未登录 Sensitivity of oncogenic KRAS-expressing cells to CDK9 inhibition identified by a phenotypic compound screen 通过表型化合物筛选鉴定的致癌KRAS表达细胞对CDK9抑制的敏感性 Lai, Lick P.; Brel, Viviane; Sharma, Kanika; Frappier, Julia; Le-Henanf, Nadia; Vivet, Bertrand; Muzet, Nicolas; Schell, Emilie; Morales, Renaud; Rooney, Eamonn; Holderfield, Matthew; Lacroix, Frederic; Englaro, Walter; Marcireau, Christophe; Debussche, Laurent; Nissley, Dwight, V; Mccormick, Frank 分享 收藏
Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule Deng, Gejing; Shen, Junqing; Yin, Ming; McManus, Jessica; Mathieu, Magali; Gee, Patricia; He, Timothy; Shi, Chaomei; Bedel, Olivier; McLean, Larry R.; Le-Strat, Frank; Zhang, Ying; Marquette, Jean-Pierre; Gao, Qiang; Zhang, Bailin; Rak, Alexey; Hoffmann, Dietmar; Rooney, Eamonn; Vassort, Aurelie; Englaro, Walter; Li, Yi; Patel, Vinod; Adrian, Francisco; Gross, Stefan; Wiederschain, Dmitri; Cheng, Hong; Licht, Stuart 分享 收藏
Selective inhibition of mutant IDH1 via small molecule binding to the dimer interface Deng, Gejing; Licht, Stuart; Shen, Junqing; Yin, Ming; McManus, Jessica; Gee, Patricia; He, Tim; Gao, Giang; Zhang, Bailin; Mathieu, Magali; Rak, Alexey; Bedel, Olivier; Shi, Chaomei; Gross, Stefan; Hoffmann, Dietmar; Rooney, Eamonn; Vassort, Aurelie; Englaro, Walter; Li, Yi; Wiederschain, Dmitri; Patel, Vinod; Adrian, Francisco; Cheng, Hong 分享 收藏
High-resolution dose-response screening using droplet-based microfluidics Miller, Oliver J.; El Harrak, Abdeslam; Mangeat, Thomas; Baret, Jean-Christophe; Frenz, Lucas; El Debs, Bachir; Mayot, Estelle; Samuels, Michael L.; Rooney, Eamonn K.; Dieu, Pierre; Galvan, Martin; Link, Darren R.; Griffiths, Andrew D. 分享 收藏
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