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Travis Stams

novartis biomedical research
H指数:26
被引数:3,622

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Author Correction: Targeting the SHOC2–RAS interaction in RAS-mutant cancers

作者更正: 靶向RAS突变癌症中的SHOC2-RAS相互作用

Nature
IF48.5
2025-07-010
OA
Zachary J. Hauseman; Frédéric Stauffer; Kim S. Beyer; Sandra Mollé; Elena Cavicchioli; Jean-Remy Marchand; Michelle Fodor; Jessica Viscomi; Anxhela Dhembi; Stéphanie Katz; Beatrice Faggion; Mylene Lanter; Grainne Kerr; Daniela Schildknecht; Cornelia Handl; Danilo Maddalo; Carole Pissot Soldermann; Jacob Brady; Om Shrestha; Zachary Nguyen; Lukas Leder; Gregor Cremosnik; Sandra Lopez Romero; Ulrich Hassiepen; Travis Stams; Markus Linder; Giorgio G. Galli; Daniel A. Guthy; Daniel A. King; Sauveur-Michel Maira; Claudio R. Thoma; Veronika Ehmke; Luca Tordella
Targeting the SHOC2-RAS interaction in RAS-mutant cancers

靶向RAS突变癌症中的SHOC2-RAS相互作用

NATURE
IF48.5
2025-05-071
OA
Hauseman, Zachary J.; Stauffer, Frederic; Beyer, Kim S.; Molle, Sandra; Cavicchioli, Elena; Marchand, Jean-Remy; Fodor, Michelle; Viscomi, Jessica; Dhembi, Anxhela; Katz, Stephanie; Faggion, Beatrice; Lanter, Mylene; Kerr, Grainne; Schildknecht, Daniela; Handl, Cornelia; Maddalo, Danilo; Soldermann, Carole Pissot; Brady, Jacob; Shrestha, Om; Nguyen, Zachary; Leder, Lukas; Cremosnik, Gregor; Romero, Sandra Lopez; Hassiepen, Ulrich; Stams, Travis; Linder, Markus; Galli, Giorgio G.; Guthy, Daniel A.; King, Daniel A.; Maira, Sauveur-Michel; Thoma, Claudio R.; Ehmke, Veronika
Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2020-09-10131
PREAI
LaMarche, Matthew J.; Acker, Michael; Argintaru, Andreea; Bauer, Daniel; Boisclair, Julie; Chan, Homan; Chen, Christine Hiu-Tung; Chen, Ying-Nan; Chen, Zhouliang; Deng, Zhan; Dore, Michael; Dunstan, David; Fan, Jianmei; Fekkes, Peter; Firestone, Brant; Fodor, Michelle; Garcia-Fortanet, Jorge; Fortin, Pascal D.; Fridrich, Cary; Giraldes, John; Glick, Meir; Grunenfelder, Denise; Hao, Huia-Xiang; Hentemann, Martin; Ho, Samuel; Jouk, Andriana; Kang, Zhao B.; Karki, Rajesh; Kato, Mitsunori; Keen, Nick; Koenig, Robert; LaBonte, Laura R.; Larrow, Jay; Liu, Gang; Liu, Shumei; Majumdar, Dyuti; Mathieu, Simon; Meyer, Matthew J.; Mohseni, Morvarid; Ntaganda, Rukundo; Palermo, Mark; Perez, Lawrence; Pu, Minying; Ramsey, Timothy; Reilly, John; Sarver, Patrick; Sellers, William R.; Sendzik, Martin; Shultz, Michael D.; Slisz, Joanna; Slocum, Kelly; Smith, Troy; Spence, Stanley; Stams, Travis; Straub, Christopher; Tamez, Victoriano, Jr.; Toure, Bakary-Barry; Towler, Christopher; Wang, Ping; Wang, Hongyun; Williams, Sarah L.; Yang, Fan; Yu, Bing; Zhang, Ji-Hu; Zhu, Suzanne
Allosteric SHP2 phosphatase inhibition: Multiple mechanisms and chemotypes
CANCER RESEARCH
IF16.6
2019-07-010
PRE
LaMarche, Matthew J.; Bagdanoff, Jeff; Acker, Mike; Chen, Ying-Nan; Chan, Homan; Dore, Michael; Firestone, Brant; Fodor, Michelle; Garcia-Fortanet, Jorge; Hentemann, Murphy; Kato, Mitsunori; Koenig, Robert; La Bonte, Laura; Liu, Shumei; Mohseni, Movarid; Ntaganda, Rukundo; Sarver, Patrick; Smith, Troy; Sendzik, Martin; Stams, Travis; Spence, Stan; Towler, Chris; Wang, Hongyun; Wang, Ping; Williams, Sarah; Chen, Zhouliang; Hao, Huaixiang; Liu, Gang; Liu, Chen; McNeill, Eric; Yu, Bing
Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors (vol 62, pg 1781, 2019)
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-03-221
OAAI
Bagdanoff, Jeffrey T.; Chen, Zhouliang; Acker, Michael; Chen, Ying-Nan; Chan, Homan; Dore, Michael; Firestone, Brant; Fodor, Michelle; Fortanet, Jorge; Hentemann, Murphy; Kato, Mitsunori; Koenig, Robert; LaBonte, Laura R.; Liu, Shumei; Mohseni, Movarid; Ntaganda, Rukundo; Sarver, Patrick; Shultz, Michael D.; Smith, Troy; Sendzik, Martin; Stams, Travis; Spence, Stan; Towler, Christopher; Wang, Hongyun; Wang, Ping; Williams, Sarah L.; LaMarche, Matthew J.
6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors (vol 62, pg 1793, 2019)
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-03-221
OAAI
Sarver, Patrick; Acker, Michael; Bagdanoff, Jeffrey T.; Chen, Zhouliang; Chen, Ying-Nan; Chan, Homan; Firestone, Brant; Fodor, Michelle; Fortanet, Jorge; Hao, Huaixiang; Hentemann, Murphy; Jouk, Andriana; Kato, Mitsunori; Koenig, Robert; LaBonte, Laura R.; Liu, Gang; Liu, Shumei; Liu, Chen; McNeill, Eric; Mohseni, Morvarid; Shultz, Michael D.; Sendzik, Martin; Stams, Travis; Spence, Stan; Tamez, Victoriano; Tichkule, Ritesh; Towler, Christopher; Wang, Hongyun; Wang, Ping; Williams, Sarah L.; Yu, Bing; LaMarche, Matthew J.
Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-01-2872
OAAI
Bagdanoff, Jeffrey T.; Chen, Zhouliang; Acker, Michael; Chen, Ying-Nan; Chan, Homan; Dore, Michael; Firestone, Brant; Fodor, Michelle; Fortanet, Jorge; Hentemann, Murphy; Kato, Mitsunori; Koenig, Robert; LaBonte, Laura R.; Liu, Shumei; Mohseni, Movarid; Ntaganda, Rukundo; Sarver, Patrick; Smith, Troy; Sendzik, Martin; Stams, Travis; Spence, Stan; Towler, Christopher; Wang, Hongyun; Wang, Ping; Williams, Sarah L.; LaMarche, Matthew J.
6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-01-2875
OAAI
Sarver, Patrick; Acker, Michael; Bagdanoff, Jeffrey T.; Chen, Zhouliang; Chen, Ying-Nan; Chan, Homan; Firestone, Brant; Fodor, Michelle; Fortanet, Jorge; Hao, Huaixiang; Hentemann, Murphy; Kato, Mitsunori; Koenig, Robert; LaBonte, Laura R.; Liu, Gang; Liu, Shumei; Liu, Chen; McNeill, Eric; Mohseni, Morvarid; Sendzik, Martin; Stams, Travis; Spence, Stan; Tamez, Victoriano; Tichkule, Ritesh; Towler, Christopher; Wang, Hongyun; Wang, Ping; Williams, Sarah L.; Yu, Bing; LaMarche, Matthew J.
Simultaneous inhibition of SHP2 phosphatase at two allosteric sites
CANCER RESEARCH
IF16.6
2018-07-011
PRE
Fodor, Michelle; Price, Edmund; Wang, Ping; Lu, Hengyu; Argintaru, Andreea; Chen, Zhouliang; Glick, Meir; Hao, Huai-Xiang; Kato, Mitsunori; Koenig, Robert; LaRochelle, Jonathan R.; Liu, Gang; McNeill, Eric; Majumdar, Dyuti; Nishiguchi, Gisele; Perez, Lawrence; Paris, Greg; Quinn, Christopher; Ramsey, Timothy; Sendzik, Martin; Shultz, Michael; Williams, Sarah; Stams, Travis; Blacklow, Stephen C.; LaMarche, Matthew J.; Acker, Michael G.
Dual Allosteric Inhibition of SHP2 Phosphatase
ACS CHEMICAL BIOLOGY
IF3.8
2018-01-05110
OAAI
Fodor, Michelle; Price, Edmund; Wang, Ping; Lu, Hengyu; Argintaru, Andreea; Chen, Zhouliang; Glick, Meir; Hao, Huai-Xiang; Kato, Mitsunori; Koenig, Robert; LaRochelle, Jonathan R.; Liu, Gang; McNeill, Eric; Majumdar, Dyuti; Nishiguchi, Gisele A.; Perez, Lawrence B.; Paris, Gregory; Quinn, Christopher M.; Ramsey, Timothy; Sendzik, Martin; Shultz, Michael David; Williams, Sarah L.; Stams, Travis; Blacklow, Stephen C.; Acker, Michael G.; LaMarche, Matthew J.
