Keith Nehrke - Publications, H-index & Citations

Keith Nehrke

University of North Carolina

40H指数

158论文数

4.5K被引数

收录论文 25

发表时间

The TWK-26/KCNK3 potassium channel and FLR-4 protein kinase coordinate nutrient absorption in the C. elegans intestine TWK-26/KCNK3钾通道和FLR-4蛋白激酶协调秀丽隐杆线虫肠道中的营养吸收

Genetics

IF5.1

2026-03-01

PREAI

Torzone, Sarah K.; Carroll, Trae; Breen, Peter C.; Cohen, Natalie R.; Simmons, Kaylee N.; VanDerMolen, Kylie R.; Schmidt, Annalee M.; Nehrke, Keith W.; Dowen, Robert H.

Tau clearance reverses touch neuron dysfunction in both young and aged C. elegansTau清除在年轻和年老C. elegans中逆转了触觉神经元的功能障碍

Journal of Alzheimer’s Disease

IF0

2025-11-24

PREAI

Trae A Carroll; Gail VW Johnson; Keith Nehrke

Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation Tau磷酸化通过FKBP8受体的调节抑制氧化应激诱导的线粒体自噬。

PLOS ONE

IF2.6

2025-01-03

OAAI

Isei, Michael O.; Crockett, Meredith; Chen, Emily; Rodwell-Bullock, Joel; Carroll, Trae; Girardi, Peter A.; Nehrke, Keith; Johnson, Gail V. W.

Manipulating mitochondrial pyruvate carrier function causes metabolic remodeling in corneal myofibroblasts that ameliorates fibrosis

REDOX BIOLOGY

IF11.9

2024-09-01

OAAI

Jeon, Kye-Im; Kumar, Ankita; Brookes, Paul S.; Nehrke, Keith; Huxlin, Krystel R.

Blocking Mitochondrial Pyruvate Transport Alters Corneal Myofibroblast Phenotype: A New Target for Treating Fibrosis

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2023-10-23

OAAI

Jeon, Kye-Im; Kumar, Ankita; Callan, Christine L.; DeMagistris, Margaret; MacRae, Scott; Nehrke, Keith; Huxlin, Krystel R.

Selective disruption of Drp1-independent mitophagy and mitolysosome trafficking by an Alzheimer's disease relevant tau modification in a novel Caenorhabditis elegans model 在新型秀丽隐杆线虫模型中，通过阿尔茨海默氏病相关的tau修饰选择性破坏Drp1-independent的线粒体自噬和线粒体溶酶体运输

GENETICS

IF5.1

2022-08-02

OAAI

Guha, Sanjib; Cheng, Anson; Carroll, Trae; King, Dennisha; Koren, Shon A.; Swords, Sierra; Nehrke, Keith; Johnson, Gail V. W.

Distinct roles for two Caenorhabditis elegans acid-sensing ion channels in an ultradian clock

ELIFE

IF0

2022-06-06

OAAI

Kaulich, Eva; Carroll, Trae; Ackley, Brian D.; Tang, Yi-Quan; Hardege, Iris; Nehrke, Keith; Schafer, William R.; Walker, Denise S.

Tau Post-Translational Modifications: Potentiators of Selective Vulnerability in Sporadic Alzheimer's Disease

BIOLOGY-BASEL

IF3.5

2021-10-15

OAAI

Carroll, Trae; Guha, Sanjib; Nehrke, Keith; Johnson, Gail V. W.

FNDC-1-mediated mitophagy and ATFS-1 coordinate to protect against hypoxia-reoxygenation

AUTOPHAGY

IF14.3

2021-01-19

OAAI

Lim, Yunki; Berry, Brandon; Viteri, Stephanie; McCall, Matthew; Park, Eun Chan; Rongo, Christopher; Brookes, Paul S.; Nehrke, Keith

Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic model

MOLECULAR NEURODEGENERATION

IF17.5

2020-11-09

OAAI

Guha, Sanjib; Fischer, Sarah; Johnson, Gail V. W.; Nehrke, Keith

Cardioprotection by nicotinamide mononucleotide (NMN): Involvement of glycolysis and acidic pH

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2018-08-01

OAAI

Nadtochiy, Sergiy M.; Wang, Yves T.; Nehrke, Keith; Munger, Josh; Brookes, Paul S.

Potential mechanisms linking SIRT activity and hypoxic 2-hydroxyglutarate generation: no role for direct enzyme (de)acetylation

BIOCHEMICAL JOURNAL

IF4.3

2017-08-10

OAAI

Nadtochiy, Sergiy M.; Wang, Yves T.; Zhang, Jimmy; Nehrke, Keith; Schafer, Xenia; Welle, Kevin; Ghaemmaghami, Sina; Munger, Josh; Brookes, Paul S.

The Slo(w) path to identifying the mitochondrial channels responsible for ischemic protection

BIOCHEMICAL JOURNAL

IF4.3

2017-06-09

OAAI

Smith, Charles Owen; Nehrke, Keith; Brookes, Paul S.

Acidic pH Is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-09-01

132

OAAI

Nadtochiy, Sergiy M.; Schafer, Xenia; Fu, Dragony; Nehrke, Keith; Munger, Joshua; Brookes, Paul S.

Cardiac Slo2.1 Is Required for Volatile Anesthetic Stimulation of K+ Transport and Anesthetic Preconditioning

ANESTHESIOLOGY

IF9.1

2016-05-01

OAAI

Wojtovich, Andrew P.; Smith, C. Owen; Urciuoli, William R.; Wang, Yves T.; Xia, Xiao-Ming; Brookes, Paul S.; Nehrke, Keith

Physiological consequences of complex II inhibition for aging, disease, and the mKATP channel

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

IF2.7

2013-05-01

OAAI

Wojtovich, Andrew P.; Smith, C. Owen; Haynes, Cole M.; Nehrke, Keith W.; Brookes, Paul S.

Bicarbonate modulates oxidative and functional damage in ischemia-reperfusion

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2013-02-01

OAAI

Queliconi, Bruno B.; Marazzi, Thire B. M.; Vaz, Sandra M.; Brookes, Paul S.; Nehrke, Keith; Augusto, Ohara; Kowaltowski, Alicia J.

Mitochondrial Fragmentation Leads to Intracellular Acidification in Caenorhabditis elegans and Mammalian Cells

MOLECULAR BIOLOGY OF THE CELL

IF2.7

2010-07-01

OAAI

Johnson, David; Nehrke, Keith

A Novel Mitochondrial KATP Channel Assay

CIRCULATION RESEARCH

IF16.2

2010-04-16

OAAI

Wojtovich, Andrew P.; Williams, David M.; Karcz, Marcin K.; Lopes, Coeli M. B.; Gray, Daniel A.; Nehrke, Keith W.; Brookes, Paul S.

Oscillatory transepithelial H+ flux regulates a rhythmic behavior in C-elegans

CURRENT BIOLOGY

IF7.5

2008-02-01

OAAI

Pfeiffer, Jason; Johnson, David; Nehrke, Keith

研究方向