未登录 Identification of CD73 and A2AR/CD73 small molecule inhibitors for cancer immunotherapy as single agents or in combination with Immune-checkpoint therapies Fons, Pierre; Bell, Andrew; Esquerre, Michael; Versluys, Stephanie; Bertrand, Florie; Schreyer, Adrian; Hopkins-Navratilova, Iva; Hernani, Leonardo-Silvestre; Bergeaud, Celia; Poussereau-Pomie, Celine; Marchand, Ghislaine; Robinson, Sean; Culurgioni, Simone; Cox, Richard; Besnard, Jeremy; Payne, Andrew; Ray, Peter; Pelissier, Emilie; Paillasse, Michael; Lisztwan, Joanna; Johnstone, Craig; Whittaker, Mark; Hopkins, Andrew 分享 收藏
EVOEXS21546 is a novel non-brain penetrant A2AR inhibitor for cancer immunotherapy with accelerated drug development Fons, Pierre; Bell, Andy; Esquerre, Michael; Versluys, Stephanie; Bertrand, Florie; Hopkins-Navratilova, Iva; Robinson, Sean; Visentin, Virgile; Schreyer, Adrian; Cox, Richard; Mirey, Emilie; Pelissier, Emilie; Bergeaud, Celia; Culurgioni, Simone; Besnard, Jeremy; Payne, Andrew; Menegotto, Jerome; Machet, Frederic; Poussereau-Pomie, Celine; Cogo, Eric; Paillasse, Michael; Ferigo, Federica; Pagliarusco, Sabrina; Lisztwan, Joanna; Whittaker, Mark; Johnstone, Craig; Hopkins, Andrew 分享 收藏
Identification of a novel non-brain penetrant A2AR inhibitor and proof-of-concept of CD73 and A2AR/CD73 small-molecule inhibitors for cancer immunotherapy Fons, Pierre; Bell, Andy; Esquerre, Michael; Versluys, Stephanie; Bertrand, Florie; Poussereau-Pomie, Celine; Schreyer, Adrian; Cox, Richard; Besnard, Jeremy; Paillasse, Michael; Swindells, Mark; Lisztwan, Joanna; Johnstone, Craig; Whittaker, Mark; Hopkins, Andrew 分享 收藏
Targeting the adenosine immunosuppressive pathway for cancer immunotherapy with small molecule agents Fons, Pierre; Esquerre, Michael; Versluys, Stephanie; Mambrini, Gigliola; Paillasse, Michael; Bell, Andy; Schreyer, Adrian; Cox, Richard; Bickerton, Richard; Lisztwan, Joanna; Whittaker, Mark; Bono, Francoise; Johnstone, Craig; Hopkins, Andrew 分享 收藏
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Making medicinal chemistry more effective-application of Lean Sigma to improve processes, speed and quality Andersson, Shalini; Armstrong, Alan; Bjore, Annika; Bowker, Sue; Chapman, Steve; Davies, Rob; Donald, Craig; Egner, Bryan; Elebring, Thomas; Holmqvist, Sara; Inghardt, Tord; Johannesson, Petra; Johansson, Magnus; Johnstone, Craig; Kemmitt, Paul; Kihlberg, Jan; Korsgren, Pernilla; Lemurell, Malin; Moore, Jane; Pettersson, Jonas A.; Pointon, Helen; Ponten, Fritiof; Schofield, Paul; Selmi, Nidhal; Whittamore, Paul 分享 收藏
Predictive blood glucose lowering efficacy by Glucokinase activators in high fat fed female Zucker rats Coope, G. J.; Atkinson, A. M.; Allott, C.; McKerrecher, D.; Johnstone, C.; Pike, K. G.; Holme, P. C.; Vertigan, H.; Gill, D.; Coghlan, M. P.; Leighton, B. 分享 收藏
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Novel 4-anilinoquinazolines with C-7 basic side chains:: Design and structure activity relationship of a series of potent, orally active, VEGF receptor tyrosine kinase inhibitors Hennequin, LF; Stokes, ESE; Thomas, AP; Johnstone, C; Plé, PA; Ogilvie, DJ; Dukes, M; Wedge, SR; Kendrew, J; Curwen, JO 分享 收藏
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Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors Hennequin, LF; Thomas, AP; Johnstone, C; Stokes, ESE; Plé, PA; Lohmann, JJM; Ogilvie, DJ; Dukes, M; Wedge, SR; Curwen, JO; Kendrew, J; Lambert-van der Brempt, C 分享 收藏
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