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Arun K. Ghosh

Purdue University

77H指数
812论文数
2.4W被引数
收录论文 247
发表时间
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Design; synthesis; and X-ray structural studies of potent SARS-CoV-2 Mpro inhibitors containing tetrahydroisoquinoline-3-carboxamides as P2 ligands设计、合成及X射线结构研究含有四氢异喹啉-3-甲酰胺作为P2配体的强效SARS-CoV-2 Mpro抑制剂
errRSC Medicinal Chemistry
IF3.6
err2026-07-24
err0
errOAAI
errArun K. Ghosh Corresponding Author; Ashish Sharma; Satyanarayana Iddum; Sydney N. Bogan; Uttara Jayashankar; Emma K. Lendy; Shin-ichiro Hattori; Nobuyo Higashi-Kuwata; Hiroaki Mitsuya; Andrew D. Mesecar
err分享
err收藏
Asymmetric Synthesis of (-)-Catunaregin, an Angiogenesis Inhibitor from Mangroves红树来源的血管生成抑制剂(-)-Catunaregin的不对称合成
errJournal of Organic Chemistry
IF3.6
err2026-04-01
err0
PREAI
errGhosh, Arun K.; Vultorius, Christopher
err分享
err收藏
High-Throughput Cardiac Hypertrophy Phenotyping Supports Lead Optimization of GRK5 Inhibitors高通量心脏肥厚表型分析支持GRK5抑制剂的先导化合物优化
errACS Medicinal Chemistry Letters
IF4
err2025-12-15
err0
errOAAI
errPia Steinkuhl; Anca Kliesow Remes; Carmen Carrillo García; Amol Sonawane; Ranjith Kumar Gadi; Arun K. Ghosh; John J. G. Tesmer; Oliver J. Müller; Dennis Schade
err分享
err收藏
A curated global dataset of social contact between diverse language communities一个精选的全球性社会接触数据集，涉及不同语言社群之间的互动
errScientific Data
IF6.9
err2025-12-11
err0
errOAAI
errEri Kashima; Francesca Di Garbo; Oona Raatikainen; Robert Forkel; Rosnátaly Avelino; Sacha Beck; Anna Berge; Ana Blanco Pena; Ross Bowden; Nicolás Brid; Joseph M. Brincat; María Belén Carpio; Alexander Cobbinah; Paola Cúneo; Deginet Wotango Doyiso; Anne-Maria Fehn; Saloumeh Gholami; Arun Ghosh; Hannah Gibson; Elizabeth Hall; Katja Hannß; Hannah Haynie; Jerry J. Jacka; Mathias Jenny; Richard Kowalik; Sonal Kulkarni-Joshi; Maarten Mous; Marcela Mendoza; Cristina Messineo; Francesca Romana Moro; Hank Nater; Michelle Ocasio; Bruno Olsson; Ana María Ospina Bozzi; Agustina Paredes; Admire Phiri; Nicolas Quint; Erika Sandman; Dineke Schokkin; Ruth Singer; Ellen Smith-Dennis; Lameen Souag; Yunus Sulistyono; Yvonne Treis; Matthias Urban; Jill Vaughan; Georg Ziegelmeyer; Veronika Zikmundová; Ricardo Napoleão de Souza; Kaius Sinnemäki
err分享
err收藏
Potent and Selective G Protein-coupled Receptor Kinase 5 Inhibitors: Design, Synthesis, Evaluation, and X-ray Structural Studies强效且选择性的G蛋白偶联受体激酶5抑制剂：设计、合成、评价和X射线结构研究
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-11-26
err0
PREAI
errArun K. Ghosh; Rajesh Manda; Ranjith Kumar Gadi; Yueyi Chen; Natalie M. Galvan; John J.G. Tesmer
err分享
err收藏
Diastereoselective intramolecular oxidopyrylium–alkene [5 + 2]-cycloaddition of substrates with a β-chiral center on alkene tethers: synthesis of 8-oxabicyclo-[3.2.1]-octenone heterocycles外消旋选择性分子内氧化吡喃鎓–烯烃[5 + 2]-环加成反应：以烯烃连接臂上具有β-手性中心的底物合成8-氧杂双环[3.2.1]辛烯酮杂环化合物
errOrg. Biomol. Chem.
IF2.7
err2025-11-18
err0
errOAAI
errArun K. Ghosh; Denver Hopkins
err分享
err收藏
TiCl 4 -Promoted Intramolecular Friedel-Crafts Cyclization of α-Keto-phenylbutanoates: Synthesis of Substituted Indane and Indene DerivativesTiCl4促进的α-酮基苯丁酸酯分子内傅-克环化反应：取代二氢萘和茚衍生物的合成
errSYNLETT
IF1.4
err2025-10-01
err0
PREAI
errGhosh, Arun K.; McDonald, Tristan John
err分享
err收藏
Design, synthesis, evaluation and X-ray structural studies of potent HIV-1 protease inhibitors containing substituted oxaspirocyclic carbamates as the P2 ligands设计、合成、评价及X射线结构研究含取代氧螺环氨基甲酸酯作为P2配体的强效HIV-1蛋白酶抑制剂
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-06-20
err0
PREAI
errArun K. Ghosh; Ryan Shaktah; Ajay K. Ghosh; Megan E. Johnson; Dipendra Bhandari; Masayuki Amano; Manabu Aoki; Andrey Kovalevsky; Hiroaki Mitsuya
err分享
err收藏
Potent, Selective, and Drug-like G Protein-coupled Receptor Kinase 5 and 6 Inhibitors: Design, Synthesis, and X-ray Structural Studies强效、选择性且具有药物样特性的G蛋白偶联受体激酶5和6抑制剂：设计、合成与X射线结构研究
errChemMedChem
IF3.4
err2025-05-19
err0
PREAI
errArun K Ghosh; Ranjith Kumar Gadi; Yueyi Chen; Sandali Piladuwa Gamage; Kathryn McCauley; John J. G. Tesmer
