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收藏Spermidine/spermine-N1-acetyltransferase ablation protects against liver and kidney ischemia-reperfusion injury in mice
Zahedi, Kamyar; Lentsch, Alex B.; Okaya, Tomohisa; Barone, Sharon; Sakai, Nozomu; Witte, David P.; Arend, Lois J.; Alhonen, Leena; Jell, Jason; Janne, Juhani; Porter, Carl W.; Soleimani, Manoocher
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收藏Genetically altered expression of spermidine/spermine N1-acetyltransferase affects fat metabolism in mice via acetyl-CoA
Jell, Jason; Merali, Salim; Hensen, Mary L.; Mazurchuk, Richard; Spernyak, Joseph A.; Diegelman, Paula; Kisiel, Nicholas D.; Barrero, Carlos; Deeb, Kristin K.; Alhonen, Leena; Patel, Mulchand S.; Porter, Carl W.
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收藏Spermidine/spermine N1-acetyltransferase overexpression in kidney epithelial cells disrupts polyamine homeostasis, leads to DNA damage, and causes G2 arrest
Zahedi, Kamyar; Bissler, John J.; Wang, Zhaohui; Josyula, Anuradha; Lu, Lu; Diegelman, Paula; Kisiel, Nick; Porter, Carl W.; Soleimani, Manoocher
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收藏Structural and functional evidence for Bacillus subtilis PaiA as a novel N1-spermidine/spermine acetyltransferase
Forouhar, F; Lee, IN; Vujcic, J; Vujcic, S; Shen, JW; Vorobiev, SM; Xiao, R; Acton, TB; Montelione, GT; Porter, CW; Liang, T
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收藏Potent modulation of intestinal tumorigenesis in Apcmin/+ mice by the polyamine catabolic enzyme spermidine/spermine N1-acetyltransferase
Tucker, JM; Murphy, JT; Kisiel, N; Diegelman, P; Barbour, KW; Davis, C; Medda, M; Alhonen, L; Jänne, J; Kramer, DL; Porter, CW; Berger, FG
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收藏Metabolic stability of α-methylated polyamine derivatives and their use as substitutes for the natural polyamines
Järvinen, A; Grigorenko, N; Khomutov, AR; Hyvönen, MT; Uimari, A; Vepsäläinen, J; Sinervirta, R; Keinänen, TA; Vujcic, S; Alhonen, L; Porter, CW; Jännet, J
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收藏Activated polyamine catabolism depletes acetyl-CoA pools and suppresses prostate tumor growth in TRAMP mice
Kee, K; Foster, BA; Merali, S; Kramer, DL; Hensen, ML; Diegelman, P; Kisiel, N; Vujcic, S; Mazurchuk, RV; Porter, CW
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收藏Clinical efficacy, tolerability, and safety of SAM486A, a novel polyamine biosynthesis inhibitor, in patients with relapsed or refractory non-Hodgkin's lymphoma:: Results from a phase II multicenter study
Pless, M; Belhadj, K; Menssen, HD; Kern, W; Coiffier, B; Wolf, J; Herrmann, R; Thiel, E; Bootle, D; Sklenar, I; Müller, C; Choi, L; Porter, C; Capdeville, R
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收藏Expression of SSAT, a novel biomarker of tubular cell damage, increases in kidney ischemia-reperfusion injury
Zahedi, K; Wang, ZH; Barone, S; Prada, AE; Kelly, CN; Casero, RA; Yokota, N; Porter, CW; Rabb, H; Soleimani, M
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