Karin Briner - Publications, H-index & Citations

Karin Briner

Eli Lilly

20H指数

86论文数

1.3K被引数

收录论文 16

发表时间

Diversity-oriented synthesis encoded by deoxyoligonucleotides (vol 14, 4930, 2023)

NATURE COMMUNICATIONS

IF15.7

2023-11-21

OAAI

Hudson, Liam; Mason, Jeremy W.; Westphal, Matthias V.; Richter, Matthieu J. R.; Thielman, Jonathan R.; Hua, Bruce K.; Gerry, Christopher J.; Xia, Guoqin; Osswald, Heather L.; Knapp, John M.; Tan, Zher Yin; Kokkonda, Praveen; Tresco, Ben I. C.; Liu, Shuang; Reidenbach, Andrew G.; Lim, Katherine S.; Poirier, Jennifer; Capece, John; Bonazzi, Simone; Gampe, Christian M.; Smith, Nichola J.; Bradner, James E.; Coley, Connor W.; Clemons, Paul A.; Melillo, Bruno; Hon, C. Suk-Yee; Ottl, Johannes; Dumelin, Christoph E.; Schaefer, Jonas V.; Faust, Ann Marie E.; Berst, Frederic; Schreiber, Stuart L.; Zecri, Frederic J.; Briner, Karin

DNA-encoded library-enabled discovery of proximity-inducing small molecules

NATURE CHEMICAL BIOLOGY

IF13.7

2023-11-02

OAAI

Mason, Jeremy W.; Chow, Yuen Ting; Hudson, Liam; Tutter, Antonin; Michaud, Gregory; Westphal, Matthias V.; Shu, Wei; Ma, Xiaolei; Tan, Zher Yin; Coley, Connor W.; Clemons, Paul A.; Bonazzi, Simone; Berst, Frederic; Briner, Karin; Liu, Shuang; Zecri, Frederic J.; Schreiber, Stuart L.

Rational Screening for Cooperativity in Small-Molecule Inducers of Protein-Protein Associations

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-10-10

OAAI

Liu, Shuang; Tong, Bingqi; Mason, Jeremy W.; Ostrem, Jonathan M.; Tutter, Antonin; Hua, Bruce K.; Tang, Sunny A.; Bonazzi, Simone; Briner, Karin; Berst, Frederic; Zecri, Frederic J.; Schreiber, Stuart L.

Diversity-oriented synthesis encoded by deoxyoligonucleotides

NATURE COMMUNICATIONS

IF15.7

2023-08-15

OAAI

Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy 用于癌症免疫治疗的选择性IKZF2胶降解剂的发现和表征

CELL CHEMICAL BIOLOGY

IF7.2

2023-03-01

OAAI

Bonazzi, Simone; d'Hennezel, Eva; Beckwith, Rohan E. J.; Xu, Lei; Fazal, Aleem; Magracheva, Anna; Ramesh, Radha; Cernijenko, Artiom; Antonakos, Brandon; Bhang, Hyo-eun C.; Caro, Roxana Garcia; Cobb, Jennifer S.; Ornelas, Elizabeth; Ma, Xiaolei; Wartchow, Charles A.; Clifton, Matthew C.; Forseth, Ry R.; Fortnam, Bethany Hughes; Lu, Hongbo; Csibi, Alfredo; Tullai, Jennifer; Carbonneau, Seth; Thomsen, Noel M.; Larrow, Jay; Chie-Leon, Barbara; Hainzl, Dominik; Gu, Yi; Lu, Darlene; Meyer, Matthew J.; Alexander, Dylan; Kinyamu-Akunda, Jacqueline; Sabatos-Peyton, Catherine A.; Dales, Natalie A.; Zecri, Frederic J.; Jain, Rishi K.; Shulok, Janine; Wang, Y. Karen; Briner, Karin; Porter, Jeffery A.; Tallarico, John A.; Engelman, Jeffrey A.; Dranoff, Glenn; Bradner, James E.; Visser, Michael; Solomon, Jonathan M.

Use of Intramolecular 1,5-Sulfur-Oxygen and 1,5-Sulfur-Halogen Interactions in the Design of N-Methyl-5-aryl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 Splicing Modulators

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-04-06

PREAI

Axford, Jake; Sung, Moo Je; Manchester, John; Chin, Donovan; Jain, Monish; Shin, Youngah; Dix, Ina; Hamann, Lawrence G.; Cheung, Atwood K.; Sivasankaran, Rajeev; Briner, Karin; Dales, Natalie A.; Hurley, Brian

Systematic Chemogenetic Library Assembly

CELL CHEMICAL BIOLOGY

IF7.2

2020-09-01

OAAI

Canham, Stephen M.; Wang, Yuan; Cornett, Allen; Auld, Douglas S.; Baeschlin, Daniel K.; Patoor, Maude; Skaanderup, Philip R.; Honda, Ayako; Llamas, Luis; Wendel, Greg; Mapa, Felipa A.; Aspesi, Peter, Jr.; Labbe-Giguere, Nancy; Gamber, Gabriel G.; Palacios, Daniel S.; Schuffenhauer, Ansgar; Deng, Zhan; Nigsch, Florian; Frederiksen, Mathias; Bushell, Simon M.; Rothman, Deborah; Jain, Rishi K.; Hemmerle, Horst; Briner, Karin; Porter, Jeffery A.; Tallarico, John A.; Jenkins, Jeremy L.

