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Identification of Small Molecule Inhibitors of RNase L by Fragment-Based Drug Discovery Tang, Jinle; Dong, Beihua; Liu, Ming; Liu, Shuyan; Niu, Xiaogang; Gaughan, Christina; Asthana, Abhishek; Zhou, Huan; Xu, Zhengshuang; Zhang, Guoliang; Silverman, Robert H.; Huang, Hao 分享 收藏
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Zika virus employs the host antiviral RNase L protein to support replication factory assembly Whelan, Jillian N.; Parenti, Nicholas A.; Hatterschide, Joshua; Renner, David M.; Li, Yize; Reyes, Hanako M.; Dong, Beihua; Perez, Erick R.; Silverman, Robert H.; Weiss, Susan R. 分享 收藏
SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes Li, Yize; Renner, David M.; Comar, Courtney E.; Whelan, Jillian N.; Reyes, Hanako M.; Cardenas-Diaz, Fabian Leonardo; Truitt, Rachel; Tan, Li Hui; Dong, Beihua; Alysandratos, Konstantinos Dionysios; Huang, Jessie; Palmer, James N.; Adappa, Nithin D.; Kohanski, Michael A.; Kotton, Darrell N.; Silverman, Robert H.; Yang, Wenli; Morrisey, Edward; Cohen, Noam A.; Weiss, Susan R. 分享 收藏
Suppressing PARylation by 2′,5′-oligoadenylate synthetase 1 inhibits DNA damage-induced cell death (vol 39, e101573, 2020) Kondratova, Anna; Cheon, HyeonJoo; Dong, Beihua; Holvey-Bates, Elise G.; Hasipek, Metis; Taran, Irina; Gaughan, Christina; Jha, Babal K.; Silverman, Robert H.; Stark, George R. 分享 收藏
A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency Daou, Salima; Talukdar, Manisha; Tang, Jinle; Dong, Beihua; Banerjee, Shuvojit; Li, Yize; Duffy, Nicole M.; Ogunjimi, Abiodun A.; Gaughan, Christina; Jha, Babal K.; Gish, Gerald; Tavernier, Nicolas; Mao, Daniel; Weiss, Susan R.; Huang, Hao; Silverman, Robert H.; Sicheri, Frank 分享 收藏
Suppressing PARylation by 2′,5′-oligoadenylate synthetase 1 inhibits DNA damage-induced cell death 2 ′,5 ′-寡腺苷酸合成酶1抑制PARylation抑制DNA损伤诱导的细胞死亡 Kondratova, Anna A.; Cheon, HyeonJoo; Dong, Beihua; Holvey-Bates, Elise G.; Hasipek, Metis; Taran, Irina; Gaughan, Christina; Jha, Babal K.; Silverman, Robert H.; Stark, George R. 分享 收藏
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OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug Banerjee, Shuvojit; Gusho, Elona; Gaughan, Christina; Dong, Beihua; Gu, Xiaorong; Holvey-Bates, Elise; Talukdar, Manisha; Li, Yize; Weiss, Susan R.; Sicheri, Frank; Saunthararajah, Yogen; Stark, George R.; Silverman, Robert H. 分享 收藏
Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line Li, Yize; Banerjee, Shuvojit; Goldstein, Stephen A.; Dong, Beihua; Gaughan, Christina; Rath, Sneha; Donovan, Jesse; Korennykh, Alexei; Silverman, Robert H.; Weiss, Susan R. 分享 收藏
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Murine AKAP7 Has a 2′,5′-Phosphodiesterase Domain That Can Complement an Inactive Murine Coronavirus ns2 Gene Gusho, Elona; Zhang, Rong; Jha, Babal K.; Thornbrough, Joshua M.; Dong, Beihua; Gaughan, Christina; Elliott, Ruth; Weiss, Susan R.; Silverman, Robert H. 分享 收藏
Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity Huang, Hao; Zeqiraj, Elton; Dong, Beihua; Jha, Babal Kant; Duffy, Nicole M.; Orlicky, Stephen; Thevakumaran, Neroshan; Talukdar, Manisha; Pillon, Monica C.; Ceccarelli, Derek F.; Wan, Leo C. K.; Juang, Yu-Chi; Mao, Daniel Y. L.; Gaughan, Christina; Brinton, Margo A.; Perelygin, Andrey A.; Kourinov, Igor; Guarne, Alba; Silverman, Robert H.; Sicheri, Frank 分享 收藏
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Homologous 2′,5′-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity Silverman, Robert H.; Zhang, Rong; Jha, Babal K.; Ogden, Kristen M.; Dong, Beihua; Elliott, Ruth; Zhao, Ling; Patton, John T.; Weiss, Susan R. 分享 收藏
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Homologous 2′,5′-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity Zhang, Rong; Jha, Babal K.; Ogden, Kristen M.; Dong, Beihua; Zhao, Ling; Elliott, Ruth; Patton, John T.; Silverman, Robert H.; Weiss, Susan R. 分享 收藏
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