Lina M. Obeid - Publications, H-index & Citations

Lina M. Obeid

University of Hawaii Manoa

102H指数

374论文数

3.6W被引数

收录论文 32

发表时间

Retention of lysosomal acid sphingomyelinase protects from Niemann-Pick Disease 溶酶体酸性鞘磷脂酶的保留可保护免受尼曼-皮克病的侵害。

Neurobiology of Disease

IF5.6

2025-10-15

OAAI

Cameron A. Beard; Kyra N. Hermanson; Justin M. Snider; Aki Hara; Brandon K. Dahl; Janet J. Allopenna; Marilyn T. Marron; Benjamin Newcomb; Benjamin E. Low; Michael V. Wiles; Russell W. Jenkins; Lina M. Obeid; Yusuf A. Hannun; Ashley J. Snider

Expression of Ceramide Synthases in Mice and Their Roles in Regulating Acyl-Chain Sphingolipids: A Framework for Baseline Levels and Future Implications in Aging and Disease

MOLECULAR PHARMACOLOGY

IF3

2024-03-01

OAAI

Richardson, Whitney J.; Humphrey, Sophia B.; Sears, Sophia M.; Hoffman, Nicholas A.; Orwick, Andrew J.; Doll, Mark A.; Doll, Chelsea L.; Xia, Catherine; Hernandez-Corbacho, Maria; Snider, Justin M.; Obeid, Lina M.; Hannun, Yusuf A.; Snider, Ashley J.; Siskind, Leah J.

Targeting sphingosine kinase 1 in p53KO thymic lymphoma

FASEB JOURNAL

IF4.2

2023-10-06

OAAI

Velazquez, Fabiola N.; Stith, Jeffrey L.; Zhang, Leiqing; Allam, Amira M.; Haley, John; Obeid, Lina M.; Snider, Ashley J.; Hannun, Yusuf A.

The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation

CELL REPORTS

IF6.9

2023-09-01

OAAI

Boyd, Rowan A.; Majumder, Saurav; Stiban, Johnny; Mavodza, Grace; Straus, Alexandra J.; Kempelingaiah, Sachin K.; Reddy, Varun; Hannun, Yusuf A.; Obeid, Lina M.; Senkal, Can E.

Ceramide as an endothelial cell surface receptor and a lung- specific lipid vascular target for circulating ligands

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2023-08-14

OAAI

Staquicini, Daniela I.; Cardo-Vila, Marina; Rotolo, Jimmy A.; Staquicini, Fernanda I.; Tang, Fenny H. F.; Smith, Tracey L.; Ganju, Aditya; Schiavone, Carmine; Dogra, Prashant; Wang, Zhihui; Cristini, Vittorio; Giordano, Ricardo J.; Ozawa, Michael G.; Driessen, Wouter H. P.; Proneth, Bettina; Souza, Glauco R.; Brinker, Lina M.; Noureddine, Achraf; Snider, Ashley J.; Canals, Daniel; Gelovani, Juri G.; Petrache, Irina; Tuder, Rubin M.; Obeid, Lina M.; Hannun, Yusuf A.; Kolesnick, Richard N.; Brinker, C. Jeffrey; Pasqualini, Renata; Arap, Wadih

Upregulation of sphingosine kinase 1 in response to doxorubicin generates an angiogenic response via stabilization of Snail

FASEB JOURNAL

IF4.2

2023-02-01

OAAI

Bonica, Joseph; Clarke, Christopher J.; Obeid, Lina M.; Luberto, Chiara; Hannun, Yusuf A.

Neutral ceramidase deficiency protects against cisplatin-induced acute kidney injury

JOURNAL OF LIPID RESEARCH

IF4.1

2022-03-01

OAAI

Sears, Sophia M.; Dupre, Tess, V; Shah, Parag P.; Davis, Deanna L.; Doll, Mark A.; Sharp, Cierra N.; Vega, Alexis A.; Megyesi, Judit; Beverly, Levi J.; Snider, Ashley J.; Obeid, Lina M.; Hannun, Yusuf A.; Siskind, Leah J.

1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase

JOURNAL OF LIPID RESEARCH

IF4.1

2022-01-01

OAAI

Truman, Jean-Philip; Ruiz, Christian F.; Montal, Emily; Garcia-Barros, Monica; Mileva, Izolda; Snider, Ashley J.; Hannun, Yusuf A.; Obeid, Lina M.; Mao, Cungui

GRASP55 regulates intra-Golgi localization of glycosylation enzymes to control glycosphingolipid biosynthesis

