Gerald M. Cohen - Publications, H-index & Citations

Gerald M. Cohen

university of leicester

81H指数

397论文数

3.4W被引数

收录论文 92

发表时间

Novel roles of RTN4 and CLIMP-63 in regulating mitochondrial structure, bioenergetics and apoptosis

CELL DEATH & DISEASE

IF9.6

2022-05-04

OAAI

Carter, Rachel J.; Milani, Mateus; Beckett, Alison J.; Liu, Shiyu; Prior, Ian A.; Cohen, Gerald M.; Varadarajan, Shankar

Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck

CELL DEATH & DISEASE

IF9.6

2019-12-04

OAAI

Carter, Rachel J.; Milani, Mateus; Butterworth, Michael; Alotibi, Ahoud; Harper, Nicholas; Yedida, Govindaraju; Greaves, Georgia; Al-Zebeeby, Aoula; Jorgensen, Andrea L.; Schache, Andrew G.; Risk, Janet M.; Shaw, Richard J.; Jones, Terry M.; Sacco, Joseph J.; Hurlstone, Adam; Cohen, Gerald M.; Varadarajan, Shankar

DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis

CELL DEATH DISCOVERY

IF7

2019-07-17

OAAI

Milani, Mateus; Beckett, Alison J.; Al-Zebeeby, Aoula; Luo, Xu; Prior, Ian A.; Cohen, Gerald M.; Varadarajan, Shankar

Apogossypol-mediated reorganisation of the endoplasmic reticulum antagonises mitochondrial fission and apoptosis

CELL DEATH & DISEASE

IF9.6

2019-07-08

OAAI

Yedida, Govindaraju; Milani, Mateus; Cohen, Gerald M.; Varadarajan, Shankar

Targeting intermediary metabolism enhances the efficacy of BH3 mimetic therapy in hematologic malignancies

HAEMATOLOGICA

IF7.9

2018-11-22

OAAI

Al-Zebeeby, Aoula; Vogler, Meike; Milani, Mateus; Richards, Caitlin; Alotibi, Ahoud; Greaves, Georgia; Dyer, Martin J. S.; Cohen, Gerald M.; Varadarajan, Shankar

BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-XL

CELL DEATH AND DIFFERENTIATION

IF15.4

2018-09-05

OAAI

Greaves, Georgia; Milani, Mateus; Butterworth, Michael; Carter, Rachel J.; Byrne, Dominic P.; Eyers, Patrick A.; Luo, Xu; Cohen, Gerald M.; Varadarajan, Shankar

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 细胞死亡的分子机制: 细胞死亡2018命名委员会的建议

