未登录 Taming hemoglobin chemistry-a new hemoglobin-based oxygen carrier engineered with both decreased rates of nitric oxide scavenging and lipid oxidation Cooper, Chris E.; Simons, Michelle; Dyson, Alex; Eriksson, Nelida Leiva; Silkstone, Gary G. A.; Syrett, Natalie; Allen-Baume, Victoria; Buelow, Leif; Ronda, Luca; Mozzarelli, Andrea; Singer, Mervyn; Reeder, Brandon J. 分享 收藏
Stability of Maleimide-PEG and Mono-Sulfone-PEG Conjugation to a Novel Engineered Cysteine in the Human Hemoglobin Alpha Subunit 马来酰亚胺-PEG和单砜-PEG与人血红蛋白 α 亚基中新的工程半胱氨酸缀合的稳定性 Cooper, Chris E.; Bird, Matthew; Sheng, XiaoBo; Choi, Ji-Won; Silkstone, Gary G. A.; Simons, Michelle; Syrett, Natalie; Piano, Riccardo; Ronda, Luca; Bettati, Stefano; Paredi, Gianluca; Mozzarelli, Andrea; Reeder, Brandon J. 分享 收藏
Engineering hemoglobin to enable homogenous PEGylation without modifying protein functionality Cooper, Chris E.; Silkstone, Gary G. A.; Simons, Michelle; Gretton, Svetlana; Rajagopal, Badri S.; Allen-Baume, Victoria; Syrett, Natalie; Shaik, Thoufieq; Popa, Gina; Sheng, XiaoBo; Bird, Matthew; Choi, Ji-Won; Piano, Riccardo; Ronda, Luca; Bettati, Stefano; Paredi, Gianluca; Mozzarelli, Andrea; Reeder, Brandon J. 分享 收藏
Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute 将酪氨酸残基工程化为血红蛋白可增强血红素的减少，减少氧化应激并增加基于血红蛋白的血液替代品的血管保留 Cooper, Chris E.; Silkstone, Gary G. A.; Simons, Michelle; Rajagopal, Badri; Syrett, Natalie; Shaik, Thoufieq; Gretton, Svetlana; Welbourn, Elizabeth; Bulow, Leif; Eriksson, Nelida Leiva; Ronda, Luca; Mozzarelli, Andrea; Eke, Andras; Mathe, Domokos; Reeder, Brandon J. 分享 收藏
Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriers Simons, Michelle; Gretton, Svetlana; Silkstone, Gary G. A.; Rajagopal, Badri S.; Allen-Baume, Victoria; Syrett, Natalie; Shaik, Thoufieq; Leiva-Eriksson, Nelida; Ronda, Luca; Mozzarelli, Andrea; Strader, Michael B.; Alayash, Abdu I.; Reeder, Brandon J.; Cooper, Chris E. 分享 收藏
Engineering tyrosine electron transfer pathways decreases oxidative toxicity in hemoglobin: implications for blood substitute design Silkstone, Gary G. A.; Silkstone, Rebecca S.; Wilson, Michael T.; Simons, Michelle; Bulow, Leif; Kallberg, Kristian; Ratanasopa, Khuanpiroon; Ronda, Luca; Mozzarelli, Andrea; Reeder, Brandon J.; Cooper, Chris E. 分享 收藏
The hydrogen-peroxide-induced radical behaviour in human cytochrome c-phospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant Rajagopal, Badri S.; Edzuma, Ann N.; Hough, Michael A.; Blundell, Katie L. I. M.; Kagan, Valerian E.; Kapralov, Alexandr A.; Fraser, Lewis A.; Butt, Julea N.; Silkstone, Gary G.; Wilson, Michael T.; Svistunenko, Dimitri A.; Worrall, Jonathan A. R. 分享 收藏
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Disruption of the M80-Fe ligation stimulates the translocation of cytochrome c to the cytoplasm and nucleus in nonapoptotic cells Godoy, Luiz C.; Munoz-Pinedo, Cristina; Castro, Laura; Cardaci, Simone; Schonhoff, Christopher M.; King, Michael; Tortora, Veronica; Marin, Monica; Miao, Qian; Jiang, Jian Fei; Kapralov, Alexandr; Jemmerson, Ronald; Silkstone, Gary G.; Patel, Jinal N.; Evans, James E.; Wilson, Michael T.; Green, Douglas R.; Kagan, Valerian E.; Radi, Rafael; Mannick, Joan B. 分享 收藏
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