Steven W. Muchmore - Publications, H-index & Citations

Steven W. Muchmore

sunovion pharmaceuticals inc.

29H指数

87论文数

5.8K被引数

收录论文 19

发表时间

POSIT: Flexible Shape-Guided Docking For Pose Prediction

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2015-07-24

120

OAAI

Kelley, Brian P.; Brown, Scott P.; Warren, Gregory L.; Muchmore, Steven W.

Frozen out: molecular modeling in the age of cryocrystallography

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2011-12-24

PREAI

Martin, Yvonne C.; Muchmore, Steven W.

A Unified, Probabilistic Framework for Structure- and Ligand-Based Virtual Screening

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2011-02-10

PREAI

Swann, Steven L.; Brown, Scott P.; Muchmore, Steven W.; Patel, Hetal; Merta, Philip; Locklear, John; Hajduk, Philip J.

Molecular Shape and Medicinal Chemistry: A Perspective

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2010-05-27

281

OAAI

Nicholls, Anthony; McGaughey, Georgia B.; Sheridan, Robert P.; Good, Andrew C.; Warren, Gregory; Mathieu, Magali; Muchmore, Steven W.; Brown, Scott P.; Grant, J. Andrew; Haigh, James A.; Nevins, Neysa; Jain, Ajay N.; Kelley, Brian

Cheminformatic Tools for Medicinal Chemists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2010-03-24

PREAI

Muchmore, Steven W.; Edmunds, Jeremy J.; Stewart, Kent D.; Hajduk, Philip J.

Large-Scale Application of High-Throughput Molecular Mechanics with Poisson-Boltzmann Surface Area for Routine Physics-Based Scoring of Protein-Ligand Complexes (vol 52, pg 3159, 2009)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2009-06-05

PREAI

Brown, Scott P.; Muchmore, Steven W.

Large-Scale Application of High-Throughput Molecular Mechanics with Poisson-Boltzmann Surface Area for Routine Physics-Based Scoring of Protein-Ligand Complexes

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2009-04-22

PREAI

Brown, Scott P.; Muchmore, Steven W.

Healthy skepticism: assessing realistic model performance 健康的怀疑论: 评估现实的模型性能

DRUG DISCOVERY TODAY

IF7.5

2009-04-01

100

PREAI

Brown, Scott P.; Muchmore, Steven W.; Hajduk, Philip J.

Synthesis and Evaluation of Benzothiazole-Based Analogues as Novel, Potent, and Selective Fatty Acid Amide Hydrolase Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2008-12-10

175

PREAI

Wang, Xueqing; Sarris, Katerina; Kage, Karen; Zhang, Di; Brown, Scott P.; Kolasa, Teodozyi; Surowy, Carol; El Kouhen, Odile F.; Muchmore, Steven W.; Brioni, Jorge D.; Stewart, Andrew O.

Application of belief theory to similarity data fusion for use in analog searching and lead hopping

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2008-04-17

143

PREAI

Muchmore, Steven W.; Debe, Derek A.; Metz, James T.; Brown, Scott P.; Martin, Yvonne C.; Hajduk, Philip J.

Rapid estimation of relative protein-ligand binding affinities using a high-throughput version of MM-PBSA

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2007-05-23

PREAI

Brown, Scott P.; Muchmore, Steven W.

4-amino-5-aryl-6-arylethynylpyrimidines: Structure-activity relationships of non-nucleoside adenosine kinase inhibitors 4-氨基-5-芳基-6-芳基乙炔基嘧啶: 非核苷腺苷激酶抑制剂的构效关系

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2007-02-01

PREAI

Matulenko, Mark A.; Paight, Ernest S.; Frey, Robin R.; Gomtsyan, Arthur; DiDomenico, Stanley, Jr.; Jiang, Meiqun; Lee, Chih-Hung; Stewart, Andrew O.; Yu, Haixia; Kohlhaas, Kathy L.; Alexander, Karen M.; McGaraughty, Steve; Mikusa, Joseph; Marsh, Kennan C.; Muchmore, Steven W.; Jakob, Clarissa L.; Kowaluk, Elizabeth A.; Jarvis, Michael F.; Bhagwat, Shripad S.

Crystal structures of human adenosine kinase inhibitor complexes reveal two distinct binding modes

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2006-10-14

PREAI

Muchmore, Steven W.; Smith, Richard A.; Stewart, Andrew O.; Cowart, Marlon D.; Gomtsyan, Arthur; Matulenko, Mark A.; Yu, Haixia; Severin, Jean M.; Bhagwat, Shripad S.; Lee, Chih-Hung; Kowaluk, Elizabeth A.; Jarvis, Michael F.; Jakob, Clarissa L.

High-throughput calculation of protein-ligand binding affinities: Modification and adaptation of the MM-PBSA protocol to enterprise grid computing

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2006-02-02

PREAI

Brown, Scott P.; Muchmore, Steven W.

The use of three-dimensional shape and electrostatic similarity searching in the identification of a melanin-concentrating hormone receptor 1 antagonist

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2006-01-31

OAAI

Muchmore, SW; Souers, AJ; Akritopoulou-Zanze, I

NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2004-08-28

PREAI

Huth, JR; Yu, LP; Collins, I; Mack, J; Mendoza, R; Isaac, B; Braddock, DT; Muchmore, SW; Comess, KM; Fesik, SW; Clore, GM; Levens, D; Hajduk, PJ

The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain -: RU-486 induces a transconformation that leads to active antagonism

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2003-06-01

337

OAAI

Kauppi, B; Jakob, C; Färnegårdh, M; Yang, J; Ahola, H; Alarcon, M; Calles, K; Engström, O; Harlan, J; Muchmore, S; Ramqvist, AK; Thorell, S; Öhman, L; Greer, J; Gustafsson, JÅ; Carlstedt-Duke, J; Carlquist, M

COBALT-MEDIATED CYCLOPENTENONE ANNULATION - AN APPROACH TO THE SYNTHESIS OF CYCLOCOLORENONE

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2002-05-01

PREAI

SAHA, M; MUCHMORE, S; VANDERHELM, D; NICHOLAS, KM

Role of Bcl-2 family members in apoptotic cell death

KIDNEY INTERNATIONAL

IF12.6

1999-10-01

OAAI

Thompson, CB; Vander Heiden, M; Chang, BS; Minn, AJ; Sattler, M; Liang, H; Muchmore, SW; Fesik, SW

研究方向