未登录.png)
分享.png)
收藏Lead Generation for a HIF Prolyl Hydroxylase Inhibitor: Discovery of (7-Hydroxy-[1,2,4]triazolo[1,5-a]pyridine-8-carbonyl)glycine as a Lead Compound of EnarodustatHIF脯氨酰羟化酶抑制剂的开发：作为Enarodustat先导化合物的(7-羟基-[1,2,4]三唑并[1,5-a]吡啶-8-甲酰)甘氨酸的发现
Ogoshi, Y; Matsui, T; Mitani, I; Yokota, M; Terashita, M; Motoda, D; Ueyama, K; Hotta, T; Ito, T; Suma, A; Fukui, K; Deai, K; Yoshiuchi, H; Ito, S; Abe, H 分享 收藏 Discovery and SAR of JTE-151: A Novel RORγ Inhibitor for Clinical DevelopmentMaeba, Takaki; Hirata, Kazuyuki; Kotoku, Masayuki; Seki, Noriyoshi; Maeda, Katsuya; Hirashima, Shintaro; Yamanaka, Hiroshi; Sakai, Takayuki; Obika, Shingo; Hori, Akimi; Hara, Yoshinori; Noji, Satoru; Suwa, Yoshihiro; Yokota, Masahiro; Fujioka, Shingo; Yamaguchi, Takayuki; Katsuda, Yoshiaki; Hata, Takahiro; Miyagawa, Naoki; Arita, Kojo; Nomura, Yukihiro; Taniguchi, Toshio; Asahina, Kota; Aratsu, Yusuke; Naka, Yuichi; Adachi, Tsuyoshi; Nomura, Akihiro; Akai, Shota; Oshida, Shin-ichi; Pai, Sudhakar; Crowe, Paul; Bradley, Erin; Steensma, Ruo; Tao, Haiyan; Fenn, Morgan; Babine, Robert; Li, Xiaolin; Thacher, Scott; Soeta, Takahiro; Ukaji, Yutaka; Shiozaki, Makoto 分享 收藏 Discovery of Selective Transforming Growth Factor β Type II Receptor Inhibitors as Antifibrosis AgentsMiwa, Shohei; Yokota, Masahiro; Ueyama, Yoshifumi; Maeda, Katsuya; Ogoshi, Yosuke; Seki, Noriyoshi; Ogawa, Naoki; Nishihata, Jun; Nomura, Akihiro; Adachi, Tsuyoshi; Kitao, Yuki; Nozawa, Keisuke; Ishikawa, Tomohiro; Ukaji, Yutaka; Shiozaki, Makoto 分享 收藏 Discovery of Second Generation RORγ Inhibitors Composed of an Azole ScaffoldKotoku, Masayuki; Maeba, Takaki; Fujioka, Shingo; Yokota, Masahiro; Seki, Noriyoshi; Ito, Keisuke; Suwa, Yoshihiro; Ikenogami, Taku; Hirata, Kazuyuki; Hase, Yasunori; Katsuda, Yoshiaki; Miyagawa, Naoki; Arita, Kojo; Asahina, Kota; Noguchi, Masato; Nomura, Akihiro; Doi, Satoki; Adachi, Tsuyoshi; Crowe, Paul; Tao, Haiyan; Thacher, Scott; Hashimoto, Hiromasa; Suzuki, Takayoshi; Shiozaki, Makoto 分享 收藏 Discovery of JTZ-951: A HIF Prolyl Hydroxylase Inhibitor for the Treatment of Renal AnemiaOgoshi, Yosuke; Matsui, Takuya; Mitani, Ikuo; Yokota, Masahiro; Terashita, Masakazu; Motoda, Dai; Ueyama, Kazuhito; Hotta, Takahiro; Ito, Takashi; Hase, Yasunori; Fukui, Kenji; Deai, Katsuya; Yoshiuchi, Hiromi; Ito, Soichiro; Abe, Hiroyuki 分享 收藏 QUVE: QoE Maximizing Framework for Video-StreamingKimura, Takuto; Yokota, Masahiro; Matsumoto, Arifumi; Takeshita, Kei; Kawano, Taichi; Sato, Kazumichi; Yamamoto, Hiroshi; Hayashi, Takanori; Shiomoto, Kohei; Miyazaki, Kenichi 分享 收藏 Discovery of (1S,2R,3R)-2,3-Dimethyl-2-phenyl-1-sulfamidocyclopropanecarboxylates: Novel and Highly Selective Aggrecanase InhibitorsShiozaki, Makoto; Maeda, Katsuya; Miura, Tomoya; Kotoku, Masayuki; Yamasaki, Takayuki; Matsuda, Isamu; Aoki, Kenta; Yasue, Katsutaka; Imai, Hiroto; Ubukata, Minoru; Suma, Akira; Yokota, Masahiro; Hotta, Takahiro; Tanaka, Masahiro; Hase, Yasunori; Haas, Julia; Fryer, Andrew M.; Laird, Ellen R.; Littmann, Nicole M.; Andrews, Steven W.; Josey, John A.; Mimura, Takayuki; Shinozaki, Yuichi; Yoshiuchi, Hiromi; Inaba, Takashi 分享 收藏 The mouse APG10 homologue, an E2-like enzyme for Apg12p conjugation, facilitates MAP-LC3 modification小鼠APG10同源物是Apg12p缀合的E2-like酶，可促进MAP-LC3修饰Nemoto, T; Tanida, I; Tanida-Miyake, E; Minematsu-Ikeguchi, N; Yokota, M; Ohsumi, M; Ueno, T; Kominami, E 分享 收藏 分享 收藏 分享 收藏 分享 收藏 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
