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Y

Yinyan Sun

national institute of biological sciences
H指数:21
被引数:3,571

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Strategy and efficiency-redefined discovery of novel nanomolar tyrosinase inhibitors: AI de novo molecular generation + expert-guided structural optimization

策略与效率：重新定义新型纳摩尔酪氨酸酶抑制剂的发现——AI从头分子生成+专家引导的结构优化

Journal of Advanced Research
IF13
2025-12-280
OAAI
Yinyan Sun; Jiahui Wang; Wenchao Chen; Hao Wen; Meiling Feng; Xiaotian Niu; Jia Zhi; Shengjie Hu; Shan Wang; Hong Cai; Bin Ju; Keda Yang; Xiaoying Jiang; Renren Bai
Discovery of Novel Dihydroxyphenol Tyrosinase Inhibitors for Treatment of Pigmentation: From Enzyme Screening to Three-Dimensional Human Skin Melanin Evaluation

新型二羟基苯酚酪氨酸酶抑制剂的发现及其在色素沉着治疗中的应用：从酶筛选到三维人体皮肤黑色素评估

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2025-11-010
PRE
Wang, Jiahui; Sun, Yinyan; Jiang, Xiaoying; Wen, Hao; Cai, Hong; Feng, Meiling; Niu, Xiaotian; Wang, Shan; Zhi, Jia; Xie, Junchao; Wang, Rui; Chen, Wenchao; Bai, Renren
An IgM-like inhalable ACE2 fusion protein broadly neutralizes SARS-CoV-2 variants
NATURE COMMUNICATIONS
IF15.7
2023-08-258
OAAI
Liu, Juan; Mao, Fengfeng; Chen, Jianhe; Lu, Shuaiyao; Qi, Yonghe; Sun, Yinyan; Fang, Linqiang; Yeung, Man Lung; Liu, Chunmei; Yu, Guimei; Li, Guangyu; Liu, Ximing; Yao, Yuansheng; Huang, Panpan; Hao, Dongxia; Liu, Zibing; Ding, Yu; Liu, Haimo; Yang, Fang; Chen, Pan; Sa, Rigai; Sheng, Yao; Tian, Xinxin; Peng, Ran; Li, Xue; Luo, Junmian; Cheng, Yurui; Zheng, Yule; Lin, Yongqing; Song, Rui; Jin, Ronghua; Huang, Baoying; Choe, Hyeryun; Farzan, Michael; Yuen, Kwok-Yung; Tan, Wenjie; Peng, Xiaozhong; Sui, Jianhua; Li, Wenhui
Receptor Usage of a Novel Bat Lineage C Betacoronavirus Reveals Evolution of Middle East Respiratory Syndrome-Related Coronavirus Spike Proteins for Human Dipeptidyl Peptidase 4 Binding
JOURNAL OF INFECTIOUS DISEASES
IF4.5
2018-01-1672
OAAI
Lau, Susanna K. P.; Zhang, Libiao; Luk, Hayes K. H.; Xiong, Lifeng; Peng, Xingwen; Li, Kenneth S. M.; He, Xiangyang; Zhao, Pyrear Su-Hui; Fan, Rachel Y. Y.; Wong, Antonio C. P.; Ahmed, Syed Shakeel; Cai, Jian-Piao; Chan, Jasper F. W.; Sun, Yinyan; Jin, Dongyan; Chen, Honglin; Lau, Terrence C. K.; Kok, Raven K. H.; Li, Wenhui; Yuen, Kwok-Yung; Woo, Patrick C. Y.

研究方向

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李
李文辉
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Y
Yonghe Qi
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J
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W
Wenhui He
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Z
Zhiyi Jing
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张雨霞 封面图
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H
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张
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F
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R
Renren Bai
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