CELL DEATH AND DIFFERENTIATION

IF15.4

2018-01-23

4.5K

OAAI

Galluzzi, Lorenzo; Vitale, Ilio; Aaronson, Stuart A.; Abrams, John M.; Adam, Dieter; Agostinis, Patrizia; Alnemri, Emad S.; Altucci, Lucia; Amelio, Ivano; Andrews, David W.; Annicchiarico-Petruzzelli, Margherita; Antonov, Alexey V.; Arama, Eli; Baehrecke, Eric H.; Barlev, Nickolai A.; Bazan, Nicolas G.; Bernassola, Francesca; Bertrand, Mathieu J. M.; Bianchi, Katiuscia; Blagosklonny, Mikhail V.; Blomgren, Klas; Borner, Christoph; Boya, Patricia; Brenner, Catherine; Campanella, Michelangelo; Candi, Eleonora; Carmona-Gutierrez, Didac; Cecconi, Francesco; Chan, Francis K. -M.; Chandel, Navdeep S.; Cheng, Emily H.; Chipuk, Jerry E.; Cidlowski, John A.; Ciechanover, Aaron; Cohen, Gerald M.; Conrad, Marcus; Cubillos-Ruiz, Juan R.; Czabotar, Peter E.; D'Angiolella, Vincenzo; Dawson, Ted M.; Dawson, Valina L.; De laurenzi, Vincenzo; De Maria, Ruggero; Debatin, Klaus-Michael; DeBerardinis, Ralph J.; Deshmukh, Mohanish; Di Daniele, Nicola; Di Virgilio, Francesco; Dixit, Vishva M.; Dixon, Scott J.; Duckett, Colin S.; Dynlacht, Brian D.; El-Deiry, Wafik S.; Elrod, John W.; Fimia, Gian Maria; Fulda, Simone; Garcia-Saez, Ana J.; Garg, Abhishek D.; Garrido, Carmen; Gavathiotis, Evripidis; Golstein, Pierre; Gottlieb, Eyal; Green, Douglas R.; Greene, Lloyd A.; Gronemeyer, Hinrich; Gross, Atan; Hajnoczky, Gyorgy; Hardwick, J. Marie; Harris, Isaac S.; Hengartner, Michael O.; Hetz, Claudio; Ichijo, Hidenori; Jaattela, Marja; Joseph, Bertrand; Jost, Philipp J.; Juin, Philippe P.; Kaiser, William J.; Karin, Michael; Kaufmann, Thomas; Kepp, Oliver; Kimchi, Adi; Kitsis, Richard N.; Klionsky, Daniel J.; Knight, Richard A.; Kumar, Sharad; Lee, Sam W.; Lemasters, John J.; Levine, Beth; Linkermann, Andreas; Lipton, Stuart A.; Lockshin, Richard A.; Lopez-Otin, Carlos; Lowe, Scott W.; Luedde, Tom; Lugli, Enrico; MacFarlane, Marion; Madeo, Frank; Malewicz, Michal; Malorni, Walter; Manic, Gwenola; Marine, Jean-Christophe; Martin, Seamus J.; Martinou, Jean-Claude; Medema, Jan Paul; Mehlen, Patrick; Meier, Pascal; Melino, Sonia; Miao, Edward A.; Molkentin, Jeffery D.; Moll, Ute M.; Munoz-Pinedo, Cristina; Nagata, Shigekazu; Nunez, Gabriel; Oberst, Andrew; Oren, Moshe; Overholtzer, Michael; Pagano, Michele; Panaretakis, Theocharis; Pasparakis, Manolis; Penninger, Josef M.; Pereira, David M.; Pervaiz, Shazib; Peter, Marcus E.; Piacentini, Mauro; Pinton, Paolo; Prehn, Jochen H. M.; Puthalakath, Hamsa; Rabinovich, Gabriel A.; Rehm, Markus; Rizzuto, Rosario; Rodrigues, Cecilia M. P.; Rubinsztein, David C.; Rudel, Thomas; Ryan, Kevin M.; Sayan, Emre; Scorrano, Luca; Shao, Feng; Shi, Yufang; Silke, John; Simon, Hans-Uwe; Sistigu, Antonella; Stockwell, Brent R.; Strasser, Andreas; Szabadkai, Gyorgy; Tait, Stephen W. G.; Tang, Daolin; Tavernarakis, Nektarios; Thorburn, Andrew; Tsujimoto, Yoshihide; Turk, Boris; Vanden Berghe, Tom; Vandenabeele, Peter; Heiden, Matthew G. Vander; Villunger, Andreas; Virgin, Herbert W.; Vousden, Karen H.; Vucic, Domagoj; Wagner, Erwin F.; Walczak, Henning; Wallach, David; Wang, Ying; Wells, James A.; Wood, Will; Yuan, Junying; Zakeri, Zahra; Zhivotovsky, Boris; Zitvogel, Laurence; Melino, Gerry; Kroemer, Guido

DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis

CELL DEATH & DISEASE

IF9.6

2017-01-12

OAAI

Milani, Mateus; Byrne, Dominic P.; Greaves, Georgia; Butterworth, Michael; Cohen, Gerald M.; Eyers, Patrick A.; Varadarajan, Shankar

BH3 profiling and a toolkit of BH3-mimetic drugs predict anti-apoptotic dependence of cancer cells

BRITISH JOURNAL OF CANCER

IF6.8

2016-03-08

OAAI

Butterworth, Michael; Pettitt, Andrew; Varadarajan, Shankar; Cohen, Gerald M.

