未登录Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy
Woo, Caroline J.; Maier, Verena K.; Davey, Roshni; Brennan, James; Li, Guangde; Brothers, John, II; Schwartz, Brian; Gordo, Susana; Kasper, Anne; Okamoto, Trevor R.; Johansson, Hans E.; Mandefro, Berhan; Sareen, Dhruv; Bialek, Peter; Chau, B. Nelson; Bhat, Balkrishen; Bullough, David; Barsoum, James .png)
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收藏The Vascular Disrupting Agent STA-9584 Exhibits Potent Antitumor Activity by Selectively Targeting Microvasculature at Both the Center and Periphery of TumorsFoley, Kevin P.; Zhou, Dan; Borella, Chris; Wu, Yaming; Zhang, Mei; Jiang, Jun; Li, Hao; Sang, Jim; Korbut, Tim; Ye, Josephine; Zhang, Xuemei; Barsoum, James; Sonderfan, Andrew J. 分享 收藏 Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in In Vitro and In Vivo Models of Non-Small Cell Lung CancerShimamura, Takeshi; Perera, Samanthi A.; Foley, Kevin P.; Sang, Jim; Rodig, Scott J.; Inoue, Takayo; Chen, Liang; Li, Danan; Carretero, Julian; Li, Yu-Chen; Sinha, Papiya; Carey, Christopher D.; Borgman, Christa L.; Jimenez, John-Paul; Meyerson, Matthew; Ying, Weiwen; Barsoum, James; Wong, Kwok-Kin; Shapiro, Geoffrey I. 分享 收藏 The oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cellsNagai, Masazumi; Vo, Nha H.; Ogawa, Luisa Shin; Chimmanamada, Dinesh; Inoue, Takayo; Chu, John; Beaudette-Zlatanova, Britte C.; Lu, Rongzhen; Blackman, Ronald K.; Barsoum, James; Koya, Keizo; Wada, Yumiko 分享 收藏 Ganetespib, a Unique Triazolone-Containing Hsp90 Inhibitor, Exhibits Potent Antitumor Activity and a Superior Safety Profile for Cancer TherapyYing, Weiwen; Du, Zhenjian; Sun, Lijun; Foley, Kevin P.; Proia, David A.; Blackman, Ronald K.; Zhou, Dan; Inoue, Takayo; Tatsuta, Noriaki; Sang, Jim; Ye, Shuxia; Acquaviva, Jamie; Ogawa, Luisa Shin; Wada, Yumiko; Barsoum, James; Koya, Keizo 分享 收藏 Phase I evaluation of STA-1474, a pro-drug of the novel HSP90 inhibitor STA-9090, in dogs with spontaneous cancerLondon, Cheryl A.; Bear, Misty D.; McCleese, Jennifer; Foley, Kevin P.; Paalangara, Reji; Inoue, Takayo; Ying, Weiwen; Barsoum, James 分享 收藏 Pharmacodynamic analysis of the Hsp90 inhibitor STA-9090 in a lung cancer xenograft model supports an infrequent dosing schedule in the clinicFoley, Kevin P.; Shimamura, Takeshi; Blackman, Ron K.; Borgman, Christa L.; Inoue, Takayo; Korbut, Tim; Proia, David; Sang, Jim; Ogawa, Luisa Shin; Smith, Don; Tatsuta, Noriaki; Zhang, Chaohua; Zhang, Haili; Ying, Weiwen; Shapiro, Geoffrey I.; Barsoum, James 分享 收藏 The oxidative stress inducer elesclomol requires copper chelation for its anticancer activityNagai, Masazumi; Vho, Nha; Kostik, Elena; He, Suqin; Kepros, Jane; Ogawa, Luisa S.; Inoue, Takayo; Blackman, Ronald K.; Wada, Yumiko; Barsoum, James 分享 收藏 In vitro and in vivo efficacy of the novel Hsp90 inhibitor STA-9090 and its synergy with pad itaxelYing, Weiwen; Blackman, Ronald K.; Chimmanamada, Dinesh; Du, Zhenjian; Foley, Kevin P.; He, Suqin; Inoue, Takayo; James, David; Kepros, Jane; Korbut, Tim; Ogawa, Luisa Shin; Peng, Cong; Przewloka, Teresa; Proia, David; Sang, Jim; Smith, Donald; Tatsuta, Noriaki; Yang, Chin-Yu; Zhang, Chaohua; Zhang, Haili; Zhang, Shijie; Li, Shaoguang; Barsoum, James 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Concurrent chemoradiation therapy with the oxidative stress inducer STA-4783 in mouse xenograft tumor modelsFoley, K. P.; Mihalek, R.; Korbut, T.; Sang, J.; Song, W.; Zhang, C.; Kirshner, J.; Du, Z.; Bertin, J.; Barsoum, J. 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 
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