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R

Robin F. Irvine

University of Cambridge

81H指数
313论文数
3.6W被引数
收录论文 41
发表时间
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Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein
errELIFE
IF0
err2017-12-26
err52
errOAAI
errAl-Ramahi, Ismael; Giridharan, Sai Srinivas Panapakkam; Chen, Yu-Chi; Patnaik, Samarjit; Safren, Nathaniel; Hasegawa, Junya; de Haro, Maria; Gee, Amanda K. Wagner; Titus, Steven A.; Jeong, Hyunkyung; Clarke, Jonathan; Krainc, Dimitri; Zheng, Wei; Irvine, Robin F.; Barmada, Sami; Ferrer, Marc; Southall, Noel; Weisman, Lois S.; Botas, Juan; Marugan, Juan Jose
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In B cells, phosphatidylinositol 5-phosphate 4-kinase-α synthesizes PI(4,5)P2 to impact mTORC2 and Akt signaling在b细胞中，磷脂酰肌醇5-磷酸4-激酶-α 合成PI(4,5)P2以影响mTORC2和Akt信号传导
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2016-09-06
err20
errOAAI
errBulley, Simon J.; Droubi, Alaa; Clarke, Jonathan H.; Anderson, Karen E.; Stephens, Len R.; Hawkins, Phillip T.; Irvine, Robin F.
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Nuclear localizations of phosphatidylinositol 5-phosphate 4-kinases α and β are dynamic and independently regulated during starvation-induced stress在饥饿诱导的压力下，磷脂酰肌醇5-磷酸4-激酶 α 和 β 的核定位是动态且独立调节的
errBIOCHEMICAL JOURNAL
IF4.3
err2016-07-12
err3
errOAAI
errDroubi, Alaa; Bulley, Simon J.; Clarke, Jonathan H.; Irvine, Robin F.
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The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site使用靶向PI5P-binding位点的特异性抑制剂探索磷脂酰肌醇5-磷酸4-激酶 γ (PI5P4Kγ) 的功能
errBIOCHEMICAL JOURNAL
IF4.3
err2015-02-20
err37
errOAAI
errClarke, Jonathan H.; Giudici, Maria-Luisa; Burke, John E.; Williams, Roger L.; Maloney, David J.; Marugan, Juan; Irvine, Robin F.
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Enzyme activity of the PIP4K2A gene product polymorphism that is implicated in schizophrenia
errPSYCHOPHARMACOLOGY
IF3.3
err2013-10-01
err10
errOAAI
errClarke, Jonathan H.; Irvine, Robin F.
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Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization
errBIOCHEMICAL JOURNAL
IF4.3
err2013-07-26
err52
errOAAI
errClarke, Jonathan H.; Irvine, Robin F.
err分享
err收藏
Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases IIα and IIβ and a partial nuclear localization of the IIα isoform
errBIOCHEMICAL JOURNAL
IF4.3
err2010-08-13
err43
errOAAI
errWang, Minchuan; Bond, Nicholas J.; Letcher, Andrew J.; Richardson, Jonathan P.; Lilley, Kathryn S.; Irvine, Robin F.; Clarke, Jonathan H.
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Reversible binding and rapid diffusion of proteins in complex with inositol lipids serves to coordinate free movement with spatial information
errJOURNAL OF CELL BIOLOGY
IF6.4
err2009-01-19
err80
errOAAI
errHammond, Gerald R. V.; Sim, Yirong; Lagnado, Leon; Irvine, Robin F.
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Localization of phosphatidylinositol phosphate kinase IIγ in kidney to a membrane trafficking compartment within specialized cells of the nephron
errAMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
IF3.4
err2008-11-01
err56
errOAAI
errClarke, Jonathan H.; Emson, Piers C.; Irvine, Robin F.
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Genomic tagging of endogenous Type IIβ phosphatidylinositol 5-phosphate 4-kinase in DT40 cells reveals a nuclear localisation
errCELLULAR SIGNALLING
IF3.7
