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Targeting the complement lectin pathway with a highly specific MASP-2 inhibitor protects against renal ischemia-reperfusion injury 靶向凝集素途径的MASP-2特异性抑制剂可保护肾脏缺血再灌注损伤 Bongoni, Anjan K.; Kiss, Bence; McRae, Jennifer L.; Salvaris, Evelyn J.; Fisicaro, Nella; Muntz, Fenella; Nemeth, Balint Zoltan; Nagy, Zoltan Attila; Kocsis, Andrea; Gal, Peter; Cowan, Peter J. 分享 收藏
Praziquantel and factor H recruitment differentially affect the susceptibility of Schistosoma mansoni to complement-mediated damage van Beek, Anna E.; Jeanguenat, Hannah; Haberli, Cecile; Pouw, Richard B.; Lamers, Christina; Pal, Gabor; Gal, Peter; Schmidt, Christoph Q.; Ricklin, Daniel; Keiser, Jennifer 分享 收藏
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Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation Nagy, Zoltan Attila; Heja, David; Bencze, Daniel; Kiss, Bence; Boros, Eszter; Szakacs, David; Fodor, Krisztian; Wilmanns, Matthias; Kocsis, Andrea; Dobo, Jozsef; Gal, Peter; Harmat, Veronika; Pal, Gabor 分享 收藏
Directed Evolution-Driven Increase of Structural Plasticity Is a Prerequisite for Binding the Complement Lectin Pathway Blocking MASP-Inhibitor Peptides Durvanger, Zsolt; Boros, Eszter; Nagy, Zoltan Attila; Hegedus, Rozsa; Megyeri, Marton; Dobo, Jozsef; Gal, Peter; Schlosser, Gitta; Angyan, Annamaria F.; Gaspari, Zoltan; Perczel, Andras; Harmat, Veronika; Mezo, Gabor; Menyhard, Dora K.; Pal, Gabor 分享 收藏
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Proprotein Convertase Is the Highest-Level Activator of the Alternative Complement Pathway in the Blood Oroszlan, Gabor; Dani, Rahel; Vegh, Barbara M.; Varga, Dora; Acs, Andrea, V; Pal, Gabor; Zavodszky, Peter; Farkas, Henriette; Gal, Peter; Dobo, Jozsef 分享 收藏
Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PL A2R1-associated membranous nephropathy Haddad, George; Lorenzen, Johan M.; Ma, Hong; Haan, Noortje de; Seeger, Harald; Zaghrini, Christelle; Brandt, Simone; Kolling, Malte; Wegmann, Urs; Kiss, Bence; Pal, Gabor; Gal, Peter; Wuthrich, Rudolf P.; Wuhrer, Manfred; Beck, Laurence H.; Salant, David J.; Lambeau, Gerard; Kistler, Andreas D. 分享 收藏
ITIH4 acts as a protease inhibitor by a novel inhibitory mechanism Pihl, Rasmus; Jensen, Rasmus K.; Poulsen, Emil C.; Jensen, Lisbeth; Hansen, Annette G.; Thogersen, Ida B.; Dobo, Jozsef; Gal, Peter; Andersen, Gregers R.; Enghild, Jan J.; Thiel, Steffen 分享 收藏
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Ecotin, a microbial inhibitor of serine proteases, blocks multiple complement dependent and independent microbicidal activities of human serum Nagy, Zoltan Attila; Szakacs, David; Boros, Eszter; Heja, David; Vigh, Eszter; Sandor, Noemi; Jozsi, Mihaly; Oroszlan, Gabor; Dobo, Jozsef; Gal, Peter; Pal, Gabor 分享 收藏
Design and Selection of Novel C1s Inhibitors by In Silico and In Vitro Approaches Szilagyi, Katalin; Hajdu, Istvan; Flachner, Beata; Lorincz, Zsolt; Balczer, Julia; Gal, Peter; Zavodszky, Peter; Pirli, Chiara; Balogh, Balazs; Mandity, Istvan M.; Cseh, Sandor; Dorman, Gyorgy 分享 收藏
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Cutting Edge: A New Player in the Alternative Complement Pathway, MASP-1 Is Essential for LPS-Induced, but Not for Zymosan-Induced, Alternative Pathway Activation Parej, Katalin; Kocsis, Andrea; Enyingi, Csenge; Dani, Rahel; Oroszlan, Gabor; Beinrohr, Laszlo; Dobo, Jozsef; Zavodszky, Peter; Pal, Gabor; Gal, Peter 分享 收藏
Complement MASP-1 enhances adhesion between endothelial cells and neutrophils by up-regulating E-selectin expression Jani, Peter K.; Schwaner, Endre; Kajdacsi, Erika; Debreczeni, Marta L.; Ungai-Salanki, Rita; Dobo, Jozsef; Doleschall, Zoltan; Rigo, Janos, Jr.; Geiszt, Miklos; Szabo, Balint; Gal, Peter; Cervenak, Laszlo 分享 收藏
Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis Pilely, Katrine; Rosbjerg, Anne; Genster, Ninette; Gal, Peter; Pal, Gabor; Halvorsen, Bente; Holm, Sverre; Aukrust, Pal; Bakke, Siril Skaret; Sporsheim, Bjornar; Nervik, Ingunn; Niyonzima, Nathalie; Bartels, Emil D.; Stahl, Gregory L.; Mollnes, Tom Eirik; Espevik, Terje; Garred, Peter 分享 收藏
MASP-1 and MASP-2 Do Not Activate Pro-Factor D in Resting Human Blood, whereas MASP-3 Is a Potential Activator: Kinetic Analysis Involving Specific MASP-1 and MASP-2 Inhibitors Oroszlan, Gabor; Kortvely, Elod; Szakacs, David; Kocsis, Andrea; dammeier, Sascha; Zeck, Anne; Ueffing, Marius; Zavodszky, Peter; Pal, Gabor; Gal, Peter; Dobo, Jozsef 分享 收藏
Quantitative Characterization of the Activation Steps of Mannan-binding Lectin (MBL)-associated Serine Proteases (MASPs) Points to the Central Role of MASP-1 in the Initiation of the Complement Lectin Pathway Megyeri, Marton; Harmat, Veronika; Major, Balazs; Vegh, Adam; Balczer, Julia; Heja, David; Szilagyi, Katalin; Datz, Daniel; Pal, Gabor; Zavodszky, Peter; Gal, Peter; Dobo, Jozsef 分享 收藏
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