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Genomic epidemiology of Plasmodium knowlesi reveals putative genetic drivers of adaptation in Malaysia Westaway, Jacob A. F.; Diez Benavente, Ernest; Auburn, Sarah; Kucharski, Michal; Aranciaga, Nicolas; Nayak, Sourav; William, Timothy; Rajahram, Giri S.; Piera, Kim A.; Braima, Kamil; Tan, Angelica F.; Alaza, Danshy A.; Barber, Bridget E.; Drakeley, Chris; Amato, Roberto; Sutanto, Edwin; Trimarsanto, Hidayat; Jelip, Jenarun; Anstey, Nicholas M.; Bozdech, Zbynek; Field, Matthew; Grigg, Matthew J. 分享 收藏
Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background Nayak, Sourav; Peto, Thomas J.; Kucharski, Michal; Tripura, Rupam; Callery, James J.; Huy, Duong Tien Quang; Gendrot, Mathieu; Lek, Dysoley; Nghia, Ho Dang Trung; van der Pluijm, Rob W.; Dong, Nguyen; Long, Le Thanh; Vongpromek, Ranitha; Rekol, Huy; Chau, Nguyen Hoang; Miotto, Olivo; Mukaka, Mavuto; Dhorda, Mehul; von Seidlein, Lorenz; Imwong, Mallika; Roca, Xavier; Day, Nicholas P. J.; White, Nicholas J.; Dondorp, Arjen M.; Bozdech, Zbynek 分享 收藏
Identification of complex Plasmodium falciparum genetic backgrounds circulating in Africa: a multicountry genomic epidemiology analysis 鉴定非洲流行的复杂恶性疟原虫遗传背景：一项多国基因组流行病学分析 Miotto, Olivo; Hamid, Muzamil M. Abdel; Adam, Ishag; Apinjoh, Tobias; Awandare, Gordon A.; Bejon, Philip; Bertin, Gwladys I.; Bouyou-Akotet, Marielle; Claessens, Antoine; Conway, David J.; D'Alessandro, Umberto; Diakite, Mahamadou; Djimde, Abdoulaye; Dondorp, Arjen M.; Duffy, Patrick; Fairhurst, Rick M.; Fanello, Caterina I.; Ghansah, Anita; Ishengoma, Deus S.; Lawniczak, Mara; Maiga-Ascofare, Oumou; Auburn, Sarah; Rosanas-Urgell, Anna; Wasakul, Varanya; White, Nina F. D.; Almagro-Garcia, Jacob; Pearson, Richard D.; Goncalves, Sonia; Ariani, Cristina; Bozdech, Zbynek; Hamilton, William L.; Simpson, Victoria; Kwiatkowski, Dominic P. 分享 收藏
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The artemisinin-induced dormant stages of Plasmodium falciparum exhibit hallmarks of cellular quiescence/senescence and drug resilience (vol 15, 7485, 2024) Tripathi, Jaishree; Stoklasa, Michal; Nayak, Sourav; Low, Kay En; Lee, Erica Qian Hui; Tien, Quang Huy Duong; Renia, Laurent; Malleret, Benoit; Bozdech, Zbynek 分享 收藏
Inhibition of falcilysin from Plasmodium falciparum by interference with its closed-to-open dynamic transition Lin, Jianqing; Yan, Xinfu; Chung, Zara; Liew, Chong Wai; El Sahili, Abbas; Pechnikova, Evgeniya V.; Preiser, Peter R.; Bozdech, Zbynek; Gao, Yong-Gui; Lescar, Julien 分享 收藏
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Identification of an inhibitory pocket in falcilysin provides a new avenue for malaria drug development Wirjanata, Grennady; Lin, Jianqing; Dziekan, Jerzy Michal; El Sahili, Abbas; Chung, Zara; Tjia, Seth; Zulkifli, Nur Elyza Binte; Boentoro, Josephine; Tham, Roy; Jia, Lai Si; Go, Ka Diam; Yu, Han; Partridge, Anthony; Olsen, David; Prabhu, Nayana; Sobota, Radoslaw M.; Nordlund, Par; Lescar, Julien; Bozdech, Zbynek 分享 收藏
