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收藏Discovery and Optimization of 4,5-Diarylisoxazoles as Potent Dual Inhibitors of Pyruvate Dehydrogenase Kinase and Heat Shock Protein 90 (vol 57, pg 9832, 2014)
Meng, Tao; Zhang, Dadong; Xie, Zuoquan; Yu, Ting; Wu, Shuchao; Wyder, Lorenza; Regenass, Urs; Hilpert, Kurt; Huang, Min; Geng, Meiyu; Shen, Jingkang 分享 收藏 4-((R)-2-{[6-((S)-3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl)piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than ClopidogrelCaroff, Eva; Hubler, Francis; Meyer, Emmanuel; Renneberg, Dorte; Gnerre, Carmela; Treiber, Alexander; Rey, Markus; Hess, Patrick; Steiner, Beat; Hilpert, Kurt; Riederer, Markus A. 分享 收藏 Discovery and Optimization of 4,5-Diarylisoxazoles as Potent Dual Inhibitors of Pyruvate Dehydrogenase Kinase and Heat Shock Protein 90Meng, Tao; Zhang, Dadong; Xie, Zuoquan; Yu, Ting; Wu, Shuchao; Wyder, Lorenza; Regenass, Urs; Hilpert, Kurt; Huang, Min; Geng, Meiyu; Shen, Jingkang 分享 收藏 Identification of 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968), a Potent, Selective, and Orally Bioavailable Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTH2) AntagonistFretz, Heinz; Valdenaire, Anja; Pothier, Julien; Hilpert, Kurt; Gnerre, Carmela; Peter, Oliver; Leroy, Xavier; Riederer, Markus A. 分享 收藏 分享 收藏 分享 收藏 分享 收藏 DESIGN AND SYNTHESIS OF POTENT AND HIGHLY SELECTIVE THROMBIN INHIBITORSHILPERT, K; ACKERMANN, J; BANNER, DW; GAST, A; GUBERNATOR, K; HADVARY, P; LABLER, L; MULLER, K; SCHMID, G; TSCHOPP, TB; VANDEWATERBEEMD, H 分享 收藏 
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