未登录 GDF15 is a dynamic biomarker of the integrated stress response in the central nervous system GDF15是中枢神经系统综合应激反应的动态生物标志物 Asundi, Jyoti; Zhang, Chunlian; Donnelly-Roberts, Diana; Solorio, Jose Zavala; Challagundla, Malleswari; Connelly, Caitlin; Boch, Christina; Chen, Jun; Richter, Mario; Maneshi, Mohammad Mehdi; Swensen, Andrew M.; Lebon, Lauren; Schiffmann, Raphael; Sanyal, Subhabrata; Sidrauski, Carmela; Kolumam, Ganesh; Baruch, Amos 分享 收藏
Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design Dietrich, Justin D.; Longenecker, Kenton L.; Wilson, Noel S.; Goess, Christian; Panchal, Sanjay C.; Swann, Steven L.; Petros, Andrew M.; Hobson, Adrian D.; Ihle, David; Song, Danying; Richardson, Paul; Comess, Kenneth M.; Cox, Philip B.; Dombrowski, Amanda; Sarris, Kathy; Donnelly-Roberts, Diana L.; Duignan, David B.; Gomtsyan, Arthur; Jung, Paul; Krueger, A. Chris; Mathieu, Suzanne; McClure, Andrea; Stoll, Vincent S.; Wetter, Jill; Mankovich, John A.; Hajduk, Philip J.; Vasudevan, Anil; Stoffel, Robert H.; Sun, Chaohong 分享 收藏
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Small Molecule and Pooled CRISPR Screens Investigating IL17 Signaling Identify BRD2 as a Novel Contributor to Keratinocyte Inflammatory Responses Slivka, Peter F.; Hsieh, Chen-Lin; Lipovsky, Alex; Pratt, Steven D.; Locklear, John; Namovic, Marian T.; McDonald, Heath A.; Wetter, Joseph; Edelmayer, Rebecca; Hu, Min; Murphy, Erin; Domanus, Marc; Lu, Charles; Duggan, Ryan; King, Jacob; Scott, Victoria E.; Donnelly-Roberts, Diana; Slavin, Anthony; Gopalakrishnan, Sujatha; Chung, Namjin; Goedken, Eric R. 分享 收藏
eIF2B activator prevents neurological defects caused by a chronic integrated stress response Wong, Yao Liang; LeBon, Lauren; Basso, Ana M.; Kohlhaas, Kathy L.; Nikkel, Arthur L.; Robb, Holly M.; Donnelly-Roberts, Diana L.; Prakash, Janani; Swensen, Andrew M.; Rubinstein, Nimrod D.; Krishnan, Swathi; McAllister, Fiona E.; Haste, Nicole, V; O'Brien, Jonathon J.; Roy, Margaret; Ireland, Andrea; Frost, Jennifer M.; Shi, Lei; Riedmaier, Stephan; Martin, Kathleen; Dart, Michael J.; Sidrauski, Carmela 分享 收藏
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Longitudinal Changes in Measured Glomerular Filtration Rate, Renal Fibrosis and Biomarkers in a Rat Model of Type 2 Diabetic Nephropathy 2型糖尿病肾病大鼠模型中测得的肾小球滤过率、肾纤维化和生物标志物的纵向变化 Su, Zhi; Widomski, Deborah; Ma, Ji; Namovic, Marian; Nikkel, Arthur; Leys, Laura; Olson, Lauren; Salte, Katherine; Donnelly-Roberts, Diana; Esbenshade, Timothy; McGaraughty, Steve 分享 收藏
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Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists Minami, S. Sakura; Shen, Vivian; Le, David; Krabbe, Grietje; Asgarov, Rustam; Perez-Celajes, Liberty; Lee, Chih-Hung; Li, Jinhe; Donnelly-Roberts, Diana; Gan, Li 分享 收藏
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Synthesis and SAR of 4-aminocyclopentapyrrolidines as N-type Ca2+ channel blockers with analgesic activity Beebe, Xenia; Darczak, Daria; Henry, Rodger F.; Vortherms, Timothy; Janis, Richard; Namovic, Marian; Donnelly-Roberts, Diana; Kage, Karen L.; Surowy, Carol; Milicic, Ivan; Niforatos, Wende; Swensen, Andrew; Marsh, Kennan C.; Wetter, Jill M.; Franklin, Pamela; Baker, Scott; Zhong, Chengmin; Simler, Gricelda; Gomez, Erica; Boyce-Rustay, Janel M.; Zhu, Chang Z.; Stewart, Andrew O.; Jarvis, Michael F.; Scott, Victoria E. 分享 收藏
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A-582941, a pro-cognitive α7 nAChR agonist, differentially modulates mitochondrial membrane potential Namovic, Marian; Hu, Min; Abraham, Vivek; Towne, Danli; Lee, Chih-Hung; Gopalakrishnan, Murali; Esbenshade, Tim; Donnelly-Roberts, Diana 分享 收藏
Profile of A-716096, a novel thiazolylidine positive allosteric modulator of the α7 nicotinic acetylcholine receptor Donnelly-Roberts, D.; Malysz, J.; Faghih, R.; Gronlien, H.; Haakerud, M.; Thorin-Hagne, K.; Ween, H.; Gopalakrishnan, S. M.; Hu, M.; Li, J.; Anderson, D. J.; Kohlhaas, K.; Namovic, M.; Radek, R.; Robb, H.; Briggs, C. A.; Bitner, R. S.; Bunnelle, W. H.; Gopalakrishnan, M. 分享 收藏
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Discovery and Biological Evaluation of Novel Cyanoguanidine P2X7 Antagonists with Analgesic Activity in a Rat Model of Neuropathic Pain Perez-Medrano, Arturo; Donnelly-Roberts, Diana L.; Honore, Prisca; Hsieh, Gin C.; Namovic, Marian T.; Peddi, Sridhar; Shuai, Qi; Wang, Ying; Faltynek, Connie R.; Jarvis, Michael F.; Carroll, William A. 分享 收藏
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