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收藏Ribosomal transcription is regulated by PGC-1alpha and disturbed in Huntington's disease
Jesse, Sarah; Bayer, Hanna; Alupei, Marius C.; Zuegel, Martina; Mulaw, Medhanie; Tuorto, Francesca; Malmsheimer, Silke; Singh, Karmveer; Steinacker, Juergen; Schumann, Uwe; Ludolph, Albert C.; Scharffetter-Kochanek, Karin; Witting, Anke; Weydt, Patrick; Iben, Sebastian 分享 收藏 分享 收藏 ALS-causing mutations differentially affect PGC-1α expression and function in the brain vs. peripheral tissuesBayer, Hanna; Lang, Kerstin; Buck, Eva; Higelin, Julia; Barteczko, Lara; Pasquarelli, Noemi; Sprissler, Jasmin; Lucas, Tanja; Holzmann, Karlheinz; Demestre, Maria; Lindenberg, Katrin S.; Danzer, Karin M.; Boeckers, Tobias; Ludolph, Albert C.; Dupuis, Luc; Weydt, Patrick; Witting, Anke 分享 收藏 INTEGRATED MITOCHONDRIAL FUNCTION IN HUMAN FINE-NEEDLE MUSCLE BIOPSIES OF HUNTINGTON'S DISEASE MUTATION CARRIERS AND IN TISSUES OF HDHQ111 MICEBuck, Eva; Merz, Tamara; Gumpp, Anja; Witting, Anke; Steinacker, Juergen; Zuegel, Martina; Schumann, Uwe; Landwehrmeyer, Bernhard; Weydt, Patrick; Calzia, Enrico; Lindenberg, Katrin S. 分享 收藏 RIBOSOMAL TRANSCRIPTION IS REGULATED BY PGC-1ALPHA AND DISTURBED IN HUNTINGTON'S DISEASEWeydt, Patrick; Jesse, Sarah; Bayer, Hanna; Alpei, Marius; Zuegel, Martina; Mulaw, Medhanie; Malmsheimer, Silke; Singh, Karmveer; Steinacker, Juergen; Schumann, Uwe; Ludolph, Albert; Scharffetter-Kochanek, Karin; Witting, Anke; Iben, Sebastian 分享 收藏 Alterations in the hypothalamic melanocortin pathway in amyotrophic lateral sclerosisVercruysse, Pauline; Sinniger, Jerome; El Oussini, Hajer; Scekic-Zahirovic, Jelena; Dieterle, Stephane; Dengler, Reinhard; Meyer, Thomas; Zierz, Stephan; Kassubek, Jan; Fischer, Wilhelm; Dreyhaupt, Jens; Grehl, Torsten; Hermann, Andreas; Grosskreutz, Julian; Witting, Anke; Van den Bosch, Ludo; Spreux-Varoquaux, Odile; Ludolph, Albert C.; Dupuis, Luc 分享 收藏 Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron lossScekic-Zahirovic, Jelena; Sendscheid, Oliver; El Oussini, Hajer; Jambeau, Melanie; Sun, Ying; Mersmann, Sina; Wagner, Marina; Dieterle, Stephane; Sinniger, Jerome; Dirrig-Grosch, Sylvie; Drenner, Kevin; Birling, Marie-Christine; Qiu, Jinsong; Zhou, Yu; Li, Hairi; Fu, Xiang-Dong; Rouaux, Caroline; Shelkovnikova, Tatyana; Witting, Anke; Ludolph, Albert C.; Kiefer, Friedemann; Storkebaum, Erik; lagier-Tourenne, Clotilde; Dupuis, Luc 分享 收藏 Peripheral monocytes are functionally altered and invade the CNS in ALS patientsALS患者外周单核细胞功能改变并侵入中枢神经系统Zondler, Lisa; Mueller, Kathrin; Khalaji, Samira; Bliederhaeuser, Corinna; Ruf, Wolfgang P.; Grozdanov, Veselin; Thiemann, Meinolf; Fundel-Clemes, Katrin; Freischmidt, Axel; Holzmann, Karlheinz; Strobel, Benjamin; Weydt, Patrick; Witting, Anke; Thal, Dietmar R.; Helferich, Anika M.; Hengerer, Bastian; Gottschalk, Kay-Eberhard; Hill, Oliver; Kluge, Michael; Ludolph, Albert C.; Danzer, Karin M.; Weishaupt, Jochen H. 分享 收藏 Serotonin 2B receptor slows disease progression and prevents degeneration of spinal cord mononuclear phagocytes in amyotrophic lateral sclerosisEl Oussini, Hajer; Bayer, Hanna; Scekic-Zahirovic, Jelena; Vercruysse, Pauline; Sinniger, Jerome; Dirrig-Grosch, Sylvie; Dieterle, Stephane; Echaniz-Laguna, Andoni; Larmet, Yves; Mueller, Kathrin; Weishaupt, Jochen H.; Thal, Dietmar R.; van Rheenen, Wouter; van Eijk, Kristel; Lawson, Roland; Monassier, Laurent; Maroteaux, Luc; Roumier, Anne; Wong, Philip C.; van den Berg, Leonard H.; Ludolph, Albert C.; Veldink, Jan H.; Witting, Anke; Dupuis, Luc 分享 收藏 Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytesBliederhaeuser, Corinna; Grozdanov, Veselin; Speidel, Anna; Zondler, Lisa; Ruf, Wolfgang P.; Bayer, Hanna; Kiechle, Martin; Feiler, Marisa S.; Freischmidt, Axel; Brenner, David; Witting, Anke; Hengerer, Bastian; Faendrich, Marcus; Ludolph, Albert C.; Weishaupt, Jochen H.; Gillardon, Frank; Danzer, Karin M. 分享 收藏 Mutual Exacerbation of Peroxisome Proliferator-Activated Receptor γ Coactivator 1α Deregulation and α-Synuclein OligomerizationEschbach, Judith; von Einem, Bjoern; Mueller, Kathrin; Bayer, Hanna; Scheffold, Annika; Morrison, Bradley E.; Rudolph, K. Lenhard; Thal, Dietmar R.; Witting, Anke; Weydt, Patrick; Otto, Markus; Fauler, Michael; Liss, Birgit; McLean, Pamela J.; La Spada, Albert R.; Ludolph, Albert C.; Weishaupt, Jochen H.; Danzer, Karin M. 分享 收藏 PGC-1 is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosisEschbach, Judith; Schwalenstocker, Birgit; Soyal, Selma M.; Bayer, Hanna; Wiesner, Diana; Akimoto, Chizuru; Nilsson, Ann-Charloth; Birve, Anna; Meyer, Thomas; Dupuis, Luc; Danzer, Karin M.; Andersen, Peter M.; Witting, Anke; Ludolph, Albert C.; Patsch, Wolfgang; Weydt, Patrick 分享 收藏 分享 收藏 A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onsetSoyal, Selma M.; Felder, Thomas K.; Auer, Simon; Hahne, Penelope; Oberkofler, Hannes; Witting, Anke; Paulmichl, Markus; Landwehrmeyer, G. Bernhard; Weydt, Patrick; Patsch, Wolfgang 分享 收藏 分享 收藏 分享 收藏 The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cellsEljaschewitsch, E; Witting, A; Mawrin, C; Lee, T; Schmidt, PM; Wolf, S; Hoertnagl, H; Raine, CS; Schneider-Stock, R; Nitsch, R; Ullrich, O 分享 收藏 分享 收藏 分享 收藏 
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