未登录Loss of nsp14-exonuclease activity impairs the replication, proofreading, fitness, and pathogenesis of SARS-CoV-2nsp14-外切核酸酶活性的丧失损害了SARS-CoV-2的复制、校对、适应性和致病性
Anderson-Daniels, Jordan; Diefenbacher, Meghan V.; Yount, Boyd L.; Meganck, Rita M.; Tse, Longping V.; Burke, Kaitlyn N.; Miranda, Hector A.; Scobey, D. Trevor; Lu, Xiaotao; Stevens, Laura; Dinnon III, Kenneth H.; Chapman, Nathaniel S.; Pajon, Camryn; Powers, John M.; Nguyen, Cameron; Graham, Rachel L.; Heaton, Nicholas S.; Baric, Ralph S.; Denison, Mark R.; Sheahan, Timothy P. .png)
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收藏The oral nucleoside prodrug GS-5245 is efficacious against SARS-CoV-2 and other endemic, epidemic, and enzootic coronavirusesMartinez, David R.; Moreira, Fernando R.; Catanzaro, Nicholas J.; Diefenbacher, Meghan V.; Zweigart, Mark R.; Gully, Kendra L.; De la Cruz, Gabriela; Brown, Ariane J.; Adams, Lily E.; Yount, Boyd; Baric, Thomas J.; Mallory, Michael L.; Conrad, Helen; May, Samantha R.; Dong, Stephanie; Scobey, D. Trevor; Nguyen, Cameron; Montgomery, Stephanie A.; Perry, Jason K.; Babusis, Darius; Barrett, Kimberly T.; Nguyen, Anh-Hoa; Nguyen, Anh-Quan; Kalla, Rao; Bannister, Roy; Feng, Joy Y.; Cihlar, Tomas; Baric, Ralph S.; Mackman, Richard L.; Bilello, John P.; Schaefer, Alexandra; Sheahan, Timothy P. 分享 收藏 A Multitrait Locus Regulates Sarbecovirus PathogenesisSchafer, Alexandra; Leist, Sarah R.; Gralinski, Lisa E.; Martinez, David R.; Winkler, Emma S.; Okuda, Kenichi; Hawkins, Padraig E.; Gully, Kendra L.; Graham, Rachel L.; Scobey, D. Trevor; Bell, Timothy A.; Hock, Pablo; Shaw, Ginger D.; Loome, Jennifer F.; Madden, Emily A.; Anderson, Elizabeth; Baxter, Victoria K.; Taft-Benz, Sharon A.; Zweigart, Mark R.; May, Samantha R.; Dong, Stephanie; Clark, Matthew; Miller, Darla R.; Lynch, Rachel M.; Heise, Mark T.; Tisch, Roland; Boucher, Richard C.; de Villena, Fernando Pardo Manuel; Montgomery, Stephanie A.; Diamond, Michael S.; Ferris, Martin T.; Baric, Ralph S. 分享 收藏 
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