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Natural products chlorotonils exert a complex antibacterial mechanism and address multiple targets 天然产物chlorotonils具有复杂的抗菌机制，并作用于多个靶点。 Deschner, Felix; Mostert, Dietrich; Daniel, Jan-Martin; Voltz, Alexander; Schneider, Dana Carina; Khangholi, Navid; Bartel, Jueurorgen; de Carvalho, Lais Pessanha; Brauer, Madita; Gorelik, Tatiana E.; Kleeberg, Christian; Risch, Timo; Haeckl, F. P. Jake; Benitez, Laura Herraiz; Andreas, Anastasia; Kany, Andreas Martin; Jezequel, Gwenaelle; Hofer, Walter; Muesken, Mathias; Held, Jana; Bischoff, Markus; Seemann, Ralf; Broetz-Oesterhelt, Heike; Schneider, Tanja; Sieber, Stephan; Mueller, Rolf; Herrmann, Jennifer 分享 收藏
Antibiotic-Polycationic Peptide Conjugation as an Effective Strategy to Overcome Daptomycin Resistance Rasheed, Sari; Umstaetter, Florian; Muehlberg, Eric; Beijer, Barbro; Hertlein, Tobias; Klika, Karel D.; Kleist, Christian; Werner, Julia; Domhan, Cornelius; Bingel, Mara; Mueller, Anna; Rausch, Marvin; Zimmermann, Stefan; Ohlsen, Knut; Haberkorn, Uwe; Koch, Marcus; Bischoff, Markus; Schneider, Tanja; Mueller, Rolf; Herrmann, Jennifer; Mier, Walter; Uhl, Philipp 分享 收藏
The Dual Mode of Antibacterial Action of the Synthetic Small Molecule DCAP Involves Lipid II Binding Ludwig, Kevin C.; Puls, Jan-Samuel; de Opitz, Cruz L. Matos; Innocenti, Paolo; Daniel, Jan-Martin; Bornikoel, Jan; Arts, Melina; Krannich, Sebastian; Straetener, Jan; Brajtenbach, Dominik; Henrichfreise, Beate; Sass, Peter; Mueller, Anna; Martin, Nathaniel I.; Brotz-Oesterhelt, Heike; Kubitscheck, Ulrich; Grein, Fabian; Schneider, Tanja 分享 收藏
Semisynthetic guanidino lipoglycopeptides with potent in vitro and in vivo antibacterial activity van Groesen, Emma; Mons, Elma; Kotsogianni, Ioli; Arts, Melina; Tehrani, Kamaleddin H. M. E.; Wade, Nicola; Lysenko, Vladyslav; Stel, Floor M.; Zwerus, Jordy T.; De Benedetti, Stefania; Bakker, Alexander; Chakraborty, Parichita; van der Stelt, Mario; Scheffers, Dirk-Jan; Gooskens, Jairo; Smits, Wiep Klaas; Holden, Kirsty; Gilmour, Peter S.; Willemse, Joost; Hitchcock, Christopher A.; van Hasselt, J. G. Coen; Schneider, Tanja; Martin, Nathaniel I. 分享 收藏
A classic antibiotic reimagined: Rationally designed bacitracin variants exhibit potent activity against vancomycin- resistant pathogens Buijs, Ned P.; Vlaming, Halana C.; Kotsogianni, Ioli; Arts, Melina; Willemse, Joost; Duan, Yunhao; Alexander, Francesca M.; Cochrane, Stephen A.; Schneider, Tanja; Martin, Nathaniel I. 分享 收藏
Synthesis of Bisindole Alkaloids and Their Mode of Action against Methicillin-Resistant Staphylococcus Aureus 双吲哚生物碱的合成及其对耐甲氧西林金黄色葡萄球菌的作用方式 Adeniyi, Emmanuel T.; Kruppa, Marco; De Benedetti, Stefania; Ludwig, Kevin C.; Krisilia, Violetta; Wassenberg, Tobias R.; Both, Melissa; Schneider, Tanja; Muller, Thomas J. J.; Kalscheuer, Rainer 分享 收藏
The MraY Inhibitor Muraymycin D2 and Its Derivatives Induce Enlarged Cells in Obligate Intracellular Chlamydia and Wolbachia and Break the Persistence Phenotype in Chlamydia Loeckener, Iris; Behrmann, Lara Vanessa; Reuter, Jula; Schiefer, Andrea; Kloeckner, Anna; Krannich, Sebastian; Otten, Christian; Moelleken, Katja; Ichikawa, Satoshi; Hoerauf, Achim; Schneider, Tanja; Pfarr, Kenneth M.; Henrichfreise, Beate 分享 收藏
