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E

Eigen Peralta

fate therapeutics, inc.
H指数:10
被引数:1,606

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iPSC-derived trimodal T cells engineered with CAR, TCR, and hnCD16 modalities can overcome antigen escape in heterogeneous tumors

iPSC来源的三模态T细胞（通过CAR、TCR和hnCD16模态工程化改造）能够克服异质性肿瘤中的抗原逃逸。

Cell Reports Medicine
IF10.6
2025-06-190
OAAI
Bi-Huei Yang; Alma Gutierrez; Angela Liao; Soheila Shirinbak; Bjoern Gaertner; Mochtar Pribadi; Hui-Yi Chu; Pei-Fang Tsai; Yu-Sheng Eason Lin; David Gonzalez; Wen-I Yeh; Chia-Wei Chang; Ryan Bjordahl; Tom Lee; Martin Hosking; Eigen Peralta; Bahram Valamehr
Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacy

iPSC来源的CAR T细胞通过工程化改造克服多种实体瘤疗效障碍，实现对HER2的偏好性肿瘤靶向。

Cell Stem Cell
IF20.4
2025-06-040
PRE
Martin P. Hosking; Soheila Shirinbak; Kyla Omilusik; Shilpi Chandra; Mika K. Kaneko; Angela Gentile; Susumu Yamamoto; Bishwas Shrestha; Joy Grant; Megan Boyett; Demetrio Cardenas; Hannah Keegan; Samad Ibitokou; Carolina Pavon; Takahiro Mizoguchi; Tatsuya Ihara; Daisuke Nakayama; Ramzey Abujarour; Tom T. Lee; Raedun Clarke; Jode Goodridge; Eigen Peralta; Tatsuo Maeda; Junichi Takagi; Takao Arimori; Yukinari Kato; Bahram Valamehr
A novel CD3ε fusion receptor allows T cell engager use in TCR-less allogeneic CAR T cells to improve activity and prevent antigen escape

一种新型的CD3ε融合受体允许在无TCR的同种异体CAR T细胞中使用T细胞连接器，以提高活性并防止抗原逃逸。

Molecular Therapy
IF12
2025-05-280
PRE
Dan Lu; Hui-Yi Chu; Soo Park; Mark Landon; Masanao Tsuda; Earl Avramis; Carissa Dege; Thomas Dailey; Yijia Pan; Sandeep Kothapally Hanok; Matthew Denholtz; Ramzey Abujarour; Tom Lee; John Goulding; Martin Hosking; Jodie Goodridge; Eigen Peralta; Bahram Valamehr
OFF-THE-SHELF IPSC-DERIVED CAR-T CELLS CONTAINING SEVEN FUNCTIONAL EDITS OVERCOME ANTIGEN HETEROGENEITY, IMPROVE TRAFFICKING, AND WITHSTAND IMMUNOSUPPRESSION ASSOCIATED WITH FAILED TUMOR TREATMENT
JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2022-11-070
OA
Hosking, Martin; Shirinbak, Soheila; Shrestha, Bishwas; Grant, Joy; Omilusik, Kyla; Keegan, Hannah; Cardenas, Demetrio; Gentile, Angela; Chandra, Shilpi; Loter, Lorraine; Linderhof, Lexe; Brookhouser, Nicholas; Kennedy, Stephanie; Martinez, Francisco; Campanati, Loraine; Ecker, Chris; Yuan, Xu; Palomares, Karina; Lai, Yi-Shin; Fong, Lauren; Pan, Yijia; Sikaroodi, Shohreh; Jelcic, Mark; Chu, Philip; Mehta, Amit; Smith, Layton; Peralta, Eigen; Lee, Tom; Abujarour, Ramzey; Clarke, Raedun; Valamehr, Bob

研究方向

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B
Bahram Valamehr
H 指数:28论文数:159被引数:3,326
H
Hui-Yi Chu
H 指数:9论文数:49被引数:325
A
Aimee L. Edinger
H 指数:38论文数:89被引数:1.7万
S
Soheila Shirinbak
H 指数:9论文数:57被引数:361
T
Tom Lee
H 指数:36论文数:291被引数:5,679
A
Alec Witty
H 指数:11论文数:51被引数:2,101
Y
Yijia Pan
H 指数:13论文数:87被引数:1,026
M
Matthew Denholtz
H 指数:14论文数:48被引数:1,727
M
Mochtar Pribadi
H 指数:16论文数:73被引数:1,441
B
Bob Valamehr
H 指数:3论文数:31被引数:23