未登录 Ortho group activation of a bromopyrrole ester in Suzuki-Miyaura cross-coupling reactions: Application to the synthesis of new microtubule depolymerizing agents with potent cytotoxic activities Gupton, John T.; Yeudall, Scott; Telang, Nakul; Hoerrner, Megan; Huff, Ellis; Crawford, Evan; Lounsbury, Katie; Kimmel, Michael; Curry, William; Harrison, Andrew; Juekun, Wen; Shimozono, Alex; Ortolani, Joe; Lescalleet, Kristin; Patteson, Jon; Moore-Stoll, Veronica; Rohena, Cristina C.; Mooberry, Susan L.; Obaidullah, Ahmad J.; Kellogg, Glen E.; Sikorski, James A. 分享 收藏
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Carboxylated, heteroaryl-substituted chalcones as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases Meng, Charles Q.; Ni, Liming; Worsencroft, Kimberly J.; Ye, Zhihong; Weingarten, M. David; Simpson, Jacob E.; Skudlarek, Jason W.; Marino, Elaine M.; Suen, Ki-Ling; Kunsch, Charles; Souder, Amy; Howard, Randy B.; Sundell, Cynthia L.; Wasserman, Martin A.; Sikorski, James A. 分享 收藏
AGIX-4207 [2-[4-[[1-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic acid], a novel antioxidant and anti-inflammatory compound: Cellular and biochemical characterization of antioxidant activity and inhibition of redox-sensitive inflammatory gene expression Kunsch, C; Luchoomun, J; Chen, XL; Dodd, GL; Karu, KS; Meng, CQ; Marino, EM; Olliff, LK; Piper, JD; Qiu, FH; Sikorski, JA; Somers, PK; Suen, KL; Thomas, S; Whalen, AM; Wasserman, MA; Sundell, CL 分享 收藏
Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases Meng, CQ; Somers, PK; Hoong, LK; Zheng, XS; Ye, ZH; Worsencroft, KJ; Simpson, JE; Hotema, MR; Weingarten, MD; MacDonald, ML; Hill, RR; Marino, EM; Suen, KL; Luchoomun, J; Kunsch, C; Landers, LK; Stefanopoulos, D; Howard, RB; Sundell, CL; Saxena, U; Wasserman, MA; Sikorski, JA 分享 收藏
Discovery of a simple picomolar inhibitor of cholesteryl ester transfer protein Reinhard, EJ; Wang, JL; Durley, RC; Fobian, YM; Grapperhaus, ML; Hickory, BS; Massa, MA; Norton, MB; Promo, MA; Tollefson, MB; Vernier, WF; Connolly, DT; Witherbee, BJ; Melton, MA; Regina, KJ; Smith, ME; Sikorski, JA 分享 收藏
Chiral N,N-disubstituted trifluoro-3-amino-2-propanols are potent inhibitors of cholesteryl ester transfer protein Durley, RC; Grapperhaus, ML; Hickory, BS; Massa, MA; Wang, JL; Spangler, DP; Mischke, DA; Parnas, BL; Fobian, YM; Rath, NP; Honda, DD; Zeng, M; Connolly, DT; Heuvelman, DM; Witherbee, BJ; Melton, MA; Glenn, KC; Krul, ES; Smith, ME; Sikorski, JA 分享 收藏
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Discovery of chiral N,N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein Durley, RC; Grapperhaus, ML; Massa, MA; Mischke, DA; Parnas, BL; Fobian, YM; Rath, NP; Honda, DD; Zeng, M; Connolly, DT; Heuvelman, DM; Witherbee, BJ; Glenn, KC; Krul, ES; Smith, ME; Sikorski, JA 分享 收藏
Selective peptidic and peptidomimetic inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase: A new approach to antifungal therapy 白色念珠菌肉豆蔻酰coa的选择性肽和拟肽抑制剂: 蛋白质N-肉豆蔻酰转移酶: 抗真菌治疗的新方法 Sikorski, JA; Devadas, B; Zupec, ME; Freeman, SK; Brown, DL; Lu, HF; Nagarajan, S; Mehta, PP; Wade, AC; Kishore, NS; Bryant, ML; Getman, DP; McWherter, CA; Gordon, JI 分享 收藏
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Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity Devadas, B; Freeman, SK; Zupec, ME; Lu, HF; Nagarajan, SR; Kishore, NS; Lodge, JK; Kuneman, DW; McWherter, CA; Vinjamoori, DV; Getman, DP; Gordon, JI; Sikorski, JA 分享 收藏
Conformationally constrained [p-(omega-aminoalkyl)phenacetyl]-L-seryl-L-lysyl dipeptide amides as potent peptidomimetic inhibitors of Candida albicans and human myristoyl-CoA:protein N-myristoyl transferase Nagarajan, SR; Devadas, B; Zupec, ME; Freeman, SK; Brown, DL; Lu, HF; Mehta, PP; Kishore, NS; McWherter, CA; Getman, DP; Gordon, JI; Sikorski, JA 分享 收藏
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