未登录COMPOUND 2 is a first-in-class small molecule cGAMP competitive oral STING antagonist that reduces neuroinflammation in mouse models
Banerjee, Monali; Shrivastava, Ritesh; Middya, Sandip; Basu, Sourav; Middya, Anindita; Shinde, Vaibhav; Ghosh, Rajib; Padaliya, Manisha; Bano, Shahnaj; Mansuri, Rubeena; Sharma, Priti; Roy, Sneha; Soram, Thanilsana; Yadav, Dharmendra; Puniya, Kavita; Gautam, Anuj; Pryde, David .png)
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收藏COMPOUND 1 is a first-in-class small molecule cGAMP competitive oral STING antagonist that reduces lung inflammation and fibrosis in chronic bleomycin and silica mouse modelsBanerjee, Monali; Middya, Sandip; Shrivastava, Ritesh; Basu, Sourav; Ghosh, Rajib; Middya, Anindita; Mane, Nagaswamy; Sharma, Priti; Rawat, Nidhi; Soram, Thanilsana; Mansuri, Rubeena; Yadav, Dharmendra; Gautam, Anuj; Shinde, Vaibhav; Padaliya, Manisha; Bano, Shahnaj; Roy, Sneha 分享 收藏 The allosteric STING agonist CRD3874 is systemically tolerated demonstrates systemic tolerabilityBanerjee, Monali; Middya, Sandip; Shrivastava, Ritesh; Middya, Anindita; Mane, Nagaswamy; Rawat, Nidhi; Soram, Thanilsana; Chakraborty, Debjani; Ghosh, Rajib; Mansuri, Rubeena R.; Yadav, Dharmendra; Gautam, Anuj; Singh, Anuj; Puniya, Kavita; Pryde, David; Basu, Sourav; Sonego, Fabiane; Martin, Gaelle H.; Thiam, Kader; Surya, Arjun 分享 收藏 Discovery of CRD1601, a potent and selective HPK1 inhibitor with robust in vivo anti-cancer activityBanerjee, Monali; Shrivastava, Ritesh; Pryde, David; Middya, Sandip; Debnath, Sabyasachi; Middya, Anindita; Yadav, Dharmendra; Rawat, Nidhi; Ghosh, Rajib; Padaliya, Manisha; Basu, Sourav; Surya, Arjun 分享 收藏 分享 收藏 分享 收藏 分享 收藏 CRD5500: A versatile small molecule STING agonist amenable to bioconjugation as an ADCBanerjee, Monali; Basu, Sourav; Middya, Sandip; Shrivastava, Ritesh; Ghosh, Rajib; Pryde, David C.; Yadav, Dharmendra; Bhattacharya, Gopal; Soram, Thanilsana; Puniya, Kavita; Raina, Ritika; Kadam, Vijay; Garai, Sujay; Sharma, Priti; Singh, Anuj; Shinde, Vaibhav; Rawat, Nidhi; Middya, Anindita; Sinha, Arghyotri; Chandel, Sunita; Narisipuram, Ganesh; Chatterjee, Abhisek; Mane, Nagaswamy; Surya, Arjun 分享 收藏 Small molecule ACSS2 inhibitors target acetate metabolizing tumor cells in hypoxic conditionsBanerjee, Monali; Basu, Sourav; Chakraborty, Debjani; Shrivastava, Ritesh; Middya, Sandip; Ghosh, Rajib; Yadav, Dharmendra; Sinha, Arghyotri; Das, Avratanu; Pandit, Navin; Naiya, Mohinder; Debnath, Sabyasachi; Dey, Sangeeta; Dasgupta, Debottam; Das, Nirmal; Singh, Anuj; Sarkar, Dipayan; Sarkar, Sukanya; Narasipuram, Ganesh; Mane, Nagaswami; Singhal, Nicky; Rawat, Nidhi; Middya, Anindita; Surya, Arjun 分享 收藏 RG70099: A novel, highly potent dual IDO1/TDO inhibitor to reverse metabolic suppression of immune cells in the tumor micro-environmentGyulveszi, Gabor; Fischer, Christine; Mirolo, Massimiliano; Stern, Martin; Green, Luke; Ceppi, Maurizio; Wang, Haiyan; Burgi, Beatrice; Staempfli, Andreas; Muster, Wolfgang; van Waterschoot, Robert; Gloge, Andreas; Sade, Hadassah; Klaman, Irina; Hoelzlvimmer, Gabriele; Surya, Arjun; Banerjee, Monali; Shrivastava, Ritesh; Middya, Sandip; Yadav, Dharmendra; Basu, Sourav; Acuna, Gonzalo 分享 收藏 Dihydrochelerythrine and its derivatives: Synthesis and their application as potential G-quadruplex DNA stabilizing agentsMalhotra, Rajesh; Rarhi, Chhanda; Diveshkumar, K. V.; Barik, Rajib; D'cunha, Ruhee; Dhar, Pranab; Kundu, Mrinalkanti; Chattopadhyay, Subrata; Roy, Subho; Basu, Sourav; Pradeepkumar, P. I.; Hajra, Saumen 分享 收藏 Rhodium-Catalyzed Enantioselective Conjugate Addition of Arylboronic Acids to DihydronitronaphthalenesHajra, Saumen; Ghosh, Rajib; Chakrabarti, Sagar; Ghosh, Amit; Dutta, Swarup; Dey, Tushar K.; Malhotra, Rajesh; Asijaa, Sonika; Roy, Subho; Dutta, Shantanu; Basu, Sourav 分享 收藏 分享 收藏 
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