P. D. T. O’Connor - Publications, H-index & Citations

P. D. T. O’Connor

University of Auckland

22H指数

385论文数

3.3K被引数

收录论文 17

发表时间

Novel Linker Variants of Antileishmanial/Antitubercular 7-Substituted 2-Nitroimidazooxazines Offer Enhanced Solubility 抗利什曼/抗结核7-取代的2-硝基咪唑并恶嗪的新型接头变体提供了增强的溶解度

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2021-01-21

OAAI

Thompson, Andrew M.; O'Connor, Patrick D.; Yardley, Vanessa; Maes, Louis; Launay, Delphine; Braillard, Stephanie; Chatelain, Eric; Wan, Baojie; Franzblau, Scott G.; Ma, Zhenkun; Cooper, Christopher B.; Denny, William A.

Heteroaryl ether analogues of an antileishmanial 7-substituted 2-nitroimidazooxazine lead afford attenuated hERG risk: In vitro and in vivo appraisal

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2021-01-01

OAAI

Thompson, Andrew M.; O'Connor, Patrick D.; Marshall, Andrew J.; Yardley, Vanessa; Maes, Louis; Gupta, Suman; Launay, Delphine; Braillard, Stephanie; Chatelain, Eric; Wan, Baojie; Franzblau, Scott G.; Ma, Zhenkun; Cooper, Christopher B.; Denny, William A.

Re-evaluating pretomanid analogues for Chagas disease: Hit-to-lead studies reveal both in vitro and in vivo trypanocidal efficacy

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2020-12-01

OAAI

Thompson, Andrew M.; O'Connor, Patrick D.; Marshall, Andrew J.; Francisco, Amanda F.; Kelly, John M.; Riley, Jennifer; Read, Kevin D.; Perez, Catherine J.; Cornwall, Scott; Thompson, R. C. Andrew; Keenan, Martine; White, Karen L.; Charman, Susan A.; Zulfiqar, Bilal; Sykes, Melissa L.; Avery, Vicky M.; Chatelain, Eric; Denny, William A.

Inhibition of the Cytolytic Protein Perforin Prevents Rejection of Transplanted Bone Marrow Stem Cells in Vivo 抑制细胞溶解蛋白穿孔素可防止体内移植骨髓干细胞的排斥反应

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2019-09-18

PREAI

Spicer, Julie A.; Miller, Christian K.; O'Connor, Patrick D.; Jose, Jiney; Giddens, Anna C.; Jaiswal, Jagdish K.; Jamieson, Stephen M. F.; Bull, Matthew R.; Denny, William A.; Akhlaghi, Hedieh; Trapani, Joseph A.; Hill, Geoff R.; Chang, Karshing; Gartlan, Kate H.

Synthesis and Evaluation of Imidazo[1,2-a]pyridine Analogues of the ZSTK474 Class of Phosphatidylinositol 3-Kinase Inhibitors

CHEMISTRY-AN ASIAN JOURNAL

IF3.3

2019-03-12

PREAI

Gamage, Swarna A.; Spicer, Julie A.; Tsang, Kit Y.; O'Connor, Patrick D.; Flanagan, Jack U.; Lee, Woo-Jeong; Dickson, James M. J.; Shepherd, Peter R.; Denny, William A.; Rewcastle, Gordon W.

Development of (6R)-2-Nitro-644-(trifluoromethoxy)phenoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2018-02-20

OAAI

Thompson, Andrew M.; O'Connor, Patrick D.; Marshall, Andrew J.; Blaser, Adrian; Yardley, Vanessa; Maes, Louis; Gupta, Suman; Launay, Delphine; Braillard, Stephanie; Chatelain, Eric; Wan, Baojie; Franzblau, Scott G.; Ma, Zhenkun; Cooper, Christopher B.; Denny, William A.

Substituted arylsulphonamides as inhibitors of perforin-mediated lysis 取代的芳基磺酰胺作为穿孔素介导的裂解的抑制剂

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2017-09-01

OAAI

Spicer, Julie A.; Miller, Christian K.; O'Connor, Patrick D.; Jose, Jiney; Huttunen, Kristiina M.; Jaiswal, Jagdish K.; Denny, William A.; Akhlaghi, Hedieh; Browne, Kylie A.; Trapani, Joseph A.

7-Substituted 2-Nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazines: Novel Antitubercular Agents Lead to a New Preclinical Candidate for Visceral Leishmaniasis

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2017-05-11

OAAI

Thompson, Andrew M.; O'Connor, Patrick D.; Marshall, Andrew J.; Yardley, Vanessa; Maes, Louis; Gupta, Suman; Launay, Delphine; Braillard, Stephanie; Chatelain, Eric; Franzblau, Scott G.; Wan, Baojie; Wane, Yuehong; Ma, Zhenkun; Cooper, Christopher B.; Denny, William A.

Repositioning Antitubercular 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazoles for Neglected Tropical Diseases: Structure-Activity Studies on a Preclinical Candidate for Visceral Leishmaniasis

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2016-03-08

OAAI

Thompson, Andrew M.; O'Connor, Patrick D.; Blaser, Adrian; Yardley, Vanessa; Maes, Louis; Gupta, Suman; Launay, Delphine; Martin, Denis; Franzblau, Scott G.; Wan, Baojie; Wang, Yuehong; Ma, Zhenkun; Denny, William A.

Exploration of a Series of 5-Arylidene-2-thioxoimidazolidin-4-ones as Inhibitors of the Cytolytic Protein Perforin

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2013-11-19

OAAI

Spicer, Julie A.; Lena, Gersande; Lyons, Dani M.; Huttunen, Kristiina M.; Miller, Christian K.; O'Connor, Patrick D.; Bull, Matthew; Helsby, Nuala; Jamieson, Stephen M. F.; Denny, William A.; Ciccone, Annette; Browne, Kylie A.; Lopez, Jamie A.; Rudd-Schmidt, Jesse; Voskoboinik, Ilia; Trapani, Joseph A.

Discovery of pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2012-01-01

PREAI

Kendall, Jackie D.; O'Connor, Patrick D.; Marshall, Andrew J.; Frederick, Raphael; Marshall, Elaine S.; Lill, Claire L.; Lee, Woo-Jeong; Kolekar, Sharada; Chao, Mindy; Malik, Alisha; Yu, Shuqiao; Chaussade, Claire; Buchanan, Christina; Rewcastle, Gordon W.; Baguley, Bruce C.; Flanagan, Jack U.; Jamieson, Stephen M. F.; Denny, William A.; Shepherd, Peter R.

Appraisals of pain from controlled stimuli: Relevance to quantitative sensory testing

BRITISH JOURNAL OF HEALTH PSYCHOLOGY

IF2.5

2010-12-24

PREAI

Dannecker, Erin A.; Price, Donald D.; O'Connor, Patrick D.; Robinson, Michael E.

Synthesis and Reactivity of β-Methoxymethyl Enecarbamates

JOURNAL OF ORGANIC CHEMISTRY

IF3.6

2009-10-16

PREAI

O'Connor, Patrick D.; Marino, Michael G.; Gueret, Stephanie M.; Brimble, Margaret A.