Michael J. Pikal - Publications, H-index & Citations

Michael J. Pikal

University of Connecticut

71H指数

260论文数

1.6W被引数

收录论文 74

发表时间

Evaluation of a Raman Chemometric Method for Detecting Protein Structural Conformational Changes in Solution

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2023-02-01

PREAI

Fontana, Lauren; Anderson, Carl; Bogner, Robin; Pikal, Michael

AAPS PHARMSCITECH

IF4

2023-01-26

OAAI

Ganguly, Arnab; Hardwick, Lisa; Tchessalov, Serguei; Nail, Steven L.; Dixon, Dan; Kanka, Frank; Guidinas, Anthony; Thompson, T. N.; Reiter, Cindy; Yusoff, Zakaria; Tharp, Ted; Azzarella, Joseph; Sharma, Prerona; Kazarin, Petr; Alexeenko, Alina; Pikal, Michael J.

Evaluation of Predictors of Protein Relative Stability Obtained by \Solid-State Hydrogen/Deuterium Exchange Monitored by FTIR (vol 374, 168, 2020)

PHARMACEUTICAL RESEARCH

IF4.3

2021-02-17

OAAI

Fang, Rui; Obeidat, Wasfy; Pikal, Michael J.; Bogner, Robin H.

Evaluation of Predictors of Protein Relative Stability Obtained by Solid-State Hydrogen/Deuterium Exchange Monitored by FTIR

PHARMACEUTICAL RESEARCH

IF4.3

2020-08-13

PREAI

Fang, Rui; Obeidat, Wasfy; Pikal, Michael J.; Bogner, Robin H.

Stability of Freeze-Dried Protein Formulations: Contributions of Ice Nucleation Temperature and Residence Time in the Freeze-Concentrate 冻干蛋白制剂的稳定性: 冰核温度和在冷冻浓缩物中的停留时间的贡献

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2020-06-01

PREAI

Fang, Rui; Bogner, Robin H.; Nail, Steven L.; Pikal, Michael J.

Applications of the Tunable Diode Laser Absorption Spectroscopy: In-Process Estimation of Primary Drying Heterogeneity and Product Temperature During Lyophilization 可调谐二极管激光吸收光谱的应用: 冻干过程中初级干燥异质性和产品温度的过程中估计

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2019-01-01

OAAI

Sharma, Puneet; Kessler, William J.; Bogner, Robin; Thakur, Meena; Pikal, Michael J.

Freezing of Aqueous Solutions and Chemical Stability of Amorphous Pharmaceuticals: Water Clusters Hypothesis

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2019-01-01

OAAI

Shalaev, Evgenyi; Soper, Alan; Zeitler, J. Axel; Ohtake, Satoshi; Roberts, Christopher J.; Pikal, Michael J.; Wu, Ke; Boldyreva, Elena

Impact of Natural Variations in Freeze-Drying Parameters on Product Temperature History: Application of Quasi Steady-State Heat and Mass Transfer and Simple Statistics

AAPS PHARMSCITECH

IF4

2018-09-26

OAAI

Pikal, Michael J.; Pande, Paritosh; Bogner, Robin; Sane, Pooja; Mudhivarthi, Vamsi; Sharma, Puneet

Effect of Controlled Ice Nucleation on Stability of Lactate Dehydrogenase During Freeze-Drying

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2018-03-01

PREAI

Fang, Rui; Tanaka, Kazunari; Mudhivarthi, Vamsi; Bogner, Robin H.; Pikal, Michael J.

Development of a Mini-Freeze Dryer for Material-Sparing Laboratory Processing with Representative Product Temperature History

AAPS PHARMSCITECH

IF4

2017-09-13

PREAI

Obeidat, Wasfy M.; Sahni, Ekneet; Kessler, William; Pikal, Michael

Lyophilized Drug Product Cake Appearance: What Is Acceptable?冻干药物产品蛋糕外观: 什么是可接受的？

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2017-07-01

167

PREAI

Patel, Sajal Manubhai; Nail, Steven L.; Pikal, Michael J.; Geidobler, Raimund; Winter, Gerhard; Hawe, Andrea; Davagnino, Juan; Gupta, Shailaja Rambhatla

Modeling the Secondary Drying Stage of Freeze Drying: Development and Validation of an Excel-Based Model

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2017-03-01

PREAI

Sahni, Ekneet K.; Pikal, Michael J.

AAPS PHARMSCITECH

IF4

2017-02-15

OAAI

Nail, Steven; Tchessalov, Serguei; Shalaev, Evgenyi; Ganguly, Arnab; Renzi, Ernesto; Dimarco, Frank; Wegiel, Lindsay; Ferris, Steven; Kessler, William; Pikal, Michael; Sacha, Greg; Alexeenko, Alina; Thompson, T. N.; Reiter, Cindy; Searles, James; Coiteux, Paul

Protein Internal Dynamics Associated With Pre-System Glass Transition Temperature Endothermic Events: Investigation of Insulin and Human Growth Hormone by Solid State Hydrogen/Deuterium Exchange

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2016-11-01

PREAI

Fang, Rui; Grobelny, Pawel J.; Bogner, Robin H.; Pikal, Michael J.

Freeze-Drying Process Development and Scale-Up: Scale-Up of Edge Vial Versus Center Vial Heat Transfer Coefficients, Kv

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2016-11-01

PREAI

Pikal, Michael J.; Bogner, Robin; Mudhivarthi, Vamsi; Sharma, Puneet; Sane, Pooja

Influence of Miscibility of Protein-Sugar Lyophilizates on Their Storage Stability

AAPS JOURNAL

IF3.7

2016-06-14

OAAI

Mensink, Maarten A.; Nethercott, Matthew J.; Hinrichs, Wouter L. J.; Maarschalk, Kees van der Voort; Frijlink, Henderik W.; Munson, Eric J.; Pikal, Michael J.

Spatial Variation of Pressure in the Lyophilization Product Chamber Part 1: Computational Modeling 冻干产品室中压力的空间变化第1部分: 计算模型

AAPS PHARMSCITECH

IF4

2016-05-05

PREAI

Ganguly, Arnab; Varma, Nikhil; Sane, Pooja; Bogner, Robin; Pikal, Michael; Alexeenko, Alina

Spatial Variation of Pressure in the Lyophilization Product Chamber Part 2: Experimental Measurements and Implications for Scale-up and Batch Uniformity

AAPS PHARMSCITECH

IF4

2016-03-17

PREAI

Sane, Pooja; Varma, Nikhil; Ganguly, Arnab; Pikal, Michael; Alexeenko, Alina; Bogner, Robin H.