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Somatic mtDNA mutation burden shapes metabolic plasticity in leukemogenesis 体细胞线粒体DNA突变负担塑造了白血病发生过程中的代谢可塑性 Li-Harms, Xiujie; Sheth, Aditya; Pareek, Gautam; Kaminski, Marcin M.; Ross, Hailey S.; Wright, Christopher W.; Smith, Amber L.; Wu, Huiyun; Valentine, Marc; Schuetz, John D.; Ni, Min 分享 收藏
The role of ATP-binding Cassette subfamily B member 6 in the inner ear ATP-binding Cassette亚家族B成员6在内耳中的作用 Baril, Stefanie A.; Wilson, Katie A.; Shaik, Md Munan; Umans, Robyn A.; Lynch, John; Gose, Tomoka; Oldham, Michael L.; Wang, Yao; Fang, Jie; Zuo, Jian; Kalathur, Ravi C.; Ford, Robert C.; Coffin, Allison; Taylor, Michael R.; O'Mara, Megan L.; Schuetz, John D. 分享 收藏
The net electrostatic potential and hydration of ABCG2 affect substrate transport Gose, Tomoka; Aitken, Heather M.; Wang, Yao; Lynch, John; Rampersaud, Evadnie; Fukuda, Yu; Wills, Medb; Baril, Stefanie A.; Ford, Robert C.; Shelat, Anang; O'Mara, Megan L.; Schuetz, John D. 分享 收藏
Sonic Hedgehog activates prostaglandin signaling to stabilize primary cilium length Ansari, Shariq S.; Dillard, Miriam E.; Zhang, Yan; Austria, Mary Ashley; Boatwright, Naoko; Shelton, Elaine L.; Stewart, Daniel P.; Johnson, Amanda; Wang, Christina E.; Young, Brandon M.; Rankovic, Zoran; Hansen, Baranda S.; Pruett-Miller, Shondra M.; Carisey, Alexandre F.; Schuetz, John D.; Robinson, Camenzind G.; Ogden, Stacey K. 分享 收藏
The Imipridone ONC213 Targets α-Ketoglutarate Dehydrogenase to Induce Mitochondrial Stress and Suppress Oxidative Phosphorylation in Acute Myeloid Leukemia Su, Yongwei; Carter, Jenna L.; Li, Xinyu; Fukuda, Yu; Gray, Ashley; Lynch, John; Edwards, Holly; Ma, Jun; Schreiner, Patrick; Polin, Lisa; Kushner, Juiwanna; Dzinic, Sijana H.; Buck, Steven A.; Pruett-Miller, Shondra M.; Hege-Hurrish, Katie; Robinson, Camenzind; Qiao, Xinan; Liu, Shuang; Wu, Shuangshuang; Wang, Guan; Li, Jing; Allen, Joshua E.; Prabhu, Varun V.; Schimmer, Aaron D.; Joshi, Dhananjay; Kalhor-Monfared, Shiva; Watson, Iain D. G.; Marcellus, Richard; Isaac, Methvin B.; Al-awar, Rima; Taub, Jeffrey W.; Lin, Hai; Schuetz, John D.; Ge, Yubin 分享 收藏
The net electrostatic potential and hydration of ABCG2 affect substrate transport Gose, Tomoka; Aitken, Heather M.; Wang, Yao; Lynch, John; Rampersaud, Evadnie; Fukuda, Yu; Wills, Medb; Baril, Stefanie A.; Ford, Robert C.; Shelat, Anang; Mara, Megan L. O'; Schuetz, John D. 分享 收藏
A PPIX-binding probe facilitates discovery of PPIX-induced cell death modulation by peroxiredoxin Lynch, John; Wang, Yao; Li, Yuxin; Kavdia, Kanisha; Fukuda, Yu; Ranjit, Sabina; Robinson, Camenzind G.; Grace, Christy R.; Xia, Youlin; Peng, Junmin; Schuetz, John D. 分享 收藏
