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收藏Design, synthesis, and biological evaluation of potent c-Met inhibitors
D'Angelo, Noel D.; Bellon, Steven F.; Booker, Shon K.; Cheng, Yuan; Coxon, Angela; Dominguez, Celia; Fellows, Ingrid; Hoffman, Douglas; Hungate, Randall; Kaplan-Lefko, Paula; Lee, Matthew R.; Li, Chun; Liu, Longbin; Rainbeau, Elizabeth; Reider, Paul J.; Rex, Karen; Siegmund, Aaron; Sun, Yaxiong; Tasker, Andrew S.; Xi, Ning; Xu, Shimin; Yang, Yajing; Zhang, Yihong; Burgess, Teresa L.; Dussault, Isabelle; Kim, Tae-Seong 分享 收藏 An integrated high-throughput screening approach for purification of solid organic compounds by trituration and crystallization in solventsTan, Helming; Reed, Maggie; Gahm, Kyung H.; King, Tony; Seran, Mina Dilmeghani; Bostick, Tracy; Luu, Van; Semin, David; Cheetham, Janet; Larsen, Rob; Martinelli, Mike; Reider, Paul 分享 收藏 Identification of a nonpeptidic and conformationally restricted bradykinin B1 receptor antagonist with anti-inflammatory activityD'Amico, Derin C.; Aya, Toshi; Human, Jason; Fotsch, Christopher; Chen, Jian Jeffrey; Biswas, Kaustav; Riahi, Bobby; Norman, Mark H.; Willoughby, Christopher A.; Hungate, Randall; Reider, Paul J.; Biddlecome, Gloria; Lester-Zeiner, Dianna; Van Staden, Carlo; Johnson, Eileen; Kamassah, Augustus; Arik, Leyla; Wang, Judy; Viswanadhan, Vellarkad N.; Groneberg, Robert D.; Zhan, James; Suzuki, Hideo; Toro, Andras; Mareska, David A.; Clarke, David E.; Harvey, Darren M.; Burgess, Laurence E.; Laird, Ellen R.; Askew, Benny; Ng, Gordon 分享 收藏 A practical synthesis of 2-((1H-pyrrolo[2,3-b]pyridine-4-yl)methylamino)-5-fluoronicotinic acidWang, X; Zhi, B; Baum, J; Chen, Y; Crockett, R; Huang, L; Eisenberg, S; Ng, J; Larsen, R; Martinelli, M; Reider, P 分享 收藏 New air-stable catalysts for general and efficient Suzuki-Miyaura cross-coupling reactions of heteroaryl chloridesGuram, AS; King, AO; Allen, JG; Wang, XH; Schenkel, LB; Chan, J; Bunel, EE; Faul, MM; Larsen, RD; Martinelli, MJ; Reider, PJ 分享 收藏 分享 收藏 分享 收藏 An efficient synthesis of an αvβ3 antagonistYasuda, N; Hsiao, Y; Jensen, MS; Rivera, NR; Yang, CH; Wells, KM; Yau, J; Palucki, M; Tan, LS; Dormer, PG; Volante, RP; Hughes, DL; Reider, PJ 分享 收藏 分享 收藏 分享 收藏 Efficient synthesis of NK1 receptor antagonist aprepitant using a crystallization-induced diastereoselective transformationBrands, KMJ; Payack, JF; Rosen, JD; Nelson, TD; Candelario, A; Huffman, MA; Zhao, MM; Li, J; Craig, B; Song, ZGJ; Tschaen, DM; Hansen, K; Devine, PN; Pye, PJ; Rossen, K; Dormer, PG; Reamer, RA; Welch, CJ; Mathre, DJ; Tsou, NN; McNamara, JM; Reider, PJ 分享 收藏 Highly regioselective Friedlander annulations with unmodified ketones employing novel amine catalysts: Syntheses of 2-substituted quinolines, 1,8-naphthyridines, and related heterocyclesDormer, PG; Eng, KK; Farr, RN; Humphrey, GR; McWilliams, JC; Reider, PJ; Sager, JW; Volante, RP 分享 收藏 分享 收藏 Practical asymmetric synthesis of aprepitant, a potent human NK-1 receptor antagonist, via a stereoselective Lewis acid-catalyzed trans acetalization reactionZhao, MM; McNamara, JM; Ho, GJ; Emerson, KM; Song, ZGJ; Tschaen, DM; Brands, KMJ; Dolling, UH; Grabowski, EJJ; Reider, PJ; Cottrell, IF; Ashwood, MS; Bishop, BC 分享 收藏 An unexpected [1,5]-H shift in the synthesis of nitroanilines (vol 4, pg 439, 2002)Davies, IW; Marcoux, JF; Taylor, JDO; Dormer, PG; Deeth, RJ; Marcotte, FA; Hughes, DL; Reider, PJ 分享 收藏 Development of a new and practical route to chiral 3,4-disubstituted cyclopentanones: Symmetric alkylation and intramolecular cyclopropanation as key C-C bond-forming stepsPalucki, M; Um, JM; Yasuda, N; Conlon, DA; Tsay, FR; Hartner, FW; Hsiao, Y; Marcune, B; Karady, S; Hughes, DL; Dormer, PG; Reider, PJ 分享 收藏 Asymmetric synthesis of 1,2,3-trisubstituted cyclopentanes and cyclohexanes as key components of substance P antagonistsKuethe, JT; Wong, A; Wu, J; Davies, IW; Dormer, PG; Welch, CJ; Hillier, MC; Hughes, DL; Reider, PJ 分享 收藏 分享 收藏 Designed ligands as probes for the catalytic binding mode in mo-catalyzed asymmetric allylic alkylationTrost, BM; Dogra, K; Hachiya, I; Emura, T; Hughes, DL; Krska, S; Reamer, RA; Palucki, M; Yasuda, N; Reider, PJ 分享 收藏 
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