未登录The Landscape of Early Clinical Gene Therapies outside of Oncology
Rittie, Laure; Athanasopoulos, Takis; Calero-Garcia, Miguel; Davies, Marie L.; Dow, David J.; Howe, Steven J.; Morrison, Alastair; Ricciardelli, Ida; Saudemont, Aurore; Jespers, Laurent; Clay, Timothy M. .png)
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收藏Polyfunctional anti-human epidermal growth factor receptor 3 (anti-HER3) antibodies induced by HER3 vaccines have multiple mechanisms of antitumor activity against therapy resistant and triple negative breast cancersOsada, Takuya; Hartman, Zachary C.; Wei, Junping; Lei, Gangjun; Hobeika, Amy C.; Gwin, William R.; Diniz, Marcio A.; Spector, Neil; Clay, Timothy M.; Chen, Wei; Morse, Michael A.; Lyerly, H. Kim 分享 收藏 分享 收藏 A Randomized Phase II Study of Immunization With Dendritic Cells Modified With Poxvectors Encoding CEA and MUC1 Compared With the Same Poxvectors Plus GM-CSF for Resected Metastatic Colorectal CancerMorse, Michael A.; Niedzwiecki, Donna; Marshall, John L.; Garrett, Christopher; Chang, David Z.; Aklilu, Mebea; Crocenzi, Todd S.; Cole, David J.; Dessureault, Sophie; Hobeika, Amy C.; Osada, Takuya; Onaitis, Mark; Clary, Bryan M.; Hsu, David; Devi, Gayathri R.; Bulusu, Anuradha; Annechiarico, Robert P.; Chadaram, Vijaya; Clay, Timothy M.; Lyerly, H. Kim 分享 收藏 phase 1 clinical trial of HER2-specific immunotherapy with concomitant HER2 kinase inhibtion (vol 10, pg 28, 2012)Hamilton, Erika; Blackwell, Kimberly; Hobeika, Amy C.; Clay, Timothy M.; Broadwater, Gloria; Ren, Xiu-Rong; Chen, Wei; Castro, Henry; Lehmann, Frederic; Spector, Neil; Wei, Junping; Osada, Takuya; Lyerly, H. Kim; Morse, Michael A. 分享 收藏 Polyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cellsRen, Xiu-Rong; Wei, Junping; Lei, Gangjun; Wang, Jiangbo; Lu, Jiuyi; Xia, Wenle; Spector, Neil; Barak, Larry S.; Clay, Timothy M.; Osada, Takuya; Hamilton, Erika; Blackwell, Kimberly; Hobeika, Amy C.; Morse, Michael A.; Lyerly, H. Kim; Chen, Wei 分享 收藏 Phase I clinical trial of HER2-specific immunotherapy with concomitant HER2 kinase inhibtionHamilton, Erika; Blackwell, Kimberly; Hobeika, Amy C.; Clay, Timothy M.; Broadwater, Gloria; Ren, Xiu-Rong; Chen, Wei; Castro, Henry; Lehmann, Frederic; Spector, Neil; Wei, Junping; Osada, Takuya; Lyerly, H. Kim 分享 收藏 Truncated ErbB2 Expressed in Tumor Cell Nuclei Contributes to Acquired Therapeutic Resistance to ErbB2 Kinase InhibitorsXia, Wenle; Liu, Zuguo; Zong, Rongrong; Liu, Leihua; Zhao, Sumin; Bacus, Sarah S.; Mao, Yubin; He, Jia; Wulfkuhle, Julia D.; Petricoin, Emanuel F., III; Osada, Takuya; Yang, Xiao-Yi; Hartman, Zachary C.; Clay, Timothy M.; Blackwell, Kimberly L.; Lyerly, Herbert K.; Spector, Neil L. 分享 收藏 分享 收藏 Antihelminth Compound Niclosamide Downregulates Wnt Signaling and Elicits Antitumor Responses in Tumors with Activating APC MutationsOsada, Takuya; Chen, Minyong; Yang, Xiao Yi; Spasojevic, Ivan; Vandeusen, Jeffrey B.; Hsu, David; Clary, Bryan M.; Clay, Timothy M.; Chen, Wei; Morse, Michael A.; Lyerly, H. Kim 分享 收藏 MHC Class I-Presented Tumor Antigens Identified in Ovarian Cancer by Immunoproteomic Analysis Are Targets for T-Cell Responses against Breast and Ovarian CancerMorse, Michael A.; Secord, Angeles A.; Blackwell, Kimberly; Hobeika, Amy C.; Sinnathamby, Gomathinayagam; Osada, Takuya; Hafner, Julie; Philip, Mohan; Clay, Timothy M.; Lyerly, H. Kim; Philip, Ramila 分享 收藏 分享 收藏 CSPG4 Protein as a New Target for the Antibody-Based Immunotherapy of Triple-Negative Breast CancerWang, Xinhui; Osada, Takuya; Wang, Yangyang; Yu, Ling; Sakakura, Koichi; Katayama, Akihiro; McCarthy, James B.; Brufsky, Adam; Chivukula, Mamatha; Khoury, Thaer; Hsu, David S.; Barry, William T.; Lyerly, H. Kim; Clay, Timothy M.; Ferrone, Soldano 分享 收藏 分享 收藏 An alphavirus vector overcomes the presence of neutralizing antibodies and elevated numbers of Tregs to induce immune responses in humans with advanced cancerMorse, Michael A.; Hobeika, Amy C.; Osada, Takuya; Berglund, Peter; Hubby, Bolyn; Negri, Sarah; Niedzwiecki, Donna; Devi, Gayathri R.; Burnett, Bruce K.; Clay, Timothy M.; Smith, Jonathan; Lyerly, H. Kim 分享 收藏 Synergism from combined immunologic and pharmacologic inhibition of HER2 in vivoMorse, Michael A.; Wei, Junping; Hartman, Zachary; Xia, Wenle; Ren, Xiu-Rong; Lei, Gangjun; Barry, William T.; Osada, Takuya; Hobeika, Amy C.; Peplinski, Sharon; Jiang, Haixiang; Devi, Gayathri R.; Chen, Wei; Spector, Neil; Amalfitano, Andrea; Lyerly, H. Kim; Clay, Timothy M. 分享 收藏 分享 收藏 An Adenoviral Vaccine Encoding Full-Length Inactivated Human Her2 Exhibits Potent Immunogenicty and Enhanced Therapeutic Efficacy without OncogenicityHartman, Zachary C.; Wei, Junping; Osada, Takuya; Glass, Oliver; Lei, Gangjun; Yang, Xiao-Yi; Peplinski, Sharon; Kim, Dong-Wan; Xia, Wenle; Spector, Neil; Marks, Jeffrey; Barry, William; Hobeika, Amy; Devi, Gayathri; Amalfitano, Andrea; Morse, Michael A.; Lyerly, H. Kim; Clay, Timothy M. 分享 收藏 Immunomodulatory Gene Therapy Prevents Antibody Formation and Lethal Hypersensitivity Reactions in Murine Pompe DiseaseSun, Baodong; Kulis, Michael D.; Young, Sarah P.; Hobeika, Amy C.; Li, Songtao; Bird, Andrew; Zhang, Haoyue; Li, Yifan; Clay, Timothy M.; Burks, Wesley; Kishnani, Priya S.; Koeberl, Dwight D. 分享 收藏 分享 收藏 
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