err2007-06-01
err31
errOAAI
errRichardson, Jonathan P.; Wang, Minchuan; Clarke, Jonathan H.; Patel, Ketan J.; Irvine, R. F.
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Regulation of inositol 1,4,5-trisphosphate 3-kinases by calcium and localization in cells
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2007-03-01
err19
errOAAI
errLloyd-Burton, Samantha M.; Yu, Jowie C. H.; Irvine, Robin F.; Schell, Michael J.
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The intracellular localisation and mobility of Type Iγ phosphatidylinositol 4P 5-kinase splice variants
errFEBS LETTERS
IF3
err2006-11-30
err26
errOAAI
errGiudici, Maria-Luisa; Lee, Koon; Lim, Rongxuan; Irvine, Robin F.
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The behaviour of myo-inositol hexakisphosphate in the presence of magnesium(II) and calcium(II):: Protein-free soluble InsP6 is limited to 49 μM under cytosolic/nuclear conditions
errJOURNAL OF INORGANIC BIOCHEMISTRY
IF3.2
err2006-11-01
err74
errOAAI
errVeiga, Nicolas; Torres, Julia; Dominguez, Sixto; Mederos, Alfredo; Irvine, Robin F.; Diaz, Alvaro; Kremer, Carlos
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Regulation of the localization and activity of inositol 1,4,5-trisphosphate 3-kinase B in intact cells by proteolysis
errBIOCHEMICAL JOURNAL
IF4.3
err2005-12-06
err15
errOAAI
errYu, JCH; Lloyd-Burton, SM; Irvine, RF; Schell, MJ
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Agonist-induced regulation of mitochondrial and endoplasmic reticulum motility
errBIOCHEMICAL JOURNAL
IF4.3
err2005-11-22
err85
errOAAI
errBrough, D; Schell, MJ; Irvine, RF
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The structural integrity of the endoplasmic reticulum, and its possible regulation by inositol 1,3,4,5-tetrakisphosphate
errCELL CALCIUM
IF4
err2005-08-01
err12
PREAI
errBrough, D; Sim, Y; Thorn, P; Irvine, RF
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Mobility of proteins associated with the plasma membrane by interaction with inositol lipids
errJOURNAL OF CELL SCIENCE
IF3.6
err2005-07-15
err25
errOAAI
errBrough, D; Bhatti, F; Irvine, RF
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Phospholipase D2 stimulates integrin-mediated adhesion via phosphatidylinositol 4-phosphate 5-kinase Iγb
errJOURNAL OF CELL SCIENCE
IF3.6
err2005-07-01
err51
PREAI
errPowner, DJ; Payne, RM; Pettitt, TR; Gludici, ML; Irvine, RF; Wakelam, MJO
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Effects of lipid kinase expression and cellular stimuli on phosphatidylinositol 5-phosphate levels in mammalian cell lines
errFEBS LETTERS
IF3
err2005-04-27
err46
PREAI
errRoberts, HF; Clarke, JH; Letcher, AJ; Irvine, RF; Hinchliffe, KA
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Solution behaviour of myo-inositol hexakisphosphate in the presence of multivalent cations.: Prediction of a neutral pentainagnesium species under cytosolic/nuclear conditions
errJOURNAL OF INORGANIC BIOCHEMISTRY
IF3.2
err2005-03-01
err176
PREAI
errTorres, J; Domínguez, S; Cerdá, MF; Obal, G; Mederos, A; Irvine, RF; Díaz, A; Kremer, C
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研究方向

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合作学者
合作期刊
R
Roger Williams
H 指数: 125 · 论文数: 1.2K
K
Kathryn S. Lilley
H 指数: 87 · 论文数: 422
Y
Young‐Tae Chang
H 指数: 84 · 论文数: 638
P
Phillip T. Hawkins
H 指数: 76 · 论文数: 259
L
Len Stephens
H 指数: 76 · 论文数: 227
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