Ming‐Hsun Ho

united states department of energy (doe)

15H指数

53论文数

650被引数

收录论文 12

发表时间

Discovery and Optimization of Pyrrolopyrimidines as Highly Potent; Selective and Brain-Penetrant LRRK2 Inhibitors 吡咯并嘧啶的发现与优化：作为高活性、高选择性及血脑屏障穿透性LRRK2抑制剂的研发

RSC Med. Chem.

IF3.6

2025-11-18

PREAI

Jeffrey Axten; Xiao Ding; Luigi Stasi; Baowei Zhao; Yingxia Sang; Ming-Hsun Ho; Lizhen Wang; Minhua Zhang; Xianjun Guo; Chengfang Tan; Xu Feng; Colin Edge; Klara L. Valko; Yi Li; Kelly Dong; Xiaoming Guan; Nico Zinn; F David Tattersall; Feng Ren; Dai-Shi Su; Alastair D Reith

Model-Based Virtual PK/PD Exploration and Machine Learning Approach to Define PK Drivers in Early Drug Discovery

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-02-20

PREAI

Chen, Emile P.; Dutta, Shayoni; Ho, Ming-Hsun; DeMartino, Michael P.

Applications of Model-Based Target Pharmacology Assessment in Defining Drug Design and DMPK Strategies: GSK Experiences

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-05-02

PREAI

Chen, Emile P.; Bondi, Robert W.; Zhang, Carolyn; Price, Daniel J.; Ho, Ming-Hsun; Armacost, Kira A.; DeMartino, Michael P.

Discovery of EBI-2511: A Highly Potent and Orally Active EZH2 Inhibitor for the Treatment of Non-Hodgkin's Lymphoma EBI-2511的发现: 一种高效和口服活性的EZH2抑制剂，用于治疗非霍奇金淋巴瘤

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2018-02-01

OAAI

Lu, Biao; Shen, Xiaodong; Zhang, Lei; Liu, Dong; Zhang, Caihua; Cao, Jingsong; Shen, Ru; Zhang, Jiayin; Wang, Dan; Wan, Hong; Xu, Zhibin; Ho, Ming-Hsun; Zhang, Minsheng; Zhang, Lianshan; He, Feng; Tao, Weikang

Toward Molecular Catalysts by Computer

ACCOUNTS OF CHEMICAL RESEARCH

IF17.7

2015-01-09

OAAI

Raugei, Simone; DuBois, Daniel L.; Rousseau, Roger; Chen, Shentan; Ho, Ming-Hsun; Bullock, R. Morris; Dupuis, Michel

Computing Free Energy Landscapes: Application to Ni-based Electrocatalysts with Pendant Amines for H2 Production and Oxidation

ACS CATALYSIS

IF13.1

2013-12-16

PREAI

Chen, Shentan; Ho, Ming-Hsun; Bullock, R. Morris; DuBois, Daniel L.; Dupuis, Michel; Rousseau, Roger; Raugei, Simone