未登录Enhanced Inhibition of ERK Signaling by a Novel Allosteric MEK Inhibitor, CH5126766, That Suppresses Feedback Reactivation of RAF Activity
Ishii, Nobuya; Harada, Naoki; Joseph, Eric W.; Ohara, Kazuhiro; Miura, Takaaki; Sakamoto, Hiroshi; Matsuda, Yutaka; Tomii, Yasushi; Tachibana-Kondo, Yukako; Iikura, Hitoshi; Aoki, Toshihiro; Shimma, Nobuo; Arisawa, Mikio; Sowa, Yoshihiro; Poulikakos, Poulikos I.; Rosen, Neal; Aoki, Yuko; Sakai, Toshiyuki .png)
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收藏An orally available, small-molecule interferon inhibits viral replicationKonishi, Hideyuki; Okamoto, Koichi; Ohmori, Yusuke; Yoshino, Hitoshi; Ohmori, Hiroshi; Ashihara, Motooki; Hirata, Yuichi; Ohta, Atsunori; Sakamoto, Hiroshi; Hada, Natsuko; Katsume, Asao; Kohara, Michinori; Morikawa, Kazumi; Tsukuda, Takuo; Shimma, Nobuo; Foster, Graham R.; Alazawi, William; Aoki, Yuko; Arisawa, Mikio; Sudoh, Masayuki 分享 收藏 Targeting microtubule-associated protein 4 with novel small molecule CH4938056 confers antitumor activity under quasi in vivo conditions and in xenograft modelsKondoh, Osamu; Saito, Hidemi; Nakanishi, Yoshito; Tsukaguchi, Toshiyuki; Nagano, Kohji; Inomata, Noriyuki; Sakata, Kiyoaki; Fujii, Toshihiko; Satoh, Yasuko; Hattori, Kazuo; Niizuma, Satoshi; Koyama, Kohei; Okada, Takehiro; Minoshima, Yukinori; Kawashima, Toshiyuki; Kitamura, Toshio; Tsukuda, Takuo; Nobuo, Shimma; Arisawa, Mikio; Ishii, Nobuya; Aoki, Yuko 分享 收藏 CH5126766 is a novel allosteric inhibitor of MEK that prevents its phosphorylation by RAFIshii, Nobuya; Harada, Naoki; Sakamoto, Hiroshi; Matsuda, Yutaka; Tomii, Yasushi; Tachibana-Kondo, Yukako; Miura, Takaaki; Ohara, Kazuhiro; Iikura, Hitoshi; Aoki, Toshihiro; Shimma, Nobuo; Arisawa, Mikio; Joseph, Eric; Poulikakos, Poulikos; Sowa, Yoshihiro; Rosen, Neal; Aoki, Yuko; Sakai, Toshiyuki 分享 收藏 Host sphingolipid biosynthesis as a target for hepatitis C virus therapySakamoto, H; Okamoto, K; Aoki, M; Kato, H; Katsume, A; Ohta, A; Tsukuda, T; Shimma, N; Aoki, Y; Arisawa, M; Kohara, M; Sudoh, M 分享 收藏 分享 收藏 Mechanisms of fluconazole resistance in Candida albicans isolates from Japanese AIDS patientsMaebashi, K; Niimi, M; Kudoh, M; Fischer, FJ; Makimura, K; Niimi, K; Piper, RJ; Uchida, K; Arisawa, M; Cannon, RD; Yamaguchi, H 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 
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