Altering glycopeptide antibiotic biosynthesis through mutasynthesis allows incorporation of fluorinated phenylglycine residues Voitsekhovskaia, Irina; Ho, Y. T. Candace; Klatt, Christoph; Mueller, Anna; Machell, Daniel L.; Tan, Yi Jiun; Triesman, Maxine; Bingel, Mara; Schittenhelm, Ralf B.; Tailhades, Julien; Kulik, Andreas; Maier, Martin E.; Otting, Gottfried; Wohlleben, Wolfgang; Schneider, Tanja; Cryle, Max; Stegmann, Evi 分享 收藏
Biosynthesis of the corallorazines, a widespread class of antibiotic cyclic lipodipeptides Dreckmann, Teresa M.; Fritz, Lisa; Kaiser, Christian F.; Bouhired, Sarah M.; Wirtz, Daniel A.; Rausch, Marvin; Mueller, Anna; Schneider, Tanja; Koenig, Gabriele M.; Cruesemann, Max 分享 收藏
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Antibiotic-induced accumulation of lipid II synergizes with antimicrobial fatty acids to eradicate bacterial populations Sidders, Ashelyn E.; Kedziora, Katarzyna M.; Arts, Melina; Daniel, Jan-Martin; de Benedetti, Stefania; Beam, Jenna E.; Bui, Duyen T.; Parsons, Joshua B.; Schneider, Tanja; Rowe, Sarah E.; Conlon, Brian P. 分享 收藏
An NlpC/P60 protein catalyzes a key step in peptidoglycan recycling at the intersection of energy recovery, cell division and immune evasion in the intracellular pathogen Chlamydia trachomatis Reuter, Jula; Otten, Christian; Jacquier, Nicolas; Lee, Junghoon; Mengin-Lecreulx, Dominique; Loeckener, Iris; Kluj, Robert; Mayer, Christoph; Corona, Federico; Dannenberg, Julia; Aeby, Sebastien; Buehl, Henrike; Greub, Gilbert; Vollmer, Waldemar; Ouellette, Scot P.; Schneider, Tanja; Henrichfreise, Beate 分享 收藏
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Synergetic Antimicrobial Activity and Mechanism of ClotrimazoleLinked CO-Releasing Molecules Mendes, Sofia S.; Marques, Joana; Mesterhazy, Edit; Straetener, Jan; Arts, Melina; Pissarro, Teresa; Reginold, Jorgina; Berscheid, Anne; Bornikoel, Jan; Kluj, Robert M.; Mayer, Christoph; Oesterhelt, Filipp; Friaes, Sofia; Royo, Beatriz; Schneider, Tanja; Broetz-Oesterhelt, Heike; Romao, Carlos C.; Saraiva, Ligia M. 分享 收藏
Impacts of NaHCO3 on β-Lactam Binding to PBP2a Protein Variants Associated with the NaHCO3-Responsive versus NaHCO3-Non-Responsive Phenotypes Ersoy, Selvi C.; Chan, Liana C.; Yeaman, Michael R.; Chambers, Henry F.; Proctor, Richard A.; Ludwig, Kevin C.; Schneider, Tanja; Manna, Adhar C.; Cheung, Ambrose; Bayer, Arnold S. 分享 收藏
Visualizing the mode of action and supramolecular assembly of teixobactin analogues in Bacillus subtilis Morris, Michael A.; Vallmitjana, Alexander; Grein, Fabian; Schneider, Tanja; Arts, Melina; Jones, Chelsea R.; Nguyen, Betty T.; Hashemian, Mohammad H.; Malek, Melody; Gratton, Enrico; Nowick, James S. 分享 收藏
THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates Reithuber, Elisabeth; Wixe, Torbjorn; Ludwig, Kevin C.; Muller, Anna; Uvell, Hanna; Grein, Fabian; Lindgren, Anders E. G.; Muschiol, Sandra; Nannapaneni, Priyanka; Eriksson, Anna; Schneider, Tanja; Normark, Staffan; Henriques-Normark, Birgitta; Almqvist, Fredrik; Mellroth, Peter 分享 收藏
Biosynthesis and Mechanism of Action of the Cell Wall Targeting Antibiotic Hypeptin Wirtz, Daniel A.; Ludwig, Kevin C.; Arts, Melina; Marx, Carina E.; Krannich, Sebastian; Barac, Paul; Kehraus, Stefan; Josten, Michaele; Henrichfreise, Beate; Mueller, Anna; Koenig, Gabriele M.; Peoples, Aaron J.; Nitti, Anthony; Spoering, Amy L.; Ling, Losee L.; Lewis, Kim; Cruesemann, Max; Schneider, Tanja 分享 收藏
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