未登录 Synthesis of a Complex and Highly Potent PCSK9 Inhibitor Kuethe, Jeffrey T.; Lee, Joshua; Thaisrivongs, David; Yasuda, Nobuyoshi; Pollack, Scott R.; Leone, Joseph; DaSilva, Jimmy; Biba, Mirlinda; Tsay, Fuh-Rong; Regalado, Erik L.; Qi, Ji; Li, Hongming; Dal Poggetto, Guilherme; Cohen, Ryan 分享 收藏
FusorSV: an algorithm for optimally combining data from multiple structural variation detection methods FusorSV: 一种用于优化组合来自多种结构变异检测方法的数据的算法 Becker, Timothy; Lee, Wan-Ping; Leone, Joseph; Zhu, Qihui; Zhang, Chengsheng; Liu, Silvia; Sargent, Jack; Shanker, Kritika; Mil-homens, Adam; Cerveira, Eliza; Ryan, Mallory; Cha, Jane; Navarro, Fabio C. P.; Galeev, Timur; Gerstein, Mark; Mills, Ryan E.; Shin, Dong-Guk; Lee, Charles; Malhotra, Ankit 分享 收藏
New reactions and processes for the efficient synthesis of a HCV NS5b prodrug Orr, Robert K.; Dunn, Jamie M. McCabe; Nolting, Andrew; Hyde, Alan M.; Ashley, Eric R.; Leone, Joseph; Sirota, Eric; Jurica, Jon A.; Gibson, Andrew; Wise, Christopher; Oliver, Steven; Ruck, Rebecca T. 分享 收藏
Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain Chobanian, Harry R.; Guo, Yan; Liu, Ping; Chioda, Marc D.; Fung, Selena; Lanza, Thomas J.; Chang, Linda; Bakshi, Raman K.; Dellureficio, James P.; Hong, Qingmei; McLaughlin, Mark; Belyk, Kevin M.; Krska, Shane W.; Makarewicz, Amanda K.; Martel, Elliot J.; Leone, Joseph F.; Frey, Lisa; Karanam, Bindhu; Madeira, Maria; Alvaro, Raul; Shuman, Joyce; Salituro, Gino; Terebetski, Jenna L.; Jochnowitz, Nina; Mistry, Shruti; McGowan, Erin; Hajdu, Richard; Rosenbach, Mark; Abbadie, Catherine; Alexander, Jessica P.; Shiao, Lin-Lin; Sullivan, Kathleen M.; Nargund, Ravi P.; Wyvratt, Matthew J.; Lin, Linus S.; DeVita, Robert J. 分享 收藏
Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase MK-3168的发现: 用于脑脂肪酸酰胺水解酶成像的PET示踪剂 Liu, Ping; Hamill, Terence G.; Chioda, Marc; Chobanian, Harry; Fung, Selena; Guo, Yan; Chang, Linda; Bakshi, Raman; Hong, Qingmei; Dellureficio, James; Lin, Linus S.; Abbadie, Catherine; Alexander, Jessica; Jin, Hong; Mandala, Suzanne; Shiao, Lin-Lin; Li, Wenping; Sanabria, Sandra; Williams, David; Zeng, Zhizhen; Hajdu, Richard; Jochnowitz, Nina; Rosenbach, Mark; Karanam, Bindhu; Madeira, Maria; Salituro, Gino; Powell, Joyce; Xu, Ling; Terebetsld, Jenna L.; Leone, Joseph F.; Miller, Patricia; Cook, Jacquelynn; Holahan, Marie; Joshi, Aniket; O'Malley, Stacey; Purcell, Mona; Posavec, Diane; Chen, Tsing-Bau; Riffe, Kerry; Williams, Mangay; Hargreaves, Richard; Sullivan, Kathleen A.; Nargund, Ravi P.; DeVitat, Robert J. 分享 收藏
Cyclic phosphoramidates as prodrugs of 2′-C-methylcytidine Meppen, Malte; Pacini, Barbara; Bazzo, Renzo; Koch, Uwe; Leone, Joseph F.; Koeplinger, Kenneth A.; Rowley, Michael; Altamura, Sergio; Di Marco, Annalise; Fiore, Fabrizio; Giuliano, Claudio; Gonzalez-Paz, Odalys; Laufer, Ralph; Pucci, Vincenzo; Narjes, Frank; Gardelli, Cristina 分享 收藏
Phosphoramidate Prodrugs of 2′-C-Methylcytidine for Therapy of Hepatitis C Virus Infection Gardelli, Cristina; Attenni, Barbara; Donghi, Monica; Meppen, Malte; Pacini, Barbara; Harper, Steven; Di Marco, Annalise; Fiore, Fabrizio; Giuliano, Claudio; Pucci, Vincenzo; Laufer, Ralph; Gennari, Nadia; Marcucci, Isabella; Leone, Joseph F.; Olsen, David B.; MacCoss, Malcolm; Rowley, Michael; Narjes, Frank 分享 收藏
Madin-darby canine kidney II cells:: A pharmacologically validated system for NPC1L1-mediated cholesterol uptake Weinglass, Adam B.; Koehler, Martin G.; Nketiah, Emmanuel O.; Liu, Jessica; Schmalhofer, William; Thomas, Anu; Williams, Brande; Beers, Lindsey; Smith, Lauren; Hafey, Mike; Bleasby, Kelly; Leone, Joseph; Tang, Yui Sing; Braun, Matthew; Ujjainwalla, Feroze; McCann, Margaret E.; Kaczorowski, Gregory J.; Garcia, Maria L. 分享 收藏
Synthesis and HCV inhibitory properties of 9-deaza- and 7,9-dideaza-7-oxa-2′-C-methyladenosine Butora, Gabor; Olsen, David B.; Carroll, Steven S.; McMasters, Daniel R.; Schmitt, Christoph; Leone, Joseph F.; Stahlhut, Mark; Burlein, Christine; MacCoss, Malcolm 分享 收藏
(2S, 3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl4-oxo-2-(4-[1,2,4]triazolo[1,5-a]pyridin-6-ylphenyl)butanamide:: A selective α-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes Edmondson, Scott D.; Mastracchio, Anthony; Mathvink, Robert J.; He, Jiafang; Harper, Bart; Park, You-Jung; Beconi, Maria; Di Salvo, Jerry; Eiermann, George J.; He, Huaibing; Leiting, Barbara; Leone, Joseph F.; Levorse, Dorothy A.; Lyons, Kathryn; Patel, Reshma A.; Patel, Sangita B.; Petrov, Aleksandr; Scapin, Giovanna; Shang, Jackie; Roy, Ranabir Sinha; Smith, Aaron; Wu, Joseph K.; Xu, Shiyao; Zhu, Bing; Thornberry, Nancy A.; Weber, Ann E. 分享 收藏
Structure-activity relationship of heterobase-modified 2′-C-methyl ribonucleosides as inhibitors of hepatitis C virus RNA replication Eldrup, AB; Prhavc, M; Brooks, J; Bhat, B; Prakash, TP; Song, QL; Bera, S; Bhat, N; Dande, P; Cook, PD; Bennett, CF; Carroll, SS; Ball, RG; Bosserman, M; Burlein, C; Colwell, LF; Fay, JF; Flores, OA; Getty, K; LaFemina, RL; Leone, J; MacCoss, M; McMasters, DR; Tomassini, JE; Von Langen, D; Wolanski, B; Olsen, DB 分享 收藏
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