未登录 Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4 Allen, Samantha J.; Parthasarathy, Gopal; Darke, Paul L.; Diehl, Ronald E.; Ford, Rachael E.; Hall, Dawn L.; Johnson, Scott A.; Reid, John C.; Rickert, Keith W.; Shipman, Jennifer M.; Soisson, Stephen M.; Zuck, Paul; Munshi, Sanjeev K.; Lumb, Kevin J. 分享 收藏
Structural Basis for Selective Small Molecule Kinase Inhibition of Activated c-Met Rickert, Keith W.; Patel, Sangita B.; Allison, Timothy J.; Byrne, Noel J.; Darke, Paul L.; Ford, Rachael E.; Guerin, David J.; Hall, Dawn L.; Kornienko, Maria; Lu, Jun; Munshi, Sanjeev K.; Reid, John C.; Shipman, Jennifer M.; Stanton, Elizabeth F.; Wilson, Kevin J.; Young, Jonathon R.; Soisson, Stephen M.; Lumb, Kevin J. 分享 收藏
Structural Basis for the Inhibition of RNase H Activity of HIV-1 Reverse Transcriptase by RNase H Active Site-Directed Inhibitors Su, Hua-Poo; Yan, Youwei; Prasad, G. Sridhar; Smith, Robert F.; Daniels, Christopher L.; Abeywickrema, Pravien D.; Reid, John C.; Loughran, H. Marie; Kornienko, Maria; Sharma, Sujata; Grobler, Jay A.; Xu, Bei; Sardana, Vinod; Allison, Timothy J.; Williams, Peter D.; Darke, Paul L.; Hazuda, Daria J.; Munshi, Sanjeev 分享 收藏
Structure of Human Prostasin, a Target for the Regulation of Hypertension Rickert, Keith W.; Kelley, Paul; Byrne, Noel J.; Diehl, Ronald E.; Hall, Dawn L.; Montalvo, Allison M.; Reid, John C.; Shipman, Jennifer M.; Thomas, Bradley W.; Munshi, Sanjeev K.; Darke, Paul L.; Su, Hua-Poo 分享 收藏
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PYRROLINONE-BASED HIV PROTEASE INHIBITORS - DESIGN, SYNTHESIS, AND ANTIVIRAL ACTIVITY - EVIDENCE FOR IMPROVED TRANSPORT SMITH, AB; HIRSCHMANN, R; PASTERNAK, A; GUZMAN, MC; YOKOYAMA, A; SPRENGELER, PA; DARKE, PL; EMINI, EA; SCHLEIF, WA 分享 收藏
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CYCLIC SULFOLANES AS NOVEL AND HIGH-AFFINITY P-2 LIGANDS FOR HIV-1 PROTEASE INHIBITORS GHOSH, AK; THOMPSON, WJ; LEE, HY; MCKEE, SP; MUNSON, PM; DUONG, TT; DARKE, PL; ZUGAY, JA; EMINI, EA; SCHLEIF, WA; HUFF, JR; ANDERSON, PS 分享 收藏
3-TETRAHYDROFURAN AND PYRAN URETHANES AS HIGH-AFFINITY P2-LIGANDS FOR HIV-1 PROTEASE INHIBITORS GHOSH, AK; THOMPSON, WJ; MCKEE, SP; DUONG, TT; LYLE, TA; CHEN, JC; DARKE, PL; ZUGAY, JA; EMINI, EA; SCHLEIF, WA; HUFF, JR; ANDERSON, PS 分享 收藏
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Identification of MK-944a: A second clinical candidate from the hydroxylaminepentanamide isostere series of HIV protease inhibitors Dorsey, BD; McDonough, C; McDaniel, SL; Levin, RB; Newton, CL; Hoffman, JM; Darke, PL; Zugay-Murphy, JA; Emini, EA; Schleif, WA; Olsen, DB; Stahlhut, MW; Rutkowski, CA; Kuo, LC; Lin, JH; Chen, IW; Michelson, SR; Holloway, MK; Huff, JR; Vacca, JP 分享 收藏
Nonpeptidal P-2 ligands for HIV protease inhibitors: Structure-based design, synthesis, and biological evaluation Ghosh, AK; Kincaid, JF; Walters, DE; Chen, Y; Chaudhuri, NC; Thompson, WJ; Culberson, C; Fitzgerald, PMD; Lee, HY; McKee, SP; Munson, PM; Duong, TT; Darke, PL; Zugay, JA; Schleif, WA; Axel, MG; Lin, J; Huff, JR 分享 收藏
A priori prediction of activity for HIV-1 protease inhibitors employing energy minimization in the active site (vol 38, pg 308, 1995) Holloway, MK; Wai, JM; Halgren, TA; Fitzgerald, PMD; Vacca, JP; Dorsey, BD; Levin, RB; Thompson, WJ; Chen, LJ; deSolms, SJ; Gaffin, N; Ghosh, AK; Giuliani, EA; Graham, SL; Guare, JP; Hungate, RW; Lyle, TA; Sanders, WM; Tucker, TJ; Wiggins, M; Wiscount, CM; Woltersdorf, OW; Young, SD; Darke, PL; Zugay, JA 分享 收藏
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