未登录Improved iGAL 2.0 Metric Empowers Pharmaceutical Scientists to Make Meaningful Contributions to United Nations Sustainable Development Goal 12
Roschangar, Frank; Li, Jun; Zhou, Yanyan; Aelterman, Wim; Borovika, Alina; Colberg, Juan; Dickson, David P.; Gallou, Fabrice; Hayler, John D.; Koenig, Stefan G.; Kopach, Michael E.; Kosjek, Birgit; Leahy, David K.; O'Brien, Erin; Smith, Austin G.; Henry, Manuel; Cook, Jutta; Sheldon, Roger A.
分享
收藏
分享
收藏
分享
收藏
分享
收藏
分享
收藏
分享
收藏Regio- and diastereoselective ring-opening of (S)-(-)-2-(trifluoromethyl)oxirane with chiral 2,5-disubstituted tetrahydroquinolines in hexafluoro-2-propanol
Li, Xun; Russell, Ronald K.; Chen, Hongfeng; Zhang, Yongzheng; Ballentine, Scott; Spink, Jan; Branum, Shawn; Liu, Fuqiang; Chen, Yanping; Rammeloo, Thomas; Aelterman, Wim; Sorgi, Kirk L.; Murray, William V.
分享
收藏
分享
收藏
分享
收藏Synthesis of Tetracyclic Heterocompounds as Selective Estrogen Receptor Modulators. Part 3. Development of an Acid-Catalyzed Racemization Process for (S)-2,8-(Dimethoxy)-5-{4-[2-(1-piperidinyl)ethoxy]-phenyl}-11,12-dihydro-5H-6,13-dioxabenzo[3,4]cyclohepta[1,2-a]naphthalene
Li, Xun; Russell, Ronald K.; Horvath, Andras; Jain, Nareshkumar; Depre, Dominique; Ormerod, Dominic; Aelterman, Wim; Sui, Zhihua
分享
收藏
分享
收藏
分享
收藏Development of a scalable and safe procedure for the production of (3R)-3-(2,3-dihydro-1-benzofuran-5-yl)-1,2,3,4-tetrahydro-9H-pyrrolo[3,4-b]-quinolin-9-one, an intermediate in the synthesis of PDE-V inhibitors RWJ387273 (R301249) and RWJ444772 (R290629)
Willemsens, Bert; Vervest, Ivan; Ormerod, Dominic; Aelterman, Wim; Fannes, Christine; Mertens, Narda; Marko, Istvan E.; Lemaire, Sebastien
分享
收藏Convenient synthesis of 3,4-methano-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and its derivatives as doubly constrained nonproteinogenic amino acid derivatives
Czombos, J; Aelterman, W; Tkachev, A; Martins, JC; Tourwé, D; Péter, A; Tóth, G; Fülöp, F; De Kimpe, N
分享
收藏
分享
收藏