomas; Potgieter, Thomas I.; Wildt, Stefan; Stadheim, Terrance A.; d'Anjou, Marc; Li, Huijuan; Sethuraman, Natarajan 分享 收藏
Discovery of a Potent and Orally Bioavailable CCR2 and CCR5 Dual Antagonist Pasternak, Alexander; Goble, Stephen D.; Struthers, Mary; Vicario, Pasquale P.; Ayala, Julia M.; Di Salvo, Jerry; Kilburn, Ruth; Wisniewski, Thomas; DeMartino, Julie A.; Mills, Sander G.; Yang, Lihu 分享 收藏
Unaltered graft survival and intragraft lymphocytes infiltration in the cardiac allograft of Cxcr3-/- mouse recipients Kwun, J.; Hazinedaroglu, S. M.; Schadde, E.; Kayaoglu, H. A.; Fechner, J.; Hu, H. Z.; Roenneburg, D.; Torrealba, J.; Shiao, L.; Hong, X.; Peng, R.; Szewczyk, J. W.; Sullivan, K. A.; DeMartino, J.; Knechtle, S. J. 分享 收藏
Fused bicyclic pyrrolizinones as new scaffolds for human NK1 antagonists Morriello, Gregori J.; DeVita, Robert J.; Mills, Sander G.; Young, Jonathan R.; Lin, Peter; Doss, George; Chicchi, Gary G.; DeMartino, Julie; Kurtz, Marc M.; Tsao, Kwei-Lan C.; Carlson, Emma; Townson, Karen; Wheeldon, Alan; Boyce, Susan; Collinson, Neil; Rupniak, Nadia; Moore, Stephen 分享 收藏
分享 收藏
CCR5 blockade modulates inflammation and alloimmunity in primates Schroeder, Carsten; Pierson, Richard N., III; Nguyen, Bao-Ngoc H.; Kawka, Douglas W.; Peterson, Laurence B.; Wu, Guosheng; Zhang, Tianshu; Springer, Martin S.; Siciliano, Sal J.; Iliff, Susan; Ayala, Julia M.; Lu, Min; Mudgett, John S.; Lyons, Kathy; Mills, Sander G.; Miller, Geraldine G.; Singer, Irwin.; Azimzadeh, Agnes M.; DeMartino, Julie A. 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
