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收藏分享 收藏 分享 收藏 分享 收藏 分享 收藏 AWT030: a first-in-class bi-functional IL-21 fusion protein selectively activates tumor infiltrated CD8 T cells and suppresses Treg cells
Ye, Fan; Huang, Jianing; Chen, Sandra; Li, Ella; Jiang, Jenny; Lin, Hanna; Hua, Michael; Huang, Danny; Huang, Zoey; Kwan, Joyce; Cheng, Lili; Zhong, Ziyang 分享 收藏 LINC02870 facilitates SNAIL translation to promote hepatocellular carcinoma progressionGuo, Mengya; Zhuang, Hao; Huang, Jianing; Shao, Xiaowen; Bai, Nan; Li, Minghe; Niu, Minmin; Wei, Wen; Sun, Li; Li, Yongmei; Qiang, Zhaoyan 分享 收藏 A HIGHLY POTENT ANTI-LAG-3-IL-2C THAT SELECTIVELY TARGETS TUMOR-SPECIFIC CD8+ T CELLSHuang, Zoey; Huang, Jianing; Ye, Fan; Chen, Sandra; Huang, Danny; Hua, Michael; Li, Ella; Jiang, Jenny; Lin, Hanna; Shi, Shirley; Yue, Bella; He, Henry; Yang, Mingxing; Fu, Qiang; Zhong, Ziyang 分享 收藏 EXENOKINE-2: A HALF-LIFE EXTENDED NO-α-IL-2 WITH IMPROVED PRECLINICAL PHARMACOLOGICAL PROPERTIES SUPPORTS FIRST-IN-HUMAN CLINICAL DEVELOPMENTCheng, Lili; Ye, Fan; Chen, Sandra; Huang, Jianing; Jiang, Jenny; He, Henry; Shi, Shirley; Yang, Mingxing; Fu, Qiang; Xia, Ark; Hong, Yudan; Xin, Wang; Yuan, Karen; Liu, Hongchuan; Feng, Hui; Liu, Eugene; Zhong, Ziyang 分享 收藏 A SAFE AND HIGHLY POTENT PD-1-IL-2 FUSION (AWT020) THAT DECOUPLES THE EFFICACY AND TOXICITY OF IL-2 THERAPYYe, Fan; Huang, Zoey; Cheng, Lili; Huang, Jianing; Chen, Sandra; Hua, Michael; Huang, Danny; Li, Ella; Jiang, Jenny; Lin, Hanna; Wang, Xin; Yue, Bella; Shi, Shirley; He, Henry; Yan, Karen; Lu, Binfeng; Zhong, Ziyang 分享 收藏 分享 收藏 分享 收藏 Development of small molecule direct AMPK activators for the treatment of cancerHitoshi, Yasumichi; Jenkins, Yonchu; Li, Yingwu; Sampang, Elmer; Xu, Xiang; Dong, Guodong; Huang, Jianing; Lin, Nan; Goff, Dane; Shaw, Simon; Boralsky, Luke; Singh, Rajinder; Issakani, Sarkiz D.; Payan, Donald G. 分享 收藏 2a, a novel curcumin analog, sensitizes cisplatin-resistant A549 cells to cisplatin by inhibiting thioredoxin reductase concomitant oxidative stress damageZhou, Binhua; Huang, Jianing; Zuo, Yinglin; Li, Baojian; Guo, Qiang; Cui, Baicheng; Shao, Weiyan; Du, Jun; Bu, Xianzhang 分享 收藏 Synthesis, cytotoxicity of new 4-arylidene curcumin analogues and their multi-functions in inhibition of both NF-κB and Akt signallingZuo, Yinglin; Huang, Jianing; Zhou, Binhua; Wang, Shuni; Shao, Weiyan; Zhu, Cuige; Lin, Li; Wen, Gesi; Wang, Hongyang; Du, Jun; Bu, Xianzhang 分享 收藏 Synthesis and Identification of New 4-Arylidene Curcumin Analogues as Potential Anticancer Agents Targeting Nuclear Factor-κB Signaling PathwayQiu, Xu; Du, Yuhong; Lou, Bin; Zuo, Yinglin; Shao, Weiyan; Huo, Yingpeng; Huang, Jianing; Yu, Yanjun; Zhou, Binhua; Du, Jun; Fu, Haian; Bu, Xianzhang 分享 收藏 分享 收藏 A class of small molecules that inhibit TNFα-induced survival and death pathways via prevention of interactions between TNFαRI, TRADD and RIP1Gururaja, Tarikere L.; Yung, Stephanie; Ding, Rongxian; Huang, Jianing; Zhou, Xiulan; McLaughlin, John; Daniel-Tssakani, Sarkiz; Sing, Rajinder; Cooper, Robin D. G.; Payan, Donald G.; Masuda, Esteban; Kinoshita, Taisei 分享 收藏 R-253 disrupts microtubule networks in multiple tumor cell linesGururaja, Tarikere L.; Goff, Dane; Kinoshita, Taisei; Goldstein, Eileen; Yung, Stephanie; McLaughlin, John; Pali, Erlina; Huang, Jianing; Singh, Rajinder; Daniel-Issakani, Sarkiz; Hitoshi, Yasumichi; Cooper, R. D. G.; Payan, Donald G. 分享 收藏 Critical role of the ubiquitin ligase activity of UHRF1, a nuclear RING finger protein, in tumor cell growthJenkins, Y; Markovtsov, V; Lang, W; Sharma, P; Pearsall, D; Warner, J; Franci, C; Huang, B; Huang, JN; Yam, GC; Vistan, JP; Pali, E; Vialard, J; Janicot, M; Lorens, JB; Payan, DG; Hitoshi, Y 分享 收藏 
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