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Detection of gut and mucosal peptides through TOMAHAQ in healthy individuals Parsons, E. S.; Liu, F.; Kaushik, A.; Lee, A.; Schuetz, J.; Dunham, D.; Seastedt, H.; Ogulur, I.; Heider, A.; Tan, G.; Shah, A.; Cao, S.; Smith, E.; Kost, L.; Acharya, S.; Prunicki, M.; Rothenberg, M.; Sindher, S.; Leib, R.; Akdis, C. A.; Nadeau, K.; Lejeune, S. 分享 收藏
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The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma Pan, Min; Wright, William C.; Chapple, Richard H.; Zubair, Asif; Sandhu, Manbir; Batchelder, Jake E.; Huddle, Brandt C.; Low, Jonathan; Blankenship, Kaley B.; Wang, Yingzhe; Gordon, Brittney; Archer, Payton; Brady, Samuel W.; Natarajan, Sivaraman; Posgai, Matthew J.; Schuetz, John; Miller, Darcie; Kalathur, Ravi; Chen, Siquan; Connelly, Jon Patrick; Babu, M. Madan; Dyer, Michael A.; Pruett-Miller, Shondra M.; Freeman, Burgess B., III; Chen, Taosheng; Godley, Lucy A.; Blanchard, Scott C.; Stewart, Elizabeth; Easton, John; Geeleher, Paul 分享 收藏
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Influence of ABC transporters on the excretion of ciprofloxacin assessed with PET imaging in mice 用PET成像评估ABC转运蛋白对小鼠环丙沙星排泄的影响 Hernandez-Lozano, Irene; Wanek, Thomas; Sauberer, Michael; Filip, Thomas; Mairinger, Severin; Stanek, Johann; Traxl, Alexander; Karch, Rudolf; Schuetz, John D.; Langer, Oliver 分享 收藏
The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics 血红素调节抑制途径调节预后不良的B系急性白血病对BH3-Mimetics的易感性 Smith, Kaitlyn H.; Budhraja, Amit; Lynch, John; Roberts, Kathryn; Panetta, John C.; Connelly, Jon P.; Turnis, Meghan E.; Pruett-Miller, Shondra M.; Schuetz, John D.; Mullighan, Charles G.; Opferman, Joseph T. 分享 收藏
Lack of Multidrug Resistance-associated Protein 4 Prolongs Partial Hepatectomy-induced Hepatic Steatosis Donepudi, Ajay C.; Smith, Gregory J.; Aladelokun, Oladimeji; Lee, Yoojin; Toro, Steven J.; Pfohl, Marisa; Slitt, Angela L.; Wang, Li; Lee, Ji-Young; Schuetz, John D.; Manautou, Jose E. 分享 收藏
An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling Wijaya, Juwina; Vo, BaoHan T.; Liu, Jingjing; Xu, Beisi; Wu, Gang; Wang, Yao; Peng, Junmin; Zhang, Jin; Janke, Laura J.; Orr, Brent A.; Yu, Jiyang; Roussel, Martine F.; Schuetz, John D. 分享 收藏
Influence of Multidrug Resistance-Associated Proteins on the Excretion of the ABCC1 Imaging Probe 6-Bromo-7-[11C]Methylpurine in Mice 多药耐药相关蛋白对小鼠ABCC1成像探针6-溴-7-[11C] 甲基嘌呤排泄的影响 Zoufal, Viktoria; Mairinger, Severin; Krohn, Markus; Wanek, Thomas; Filip, Thomas; Sauberer, Michael; Stanek, Johann; Traxl, Alexander; Schuetz, John D.; Kuntner, Claudia; Pahnke, Jens; Langer, Oliver 分享 收藏
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A novel role for OATP2A1/SLCO2A1 in a murine model of colon cancer Nakanishi, Takeo; Ohno, Yasuhiro; Aotani, Rika; Maruyama, Shio; Shimada, Hiroaki; Kamo, Shunsuke; Oshima, Hiroko; Oshima, Masanobu; Schuetz, John D.; Tamai, Ikumi 分享 收藏