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Sterile protection against P. vivax malaria by repeated blood stage infection in the Aotus monkey model Obaldia III, Nicanor; Da Silva Filho, Joao Luiz; Nunez, Marlon; Glass, Katherine A.; Oulton, Tate; Achcar, Fiona; Wirjanata, Grennady; Duraisingh, Manoj; Felgner, Philip; Tetteh, Kevin K. A.; Bozdech, Zbynek; Otto, Thomas D.; Marti, Matthias 分享 收藏
Plasmodium falciparum Eukaryotic Translation Initiation Factor 3 is Stabilized by Quinazoline-Quinoline Bisubstrate Inhibitors 喹唑啉-喹啉双底物抑制剂稳定恶性疟原虫真核翻译起始因子3 Dobrescu, Irina; Hammam, Elie; Dziekan, Jerzy M.; Claes, Aurelie; Halby, Ludovic; Preiser, Peter; Bozdech, Zbynek; Arimondo, Paola B.; Scherf, Artur; Nardella, Flore 分享 收藏
Genomic, transcriptomic, and metabolomic analysis of Oldenlandia corymbosa reveals the biosynthesis and mode of action of anti-cancer metabolites Julca, Irene; Mutwil-Anderwald, Daniela; Manoj, Vaishnervi; Khan, Zahra; Lai, Soak Kuan; Yang, Lay. K. K.; Beh, Ing. T. T.; Dziekan, Jerzy; Lim, Yoon. P. P.; Lim, Shen. K. K.; Low, Yee. W. W.; Lam, Yuen. I. I.; Tjia, Seth; Mu, Yuguang; Tan, Qiao. W. W.; Nuc, Przemyslaw; Choo, Le. M. M.; Khew, Gillian; Shining, Loo; Kam, Antony; Tam, James. P. P.; Bozdech, Zbynek; Schmidt, Maximilian; Usadel, Bjoern; Kanagasundaram, Yoganathan; Alseekh, Saleh; Fernie, Alisdair; Li, Hoi. Y. Y.; Mutwil, Marek 分享 收藏
Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target Wagner, Matthias Paulus; Formaglio, Pauline; Gorgette, Olivier; Dziekan, Jerzy Michal; Huon, Christele; Berneburg, Isabell; Rahlfs, Stefan; Barale, Jean-Christophe; Feinstein, Sheldon I.; Fisher, Aron B.; Menard, Didier; Bozdech, Zbynek; Amino, Rogerio; Touqui, Lhousseine; Chitnis, Chetan E. 分享 收藏
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Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response Zhu, Lei; van der Pluijm, Rob W.; Kucharski, Michal; Nayak, Sourav; Tripathi, Jaishree; White, Nicholas J.; Day, Nicholas P. J.; Faiz, Abul; Phyo, Aung Pyae; Amaratunga, Chanaki; Lek, Dysoley; Ashley, Elizabeth A.; Nosten, Francois; Smithuis, Frank; Ginsburg, Hagai; von Seidlein, Lorenz; Lin, Khin; Imwong, Mallika; Chotivanich, Kesinee; Mayxay, Mayfong; Dhorda, Mehul; Hoang Chau Nguyen; Thuy Nhien Thanh Nguyen; Miotto, Olivo; Newton, Paul N.; Jittamala, Podjanee; Tripura, Rupam; Pukrittayakamee, Sasithon; Peto, Thomas J.; Tran Tinh Hien; Dondorp, Arjen M.; Bozdech, Zbynek 分享 收藏
Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival Mok, Sachel; Stokes, Barbara H.; Gnaedig, Nina F.; Ross, Leila S.; Yeo, Tomas; Amaratunga, Chanaki; Allman, Erik; Solyakov, Lev; Bottrill, Andrew R.; Tripathi, Jaishree; Fairhurst, Rick M.; Llinas, Manuel; Bozdech, Zbynek; Tobin, Andrew B.; Fidock, David A. 分享 收藏
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