James L. Manley - Publications, H-index & Citations

James L. Manley

columbia university

122H指数

459论文数

4.9W被引数

收录论文 38

发表时间

Multiple human enhancer RNAs contain long translated open reading frames

GENES & DEVELOPMENT

IF7.7

2025-12-01

PREAI

Vlasov, Pavel A.; Ogami, Koichi; Valenzuela, Elizabeth; Kawaguchi, Risa Karakida; Jovanovic, Marko; Manley, James L.

SUGP1 loss drives SF3B1 hotspot mutant missplicing in cancer SUGP1缺失驱动SF3B1热点突变体在癌症中的错剪接

Cell Reports

IF6.9

2025-07-25

OAAI

Peiqi Xing; Pedro Bak-Gordon; Jindou Xie; Jian Zhang; Zhaoqi Liu; James L. Manley

Cancer-associated SF3B1 mutation K700E causes widespread changes in U2/branchpoint recognition without altering splicing 癌症相关SF3B1突变K700E在不改变剪接的情况下导致U2/分支位点识别发生广泛变化

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2025-03-26

OAAI

Damianov, Andrey; Lin, Chia-; Zhang, Jian; Manley, James L.; Black, Douglas L.

SF3B1: from core splicing factor to oncogenic driver SF3B1：从核心剪接因子到致癌驱动因子

RNA

IF5

2025-01-07

OAAI

Bak-Gordon, Pedro; Manley, James L.

Splicing dysregulation in glioblastoma alters the function of cell migration-related genes

GLIA

IF5.1

2024-10-24

OAAI

Seong, Minu; Bak-Gordon, Pedro; Liu, Zhaoqi; Canoll, Peter D.; Manley, James L.

The E592K variant of SF3B1 creates unique RNA missplicing and associates with high-risk MDS without ring sideroblasts

BLOOD ADVANCES

IF7.1

2024-07-26

OAAI

Choi, In Young; Ling, Jonathan P.; Zhang, Jian; Helmenstine, Eric; Walter, Wencke; Tsakiroglou, Panagiotis; Bergman, Riley E.; Philippe, Celine; Manley, James L.; Rouault-Pierre, Kevin; Li, Bing; Wiseman, Daniel H.; Batta, Kiran; Ouseph, Madhu; Bernard, Elsa; Dubner, Benjamin; Li, Xiao; Haferlach, Torsten; Koget, Anna; Fazal, Salman; Jain, Tania; Gocke, Christopher D.; DeZern, Amy E.; Dalton, William Brian

Even-skipped represses transcription by binding TATA binding protein and blocking the TFIID-TATA box interaction

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

OAAI

Li, C; Manley, JL

DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2022-12-02

OAAI

Zhang, Jian; Huang, Ji; Xu, Ke; Xing, Peiqi; Huang, Yue; Liu, Zhaoqi; Tong, Liang; Manley, James L.

SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-12-20

OAAI

Lieu, Yen K.; Liu, Zhaoqi; Ali, Abdullah M.; Wei, Xin; Penson, Alex; Zhang, Jian; An, Xiuli; Rabadan, Raul; Raza, Azra; Manley, James L.; Mukherjee, Siddhartha

Widespread intron retention impairs protein homeostasis in C9orf72 ALS brains

GENOME RESEARCH

IF5.5

2020-10-14

OAAI

Wang, Qingqing; Conlon, Erin G.; Manley, James L.; Rio, Donald C.

SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation

AUTOPHAGY

IF14.3

2020-08-07

OAAI

Richard, Patricia; Feng, Shuang; Tsai, Yueh-Lin; Li, Wencheng; Rinchetti, Paola; Muhith, Ubayed; Irizarry-Cole, Juan; Stolz, Katharine; Sanz, Lionel A.; Hartono, Stella; Hoque, Mainul; Tadesse, Saba; Seitz, Herve; Lotti, Francesco; Hirano, Michio; Chedin, Frederic; Tian, Bin; Manley, James L.

Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation

NATURE COMMUNICATIONS

IF15.7

2020-06-23

OAAI

Cheng, Larry C.; Zheng, Dinghai; Baljinnyam, Erdene; Sun, Fangzheng; Ogami, Koichi; Yeung, Percy Luk; Hoque, Mainul; Lu, Chi-Wei; Manley, James L.; Tian, Bin

Pan-cancer analysis identifies mutations in SUGP1 that recapitulate mutant SF3B1 splicing dysregulation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-04-24

OAAI

Liu, Zhaoqi; Zhang, Jian; Sun, Yiwei; Perea-Chamblee, Tomin E.; Manley, James L.; Rabadan, Raul

TCF3 mutually exclusive alternative splicing is controlled by long-range cooperative actions between hnRNPH1 and PTBP1

RNA

IF5

2019-08-07

OAAI

Yamazaki, Takashi; Liu, Lizhi; Manley, James L.

C9orf72 and triplet repeat disorder RNAs: G-quadruplex formation, binding to PRC2 and implications for disease mechanisms

RNA

IF5

2019-05-02

OAAI

Wang, Xueyin; Goodrich, Karen J.; Conlon, Erin G.; Gao, Jianchao; Erbse, Annette H.; Manley, James L.; Cech, Thomas R.

Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine

CELL DEATH AND DIFFERENTIATION

IF15.4

2018-10-15

OAAI

Carbone, Michele; Amelio, Ivano; Affar, El Bachir; Brugarolas, James; Cannon-Albright, Lisa A.; Cantley, Lewis C.; Cavenee, Webster K.; Chen, Zhijian; Croce, Carlo M.; D'Andrea, Alan; Gandara, David; Giorgi, Carlotta; Jia, Wei; Lan, Qing; Mak, Tak Wah; Manley, James L.; Mikoshiba, Katsuhiko; Onuchic, Jose N.; Pass, Harvey I.; Pinton, Paolo; Prives, Carol; Rothman, Nathaniel; Sebti, Said M.; Turkson, James; Wu, Xifeng; Yang, Haining; Yu, Herbert; Melino, Gerry

NRDE-2, the human homolog of fission yeast Nrl1, prevents DNA damage accumulation in human cells

RNA BIOLOGY

IF3.4

2018-08-02

OAAI

Richard, Patricia; Ogami, Koichi; Chen, Yaqiong; Feng, Shuang; Moresco, James J.; Yates, John R., III; Manley, James L.

ELIFE

IF0

2018-07-13

OAAI

Conlon, Erin G.; Fagegaltier, Delphine; Agius, Phaedra; Davis-Porada, Julia; Gregory, James; Hubbard, Isabel; Kang, Kristy; Kim, Duyang; Phatnani, Hemali; Shneider, Neil A.; Manley, James L.

Molecular basis for the recognition of the human AAUAAA polyadenylation signal 识别人AAUAAA多聚腺苷酸化信号的分子基础

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-12-05

OAAI

Sun, Yadong; Zhang, Yixiao; Hamilton, Keith; Manley, James L.; Shi, Yongsheng; Walz, Thomas; Tong, Liang

Comparative analysis of alternative polyadenylation in S. cerevisiae and S. pombe

GENOME RESEARCH

IF5.5

2017-09-15

OAAI

Liu, Xiaochuan; Hoque, Mainul; Larochelle, Marc; Lemay, Jean-Francois; Yurko, Nathan; Manley, James L.; Bachand, Francois; Tian, Bin

研究方向