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K
Kenneth A. Johnson
University of Texas at Austin
70
H指数
305
论文数
1.7W
被引数
0
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85
发表时间
发表时间
IF
被引数
Slow PPi release enhances fidelity of the SARS-CoV-2 RNA dependent RNA polymerase
缓慢PPi释放增强了SARS-CoV-2 RNA依赖性RNA聚合酶的保真度
Journal of Biological Chemistry
IF
3.9
2026-04-17
0
OA
AI
Tyler L. Dangerfield; Ingrid Marko; Kenneth A. Johnson
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Enzyme Kinetic Analysis for the 21st Century
21世纪酶动力学分析
Biochemistry
IF
3
2026-03-06
0
PRE
AI
Ingrid Marko; Kenneth A. Johnson
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Mechanistic conformational and substrate selectivity profiles emerging in the evolution of enzymes via parallel trajectories
NATURE COMMUNICATIONS
IF
15.7
2024-08-16
2
OA
AI
Karamitros, Christos S.; Murray, Kyle; Kumada, Yoichi; Johnson, Kenneth A.; D'Arcy, Sheena; Georgiou, George
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Unraveling the mechanisms of PAMless DNA interrogation by SpRY-Cas9
NATURE COMMUNICATIONS
IF
15.7
2024-04-30
7
OA
AI
Hibshman, Grace N.; Bravo, Jack P. K.; Hooper, Matthew M.; Dangerfield, Tyler L.; Zhang, Hongshan; Finkelstein, Ilya J.; Johnson, Kenneth A.; Taylor, David W.
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Dynamics of Exonuclease Proofreading by T7 DNA Polymerase During DNA Replication
JOURNAL OF BIOLOGICAL CHEMISTRY
IF
3.9
2024-03-01
0
OA
AI
Dangerfield, Tyler; Johnson, Kenneth
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High fidelity DNA strand-separation is the major specificity determinant in DNA methyltransferase CcrM's catalytic mechanism
NUCLEIC ACIDS RESEARCH
IF
13.1
2023-06-16
1
OA
AI
Konttinen, Olivia; Carmody, Jason; Kurnik, Martin; Johnson, Kenneth A.; Reich, Norbert
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Kinetics of DNA strand transfer between polymerase and proofreading exonuclease active sites regulates error correction during high-fidelity replication
JOURNAL OF BIOLOGICAL CHEMISTRY
IF
3.9
2023-01-01
8
OA
AI
Dangerfield, Tyler L.; Johnson, Kenneth A.
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Kinetics of elementary steps in loop-mediated isothermal amplification (LAMP) show that strand invasion during initiation is rate-limiting
NUCLEIC ACIDS RESEARCH
IF
13.1
2022-12-30
17
OA
AI
Dangerfield, Tyler L.; Paik, Inyup; Bhadra, Sanchita; Johnson, Kenneth A.; Ellington, Andrew D.
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Substrate Specificity and Kinetics of RNA Hydrolysis by SARS-CoV-2 NSP10/14 Exonuclease
ACS BIO & MED CHEM AU
IF
4.3
2022-11-16
3
OA
AI
Dangerfield, TylerL.; Johnson, Kenneth A.
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Leveraging intrinsic flexibility to engineer enhanced enzyme catalytic activity
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF
9.1
2022-06-03
25
OA
AI
Karamitros, Christos S.; Murray, Kyle; Winemiller, Brent; Lamb, Candice; Stone, Everett M.; D'Arcy, Sheena; Johnson, Kenneth A.; Georgiou, George
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Substrate specificity and proposed structure of the proofreading complex of T7 DNA polymerase
JOURNAL OF BIOLOGICAL CHEMISTRY
IF
3.9
2022-03-01
10
OA
AI
Dangerfield, Tyler L.; Kirmizialtin, Serdal; Johnson, Kenneth A.
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Conformational dynamics during misincorporation and mismatch extension defined using a DNA polymerase with a fluorescent artificial amino acid
JOURNAL OF BIOLOGICAL CHEMISTRY
IF
3.9
2022-01-01
5
OA
AI
Dangerfield, Tyler L.; Kirmizialtin, Serdal; Johnson, Kenneth A.
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Pyrophosphate release acts as a kinetic checkpoint during high-fidelity DNA replication by the Staphylococcus aureus replicative polymerase PolC
NUCLEIC ACIDS RESEARCH
IF
13.1
2021-07-24
13
OA
AI
Fagan, Sean P.; Mukherjee, Purba; Jaremko, William J.; Nelson-Rigg, Rachel; Wilson, Ryan C.; Dangerfield, Tyler L.; Johnson, Kenneth A.; Lahiri, Indrajit; Pata, Janice D.
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Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication
MOLECULAR CELL
IF
16.6
2021-04-01
102
OA
AI
Bravo, Jack P. K.; Dangerfield, Tyler L.; Taylor, David W.; Johnson, Kenneth A.
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Kinetic and thermodynamic analysis defines roles for two metal ions in DNA polymerase specificity and catalysis
JOURNAL OF BIOLOGICAL CHEMISTRY
IF
3.9
2021-01-01
10
OA
AI
Gong, Shanzhong; Kirmizialtin, Serdal; Chang, Adrienne; Mayfield, Joshua E.; Zhang, Yan Jessie; Johnson, Kenneth A.
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Conformational dynamics during high-fidelity DNA replication and translocation defined using a DNA polymerase with a fluorescent artificial amino acid
JOURNAL OF BIOLOGICAL CHEMISTRY
IF
3.9
2021-01-01
16
OA
AI
Dangerfield, Tyler L.; Johnson, Kenneth A.
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Conformational Dynamics Contribute to Substrate Selectivity and Catalysis in Human Kynureninase
ACS CHEMICAL BIOLOGY
IF
3.8
2020-12-04
7
OA
AI
Karamitros, Christos S.; Murray, Kyle; Sugiyama, Yusuke; Kumada, Yoichi; Johnson, Kenneth A.; Georgiou, George; D'Arcy, Sheena; Stone, Everett M.
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Optimized incorporation of an unnatural fluorescent amino acid affords measurement of conformational dynamics governing high-fidelity DNA replication
JOURNAL OF BIOLOGICAL CHEMISTRY
IF
3.9
2020-12-01
16
OA
AI
Dangerfield, Tyler L.; Johnson, Kenneth A.
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Rate-limiting pyrophosphate release by hepatitis C virus polymerase NS5B improves fidelity
JOURNAL OF BIOLOGICAL CHEMISTRY
IF
3.9
2020-11-01
6
OA
AI
Villalba, Brian; Johnson, Kenneth A.
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Engineered CRISPR/Cas9 enzymes improve discrimination by slowing DNA cleavage to allow release of off-target DNA
NATURE COMMUNICATIONS
IF
15.7
2020-07-17
69
OA
AI
Liu, Mu-Sen; Gong, Shanzhong; Yu, Helen-Hong; Jung, Kyungseok; Johnson, Kenneth A.; Taylor, David W.
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研究方向
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A
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G
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H 指数: 101 · 论文数: 489
S
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H 指数: 92 · 论文数: 565
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