New Horizons in Drug Discovery - Understanding and Advancing Kinase Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-07-15

OAAI

Laufer, Stefan; Briner, Karin; Bajorath, Juergen; Georg, Gunda I.; Wang, Shaomeng

Water-Compatible Cycloadditions of Oligonucleotide-Conjugated Strained Allenes for DNA-Encoded Library Synthesis

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-04-08

OAAI

Westphal, Matthias, V; Hudson, Liam; Mason, Jeremy W.; Pradeilles, Johan A.; Zecri, Frederic J.; Briner, Karin; Schreiber, Stuart L.

The Discovery of LML134, a Histamine H3 Receptor Inverse Agonist for the Clinical Treatment of Excessive Sleep Disorders 组胺H3受体反向激动剂LML134用于临床治疗过度睡眠障碍的发现

CHEMMEDCHEM

IF3.4

2019-05-21

PREAI

Troxler, Thomas; Feuerbach, Dominik; Zhang, Xuechun; Yang, Charles R.; Lagu, Bharat; Perrone, Mark; Wang, Tie-Lin; Briner, Karin; Bock, Mark G.; Auberson, Yves P.

Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2018-11-08

108

OAAI

Cheung, Atwood K.; Hurley, Brian; Kerrigan, Ryan; Shu, Lei; Chin, Donovan N.; Shen, Yiping; O'Brien, Gary; Sung, Moo Je; Hou, Ying; Axford, Jake; Cody, Emma; Sun, Robert; Fazal, Aleem; Fridrich, Cary; Sanchez, Carina C.; Tomlinson, Ronald C.; Jain, Monish; Deng, Lin; Hoffmaster, Keith; Song, Cheng; Van Hoosear, Mailin; Shin, Youngah; Servais, Rebecca; Towler, Christopher; Hild, Marc; Curtis, Daniel; Dietrich, William F.; Hamann, Lawrence G.; Briner, Karin; Chen, Karen S.; Kobayashi, Dione; Sivasankaran, Rajeev; Dales, Natalie A.

Behavioral effects of a novel Benzofuranyl-Piperazine serotonin-2c receptor agonist suggest a Potential Therapeutic application in the Treatment of Obsessive-Compulsive Disorder

FRONTIERS IN PSYCHIATRY

IF3.2

2017-05-22

OAAI

Rodriguez, Michelle M.; Overshiner, Carl; Leander, J. David; Li, Xia; Morrow, Denise; Conway, Richard G.; Nelson, David L.; Briner, Karin; Witkin, Jeffrey M.

From Ergolines to Indoles: Improved Inhibitors of the Human H3 Receptor for the Treatment of Narcolepsy 从麦角林到吲哚: 用于治疗发作性睡病的人类H3受体的改良抑制剂

CHEMMEDCHEM

IF3.4

2014-11-12

PREAI

Auberson, Yves P.; Troxler, Thomas; Zhang, Xuechun; Yang, Charles R.; Feuerbach, Dominik; Liu, Yu-Chih; Lagu, Bharat; Perrone, Mark; Lei, Lijun; Shen, Xiaoxia; Zhang, Dushan; Wang, Chunxiu; Wang, Tie-Lin; Briner, Karin; Bock, Mark G.

Synthesis and structure-activity relationships of novel arylpiperazines as potent and selective agonists of the melanocortin subtype-4 receptor

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2004-01-06

PREAI

Richardson, TI; Ornstein, PL; Briner, K; Fisher, MJ; Backer, RT; Biggers, CK; Clay, MP; Emmerson, PJ; Hertel, LW; Hsiung, HM; Husain, S; Kahl, SD; Lee, JA; Lindstrom, TD; Martinelli, MJ; Mayer, JP; Mullaney, JT; O'Brien, TP; Pawlak, JM; Revell, KD; Shah, J; Zgombick, JM; Herr, RJ; Melekhov, A; Sampson, PB; King, CHR

Iodoacetoxylation of glycals using cerium(IV) ammonium nitrate, sodium iodide, and acetic acid:: Stereoselective synthesis of 2-deoxy-2-iodo-α-mannopyranosyl acetates

ORGANIC LETTERS

IF5

1999-08-21

PREAI

Roush, WR; Narayan, S; Bennett, CE; Briner, K

Studies on the synthesis of aureolic acid antibiotics: Acyloin glycosidation studies

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

1996-09-06

PREAI

Roush, WR; Briner, K; Kesler, BS; Murphy, M; Gustin, DJ

研究方向