Conformational activation and allosteric inhibition of SHP2 in RTK-driven cancers
CANCER RESEARCH
IF16.6
2017-07-010
PRE
Acker, Michael G.; Chen, Ying-Nan P.; LaMarche, Matthew J.; Chan, Ho Man; Fekkes, Peter; Garcia-Fortanet, Jorge; LaRochelle, Jonathan R.; Antonakos, Brandon; Chen, Christine Hiu-Tung; Chen, Zhuoliang; Cooke, Vesselina G.; Dobson, Jason R.; Deng, Zhan; Feng, Fei; Firestone, Brant; Fodor, Michelle; Fridrich, Cary; Gao, Hui; Hao, Huai-Xiang; Jacob, Jaison; Ho, Samuel; Hsiao, Kathy; Kang, Zhao B.; Karki, Rajesh; Kato, Mitsunori; Larrow, Jay; La Bonte, Laura R.; Liu, Gang; Liu, Shumei; Majumdar, Dyuti; Meyer, Matthew J.; Palermo, Mark; Pu, Minying; Price, Edmund; Shakya, Subarna; Shultz, Michael D.; Venkatesan, Kavitha; Wang, Ping; Warmuth, Markus; Williams, Sarah; Yang, Guizhi; Yuan, Jing; Zhang, Ji-Hu; Zhu, Ping; Blacklow, Stephen C.; Ramsey, Timothy; Keen, Nicholas J.; Sellers, William R.; Stams, Travis; Fortin, Pascal D.
Antibacterial and Solubility Optimization of Thiomuracin A
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2016-07-1214
PREAI
LaMarche, Matthew J.; Leeds, Jennifer A.; Brewer, Jason; Dean, Karl; Ding, Jian; Dzink-Fox, Joanne; Gamber, Gabe; Jain, Akash; Kerrigan, Ryan; Krastel, Philipp; Lee, Kwangho; Lombardo, Franco; McKenney, David; Neckermann, Georg; Osborne, Colin; Palestrant, Deborah; Patane, Michael A.; Rann, Elin M.; Robinson, Zachary; Schmitt, Esther; Stams, Travis; Tiamfook, Stacey; Yu, Donghui; Whitehead, Lewis
Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2016-07-12248
OAAI
Fortanet, Jorge Garcia; Chen, Christine Hiu-Tung; Chen, Ying-Nan P.; Chen, Zhouliang; Deng, Zhan; Firestone, Brant; Fekkes, Peter; Fodor, Michelle; Fortin, Pascal D.; Fridrich, Cary; Grunenfelder, Denise; Ho, Samuel; Kang, Zhao B.; Karki, Rajesh; Kato, Mitsunori; Keen, Nick; LaBonte, Laura R.; Larrow, Jay; Lenoir, Francois; Liu, Gang; Liu, Shumei; Lombardo, Franco; Majumdar, Dyuti; Meyer, Matthew J.; Palermo, Mark; Perez, Lawrence; Pu, Minying; Ramsey, Timothy; Sellers, William R.; Shultz, Michael D.; Stams, Travis; Towler, Christopher; Wang, Ping; Williams, Sarah L.; Zhang, Ji-Hu; LaMarche, Matthew J.
Identification of NVP-TNKS656: The Use of Structure-Efficiency Relationships To Generate a Highly Potent, Selective, and Orally Active Tankyrase Inhibitor
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2013-08-13114
PRE
Shultz, Michael D.; Cheung, Atwood K.; Kirby, Christina A.; Firestone, Brant; Fan, Jianmei; Chen, Christine Hiu-Tung; Chen, Zhouliang; Chin, Donovan N.; DiPietro, Lucian; Fazal, Aleem; Feng, Yun; Fortin, Pascal D.; Gould, Ty; Lagu, Bharat; Lei, Huangshu; Lenoir, Francois; Majumdar, Dyuti; Ochala, Etienne; Palermo, M. G.; Ly Pham; Pu, Minying; Smith, Troy; Stams, Travis; Tomlinson, Ronald C.; Toure, B. Barry; Visser, Michael; Wang, Run Ming; Waters, Nigel J.; Shao, Wenlin

研究方向

暂未获取到该数据
M
Michelle Fodor
H 指数:13论文数:48被引数:2,172
M
Matthew J. LaMarche
H 指数:29论文数:156被引数:3,942
M
Michael D. Shultz
H 指数:35论文数:140被引数:7,192
M
Michael Acker
H 指数:42论文数:198被引数:6,342
M
Mitsunori Kato
H 指数:21论文数:49被引数:5,116
Z
Zhouliang Chen
H 指数:9论文数:27被引数:1,937
B
Brant Firestone
H 指数:16论文数:57被引数:2,812
S
Shumei Liu
H 指数:23论文数:81被引数:4,244
R
Robert Koenig
H 指数:5论文数:21被引数:520
M
Martin Sendzik
H 指数:15论文数:45被引数:991