EMBO JOURNAL

IF8.3

2021-09-13

OAAI

Pothukuchi, Prathyush; Agliarulo, Ilenia; Pirozzi, Marinella; Rizzo, Riccardo; Russo, Domenico; Turacchio, Gabriele; Nuechel, Julian; Yang, Jia-Shu; Gehin, Charlotte; Capolupo, Laura; Hernandez-Corbacho, Maria Jose; Biswas, Ansuman; Vanacore, Giovanna; Dathan, Nina; Nitta, Takahiro; Henklein, Petra; Thattai, Mukund; Inokuchi, Jin-Ichi; Hsu, Victor W.; Plomann, Markus; Obeid, Lina M.; Hannun, Yusuf A.; Luini, Alberto; D'Angelo, Giovanni; Parashuraman, Seetharaman

A Milk-Fat Based Diet Increases Metastasis in the MMTV-PyMT Mouse Model of Breast Cancer

NUTRIENTS

IF5

2021-07-15

OAAI

Velazquez, Fabiola N.; Viscardi, Valentina; Montemage, Julia; Zhang, Leiqing; Trocchia, Carolena; Delamont, Megan M.; Ahmad, Rasheed; Hannun, Yusuf A.; Obeid, Lina M.; Snider, Ashley J.

Sphingosine kinase 1 downregulation is required for adaptation to serine deprivation

FASEB JOURNAL

IF4.2

2021-01-23

OAAI

Truman, Jean-Philip; Ruiz, Christian F.; Trayssac, Magali; Mao, Cungui; Hannun, Yusuf A.; Obeid, Lina M.

Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides

CELL DEATH & DISEASE

IF9.6

2021-01-04

OAAI

Trayssac, Magali; Clarke, Christopher J.; Stith, Jeffrey L.; Snider, Justin M.; Newen, Naomi; Gault, Christopher R.; Hannun, Yusuf A.; Obeid, Lina M.

Transcriptional Regulation of Sphingosine Kinase 1

CELLS

IF5.2

2020-11-08

OAAI

Bonica, Joseph; Mao, Cungui; Obeid, Lina M.; Hannun, Yusuf A.

Probing compartment-specific sphingolipids with targeted bacterial sphingomyelinases and ceramidases[S]

JOURNAL OF LIPID RESEARCH

IF4.1

2019-11-01

OAAI

Sakamoto, Wataru; Canals, Daniel; Salamone, Silvia; Allopenna, Janet; Clarke, Christopher J.; Snider, Justin; Obeid, Lina M.; Hannun, Yusuf A.

PKCα is required for Akt-mTORC1 activation in non-small cell lung carcinoma (NSCLC) with EGFR mutation (vol 38, pg 7311, 2019)

ONCOGENE

IF7.3

2019-10-01

OAAI

Salama, Mohamed F.; Liu, Mengling; Clarke, Christopher J.; Espaillat, Mel Pilar; Haley, John D.; Jin, Ting; Wang, Daifeng; Obeid, Lina M.; Hannun, Yusuf A.

PKCα is required for Akt-mTORC1 activation in non-small cell lung carcinoma (NSCLC) with EGFR mutation

ONCOGENE

IF7.3

2019-08-16

OAAI

Salama, Mohamed F.; Liu, Mengling; Clarke, Christopher J.; Espaillat, Mel Pilar; Haley, John D.; Jin, Ting; Wang, Daifeng; Obeid, Lina M.; Hannun, Yusuf A.

Multiple actions of doxorubicin on the sphingolipid network revealed by flux analysis

JOURNAL OF LIPID RESEARCH

IF4.1

2019-04-01

OAAI

Snider, Justin M.; Trayssac, Magali; Clarke, Christopher J.; Schwartz, Nicholas; Snider, Ashley J.; Obeid, Lina M.; Luberto, Chiara; Hannun, Yusuf A.

Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways 长链酰基辅酶a合成酶1与激活和引导脂肪酸进入利基肝途径的关键蛋白相互作用

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-10-01

OAAI

Young, Pamela A.; Senkal, Can E.; Suchanek, Amanda L.; Grevengoed, Trisha J.; Lin, Dennis D.; Zhao, Liyang; Crunk, Amanda E.; Klett, Eric L.; Fuellekrug, Joachim; Obeid, Lina M.; Coleman, Rosalind A.

Sphingosine Kinase 1 expression in peritoneal macrophages is required for colon carcinogenesis

CARCINOGENESIS

IF2.9

2017-09-23

OAAI

Furuya, Hideki; Tamashiro, Paulette M.; Shimizu, Yoshiko; Iino, Kayoko; Peres, Rafael; Chen, Runpu; Sun, Yijun; Hannun, Yusuf A.; Obeid, Lina M.; Kawamori, Toshihiko

P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment

ONCOGENE

IF7.3

2017-08-07

OAAI

Wada, M.; Canals, D.; Adada, M.; Coant, N.; Salama, M. F.; Helke, K. L.; Arthur, J. S.; Shroyer, K. R.; Kitatani, K.; Obeid, L. M.; Hannun, Y. A.

研究方向