High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia

LEUKEMIA

IF13.4

2016-02-29

OAAI

Lucas, C. M.; Milani, M.; Butterworth, M.; Carmell, N.; Scott, L. J.; Clark, R. E.; Cohen, G. M.; Varadarajan, S.

The transrepression arm of glucocorticoid receptor signaling is protective in mutant huntingtin-mediated neurodegeneration

CELL DEATH AND DIFFERENTIATION

IF15.4

2015-02-06

OAAI

Varadarajan, S.; Breda, C.; Smalley, J. L.; Butterworth, M.; Farrow, S. N.; Giorgini, F.; Cohen, G. M.

BIM-Mediated Membrane Insertion of the BAK Pore Domain Is an Essential Requirement for Apoptosis BIM介导的BAK孔结构域的膜插入是细胞凋亡的基本要求

CELL REPORTS

IF6.9

2013-10-01

OAAI

Weber, Kathrin; Harper, Nicholas; Schwabe, John; Cohen, Gerald M.

Evaluation and critical assessment of putative MCL-1 inhibitors

CELL DEATH AND DIFFERENTIATION

IF15.4

2013-07-05

OAAI

Varadarajan, S.; Vogler, M.; Butterworth, M.; Dinsdale, D.; Walensky, L. D.; Cohen, G. M.

Sabutoclax (BI97C1) and BI112D1, Putative Inhibitors of MCL-1, Induce Mitochondrial Fragmentation Either Upstream of or Independent of Apoptosis

NEOPLASIA

IF7.7

2013-05-01

OAAI

Varadarajan, Shankar; Butterworth, Michael; Wei, Jun; Pellecchia, Maurizio; Dinsdale, David; Cohen, Gerald M.

Molecular mechanisms involved in resistance of CLL cells towards ABT-737, a specific BCL-2 inhibitor (vol 290, pg 111, 2011)

TOXICOLOGY

IF4.6

2012-10-01

OAAI

Sun, Xiao-Ming; Dyer, Martin J.; Cohen, Gerald M.

A novel cellular stress response characterised by a rapid reorganisation of membranes of the endoplasmic reticulum 一种新的细胞应激反应，其特征是内质网膜的快速重组

CELL DEATH AND DIFFERENTIATION

IF15.4

2012-09-07

OAAI

Varadarajan, S.; Bampton, E. T. W.; Smalley, J. L.; Tanaka, K.; Caves, R. E.; Butterworth, M.; Wei, J.; Pellecchia, M.; Mitcheson, J.; Gant, T. W.; Dinsdale, D.; Cohen, G. M.

NOXA, a sensor of proteasome integrity, is degraded by 26S proteasomes by an ubiquitin-independent pathway that is blocked by MCL-1 NOXA是蛋白酶体完整性的传感器，通过泛素非依赖性途径被26s蛋白酶体降解，该途径被MCL-1阻断。

CELL DEATH AND DIFFERENTIATION

IF15.4

2012-02-24

OAAI

Craxton, A.; Butterworth, M.; Harper, N.; Fairall, L.; Schwabe, J.; Ciechanover, A.; Cohen, G. M.

Platelet toxicity induced by the BCL2-inhibitor ABT-263, a novel anti-cancer agent

TOXICOLOGY

IF4.6

2011-12-01

PREAI

Vogler, Meike; Hamali, Hassan A.; Bampton, Edward T. W.; Dinsdale, David; Sun, Xiao-Ming; Dyer, Martin J. S.; Goodall, Alison H.; Cohen, Gerald M.