err分享
err收藏
G Protein-Coupled Receptor Kinase Isoforms Differentially Regulate Dopamine Receptor SubtypesG蛋白偶联受体激酶异构体差异调控多巴胺受体亚型
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errMoritz, Amy; Madaras, Nora s.; Snyder, Kirsten k.; Boldizsar, Noelia m.; Haider, Raphael; Drube, Julia; Ghosh, Arun k.; Tesmer, John; Hoffmann, Carsten; Sibley, David r.
err分享
err收藏
SF3B1 thermostability as an assay for splicing inhibitor interactions
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2025-02-01
err0
errOAAI
errAmorello, Angela N.; Reddy, Guddeti Chandrashekar; Melillo, Bruno; Cravatt, Benjamin F.; Ghosh, Arun K.; Jurica, Melissa S.
err分享
err收藏
Design, synthesis, and X-ray structural studies of a series of highly potent selective, and drug-like G protein-coupled receptor kinase 5 inhibitors
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-01-01
err0
PREAI
errGhosh, Arun K.; Chen, Yueyi; Gadi, Ranjith Kumar; Sonawane, Amol; Gamage, Sandali Piladuwa; Tesmer, John J. G.
err分享
err收藏
Total Syntheses of Strasseriolide A and Strasseriolide B, Potent Antimalarial Agents
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2024-08-09
err0
PREAI
errGhosh, Arun K.; Gulliver, John P.
err分享
err收藏
Structural insights and rational design, optimization of highly potent and selective novel GRK5/6 inhibitors for cancer therapy
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errChen, Yueyi; Sonawane, Amol D.; Manda, Rajesh; Gadi, Ranjith K.; Ghosh, Arun K.; Tesmer, John J.
err分享
err收藏
Exploration of P1 and P4 modifications of nirmatrelvir: Design, synthesis, biological evaluation, and X-ray structural studies of SARS-CoV-2 Mpro inhibitors
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-03-01
err4
PREAI
errGhosh, Arun K.; Yadav, Monika; Iddum, Satyanarayana; Ghazi, Somayeh; Lendy, Emma K.; Jayashankar, Uttara; Beechboard, Sydney N.; Takamatsu, Yuki; Hattori, Shin-ichiro; Aamano, Masayuki; Higashi-Kuwata, Nobuyo; Mitsuya, Hiroaki; Mesecar, Andrew D.
err分享
err收藏
Development of a new class of potent and highly selective G protein-coupled receptor kinase 5 inhibitors and structural insight from crystal structures of inhibitor complexes
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-01-01
err3
PREAI
errChen, Yueyi; Sonawane, Amol; Manda, Rajesh; Gadi, Ranjith Kumar; Tesmer, John J. G.; Ghosh, Arun K.
err分享
err收藏
GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants
errSCIENCE ADVANCES
IF12.5
err2023-07-14
err2
errOAAI
errAoki, Manabu; Aoki-Ogata, Hiromi; Bulut, Haydar; Hayashi, Hironori; Takamune, Nobutoki; Kishimoto, Naoki; Tanaka, Hiroki; Higashi-Kuwata, Nobuyo; Hattori, Shin-ichiro; Das, Debananda; Rao, Kalapala Venkateswara; Iwama, Kazuya; Davis, David A.; Hasegawa, Kazuya; Murayama, Kazutaka; Yarchoan, Robert; Ghosh, Arun K.; Pau, Alice K.; Machida, Shinichi; Misumi, Shogo; Mitsuya, Hiroaki
err分享
err收藏
Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological evaluation
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-07-01
err2
errOAAI
errGhosh, Arun K.; Mishevich, Jennifer L.; Kovela, Satish; Shaktah, Ryan; Ghosh, Ajay K.; Johnson, Megan; Wang, Yuan-Fang; Wong-Sam, Andres; Agniswamy, Johnson; Amano, Masayuki; Takamatsu, Yuki; Hattori, Shin-ichiro; Weber, Irene T.; Mitsuya, Hiroaki
err分享
err收藏
Total Synthesis of Neuroprotective Agents, (+)-Lycibarbarine A and (-)-Lycibarbarine B
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2023-06-02
err2
errOAAI
errGhosh, Arun K.; Harper, Marc; Robinson, William L.
err分享
err收藏
Delineation of the G Protein-Coupled Receptor Kinase Phosphorylation Sites Within the D1 Dopamine Receptor and Their Role in Regulating Receptor Function
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2023-06-01
err0
errOAAI
errMadaras, Nora S.; Rankin, Michele L.; Free, R. Benjamin; Haider, Raphael; Drube, Julia; Ghosh, Arun K.; Tesmer, John J. G.; Hoffmann, Carsten; Sibley, David R.; Moritz, Amy E.
err分享
err收藏

研究方向

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