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Mark Zak

roche holding usa
H指数:31
被引数:3,102

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An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections (vol 8, pg 1145, 2022)
2022-09-060
OAAI
Lung-restricted inhibition of Janus kinase 1 is effective in rodent models of asthma
2018-11-2132
PREAI
Fragment-Based Identification of Amides Derived from trans-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT)
2014-01-2245
PREAI
A Restricted Role for TYK2 Catalytic Activity in Human Cytokine Responses Revealed by Novel TYK2-Selective Inhibitors
2013-09-01116
OAAI
Structure-Based Discovery of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
2013-07-3184
PREAI
Structure-Based Identification of Ureas as Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors
2013-06-1369
PREAI
Identification of C-2 Hydroxyethyl Imidazopyrrolopyridines as Potent JAK1 Inhibitors with Favorable Physicochemical Properties and High Selectivity over JAK2
2013-05-3169
PREAI
Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2
2012-06-2875
PREAI
Identification of Imidazo-Pyrrolopyridines as Novel and Potent JAK1 Inhibitors
2012-06-1196
PREAI