未登录.png)
分享.png)
收藏分享 收藏 分享 收藏 分享 收藏 Discovery and Preclinical Characterization of Fulacimstat (BAY 1142524), a Potent and Selective Chymase Inhibitor As a New Profibrinolytic Approach for Safe Thrombus Resolution
Fuerstner, Chantal; Ackerstaff, Jens; Meier, Heinrich; Straub, Alexander; Mittendorf, Joachim; Schamberger, Jens; Schaefer, Martina; Boerngen, Kirsten; Joerissen, Hannah; Zubov, Dmitry; Zimmermann, Katja; Tersteegen, Adrian; Geiss, Volker; Hartmann, Elke; Albrecht-Kuepper, Barbara; D'Orleans-Juste, Pedro; Lapointe, Catherine; Vincent, Laurence; Heitmeier, Stefan; Tinel, Hanna 分享 收藏 分享 收藏 Discovery of BAY 2413555, First Selective Positive Allosteric Modulator of the M2 Receptor to Restore Cardiac Autonomic BalanceVakalopoulos, Alexandros; Basting, Daniel; Brechmann, Markus; Teller, Henrik; Boultadakis Arapinis, Melissa; Straub, Alexander; Mittendorf, Joachim; Meininghaus, Mark; Mueller, Thomas; Nowak-Reppel, Katrin; Schaefer, Martina; Wittwer, Matthias; Kullmann, Maximilian; Terjung, Carsten; Lang, Dieter; Poethko, Thorsten; Marquardt, Tobias; Freudenberger, Till; Mondritzki, Thomas; Huser, Jorg; Heckmann, Michael; Tinel, Hanna 分享 收藏 Discovery of BAY-405: An Azaindole-Based MAP4K1 Inhibitor for the Enhancement of T-Cell Immunity against CancerMowat, Jeffrey; Carretero, Rafael; Leder, Gabriele; Font, Nuria Aiguabella; Neuhaus, Roland; Berndt, Sandra; Guenther, Judith; Friberg, Anders; Schaefer, Martina; Briem, Hans; Raschke, Marian; Ondozabal, Hideki Miyatake; Buchmann, Bernd; Boemer, Ulf; Kreft, Bertolt; Hartung, Ingo V.; Offringa, Rienk 分享 收藏 分享 收藏 Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839IRAK4抑制剂BAY1834845 (Zabedosertib) 和BAY1830839的发现Bothe, Ulrich; Guenther, Judith; Nubbemeyer, Reinhard; Siebeneicher, Holger; Ring, Sven; Boemer, Ulf; Peters, Michaele; Rausch, Alexandra; Denner, Karsten; Himmel, Herbert; Sutter, Andreas; Terebesi, Ildiko; Lange, Martin; Wengner, Antje M.; Guimond, Nicolas; Thaler, Tobias; Platzek, Johannes; Eberspaecher, Uwe; Schaefer, Martina; Steuber, Holger; Zollner, Thomas M.; Steinmeyer, Andreas; Schmidt, Nicole 分享 收藏 分享 收藏 Changing for the Better: Discovery of the Highly Potent and Selective CDK9 Inhibitor VIP152 Suitable for Once Weekly Intravenous Dosing for the Treatment of CancerLuecking, Ulrich; Kosemund, Dirk; Boehnke, Niels; Lienau, Philip; Siemeister, Gerhard; Denner, Karsten; Bohlmann, Rolf; Briem, Hans; Terebesi, Ildiko; Bomer, Ulf; Schaefer, Martina; Ince, Stuart; Mumberg, Dominik; Scholz, Arne; Izumi, Raquel; Hwang, Stuart; von Nussbaum, Franz 分享 收藏 Imitation, adaptation, or local emergency? - A cross-country comparison of social innovations for sustainable consumption in Brazil, Germany, and IranSchaefer, Martina; de Figueiredo, Marina Dantas; Iran, Samira; Jaeger-Erben, Melanie; Silva, Minelle E.; Lazaro, Jose Carlos; Meissner, Magdalena 分享 收藏 Discovery and Characterization of BAY 1214784, an Orally Available Spiroindoline Derivative Acting as a Potent and Selective Antagonist of the Human Gonadotropin-Releasing Hormone Receptor as Proven in a First-In-Human Study in Postmenopausal WomenPanknin, Olaf; Wagenfeld, Andrea; Bone, Wilhelm; Bender, Eckhard; Nowak-Reppel, Katrin; Fernandez-Montalvan, Amaury E.; Nubbemeyer, Reinhard; Baeurle, Stefan; Ring, Sven; Schmees, Norbert; Prien, Olaf; Schaefer, Martina; Friedrich, Christian; Zollner, Thomas M.; Steinmeyer, Andreas; Mueller, Thomas; Langer, Gernot 分享 收藏 Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monotherapy and in Combination Treatments in Preclinical Tumor ModelsLuecking, Ulrich; Wortmann, Lars; Wengner, Antje M.; Lefranc, Julien; Lienau, Philip; Briem, Hans; Siemeister, Gerhard; Boemer, Ulf; Denner, Karsten; Schaefer, Martina; Koppitz, Marcus; Eis, Knut; Bartels, Florian; Bader, Benjamin; Bone, Wilhelm; Moosmayer, Dieter; Holton, Simon J.; Eberspaecher, Uwe; Grudzinska-Goebel, Joanna; Schatz, Christoph; Deeg, Gesa; Mumberg, Dominik; von Nussbaum, Franz 分享 收藏 分享 收藏 Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent, and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels in VivoWortmann, Lars; Lindenthal, Bernhard; Muhn, Peter; Walter, Alexander; Nubbemeyer, Reinhard; Heldmann, Dieter; Sobek, Lothar; Morandi, Federica; Schrey, Anna K.; Moosmayer, Dieter; Guenther, Judith; Kuhnke, Joachim; Koppitz, Marcus; Luecking, Ulrich; Roehn, Ulrike; Schaefer, Martina; Nowak-Reppel, Katrin; Kuehne, Ronald; Weinmann, Hilmar; Langer, Gernot 分享 收藏 分享 收藏 分享 收藏 分享 收藏 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
