Nina Mohell - Publications, H-index & Citations

Nina Mohell

Karolinska Institutet

29H指数

109论文数

2.7K被引数

收录论文 24

发表时间

Strong synergy with APR-246 and DNA-damaging drugs in primary cancer cells from patients with TP53 mutant High-Grade Serous ovarian cancer

JOURNAL OF OVARIAN RESEARCH

IF4.2

2016-05-14

OAAI

Fransson, Asa; Glaessgen, Daria; Alfredsson, Jessica; Wiman, Klas G.; Bajalica-Lagercrantz, Svetlana; Mohell, Nina

Preliminary results from PiSARRO, a phase Ib/II study of APR-246, a mutant p53 reactivating small molecule, in combination with standard chemotherapy in platinum-sensitive ovarian cancer

CANCER RESEARCH

IF16.6

2015-08-01

OAAI

von Euler, Mikael; Wiman, Klas G.; Gabra, Hani; Brenton, James D.; Basu, Bristi; Vergote, Ignace; Gourley, Charlie; Smith, Austin; Alfredsson, Jessica; Mohelll, Nina; Green, John A.

Strong synergy with APR-246 and DNA-damaging drugs in primary ovarian cancer cells

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Fransson, Asa; Glaessgen, Daria; Alfredsson, Jessica; Wiman, Klas G.; Lagercrantz, Svetlana Bajalica; Mohelll, Nina

APR-246 overcomes resistance to cisplatin and doxorubicin in ovarian cancer cells APR-246克服了卵巢癌细胞对顺铂和阿霉素的耐药性

CELL DEATH & DISEASE

IF9.6

2015-06-18

159

OAAI

Mohell, N.; Alfredsson, J.; Fransson, A.; Uustalu, M.; Bystrom, S.; Gullbo, J.; Hallberg, A.; Bykov, V. J. N.; Bjorklund, U.; Wiman, K. G.

APR-246, a clinical-stage mutant p53-reactivating compound, resensitizes ovarian cancer cells to platinum compounds and doxorubicin

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Mohell, Nina; Alfredsson, Jessica; Fransson, Asa; Bykov, Vladimir; von Euler, Mikael; Wiman, Klas; Bjorklund, Ulf

Strong synergistic effects with cisplatin and APR-246, a novel compound reactivating mutant p53, in ovarian cancer cell lines and primary cells from patients

CANCER RESEARCH

IF16.6

2013-04-01

PREAI

Mohell, Nina; Alfredsson, Jessica; Uustalu, Maria; Fransson, Asa; Bykov, Vladimir J. N.; Wiman, Klas G.; Bjorklund, Ulf

Identification of novel selective V2 receptor non-peptide agonists

BIOCHEMICAL PHARMACOLOGY

IF5.6

2008-10-01

PREAI

Del Tredici, Andria L.; Vanover, Kim E.; Knapp, Anne E.; Bertozzi, Sine M.; Nash, Norman R.; Burstein, Ethan S.; Lameh, Jelveh; Currier, Erika A.; Davis, Robert E.; Brann, Mark R.; Mohell, Nina; Olsson, Roger; Piu, Fabrice

PRECLINICAL FINDINGS WITH NEW ANTIPSYCHOTIC AGENTS - WHAT MAKES THEM ATYPICAL

Acta Psychiatrica Scandinavica

IF5

2007-08-23

PREAI

JACKSON, DM; RYAN, C; EVENDEN, J; MOHELL, N

Neuropeptide Y-family receptors Y6 and Y7 in chicken -: Cloning, pharmacological characterization, tissue distribution and conserved synteny with human chromosome region

FEBS JOURNAL

IF4.2

2006-04-26

OAAI

Bromée, T; Sjödin, P; Fredriksson, R; Boswell, T; Larsson, TA; Salaneck, E; Zoorob, R; Mohell, N; Larhammar, D

Re-evaluation of receptor-ligand interactions of the human neuropeptide Y receptor Y1:: a site-directed mutagenesis study

BIOCHEMICAL JOURNAL

IF4.3

2005-12-12

OAAI

Sjödin, P; Holmberg, SKS; Åkerberg, H; Berglund, MM; Mohell, N; Larhammar, D

Design, synthesis and evaluation of a PLG tripeptidomimetic based on a pyridine scaffold

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2004-11-18

PREAI

Saitton, S; Del Tredici, AL; Mohell, N; Vollinga, RC; Boström, D; Kihlberg, J; Luthman, K

Inhibitory effects of halothane on the thermogenic pathway in brown adipocytes:: localization to adenylyl cyclase and mitochondrial fatty acid oxidation

BIOCHEMICAL PHARMACOLOGY

IF5.6

2004-08-01

PREAI

Ohlson, KBE; Shabalina, IG; Lennström, K; Backlund, EC; Mohell, N; Bronnikov, GE; Lindahl, SGE; Cannon, B; Nedergaard, J

The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine

PSYCHOPHARMACOLOGY

IF3.3

2004-07-16

219

PREAI

Weiner, DM; Meltzer, HY; Veinbergs, I; Donohue, EM; Spalding, TA; Smith, TT; Mohell, N; Harvey, SC; Lameh, J; Nash, N; Vanover, KE; Olsson, R; Jayathilake, K; Lee, M; Levey, AI; Hacksell, U; Burstein, ES; Davis, RE; Brann, M

Novel 2-aminotetralin and 3-AminoChroman derivatives as selective serotonin 5-HT7 receptor agonists and antagonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2004-06-29

PREAI

Holmberg, P; Sohn, D; Leideborg, R; Caldirola, P; Zlatoidsky, P; Hanson, S; Mohell, N; Rosqvist, S; Nordvall, G; Johansson, AM; Johansson, R

Pharmacology of polymorphic variants of the human 5-HT1A receptor

BIOCHEMICAL PHARMACOLOGY

IF5.6

2004-02-01

PREAI

Del Tredici, AL; Schiffer, HH; Burstein, ES; Lameh, J; Mohell, N; Hacksell, U; Brann, MR; Weiner, DM

Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chloropheny)-3-(2-(dimethylamino)ethyl)isochroman-1-one (AC-7954)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2002-10-09

PREAI

Croston, GE; Olsson, R; Currier, EA; Burstein, ES; Weiner, D; Nash, N; Severance, D; Allenmark, SG; Thunberg, L; Ma, JN; Mohell, N; O'Dowd, B; Brann, MR; Hacksell, U

DERIVATIVES OF CIS-2-AMINO-8-HYDROXY-1-METHYLTETRALIN - MIXED 5-HT(1A)-RECEPTOR AGONISTS AND DOPAMINE D-2-RECEPTOR ANTAGONISTS

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2002-05-01

PREAI

LIU, Y; YU, H; MOHELL, N; NORDVALL, G; LEWANDER, T; HACKSELL, U

Site-directed mutagenesis of the 5-HT1B receptor increases the affinity of 5-HT for the agonist low-affinity conformation and reduces the intrinsic activity of 5-HT 5-HT1B受体的定点诱变增加了5-HT对激动剂低亲和力构象的亲和力，并降低了5-HT的内在活性

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2001-06-01

PREAI

Grånäs, C; Nordquist, J; Mohell, N; Larhammar, D

Synthesis of novel 5-substituted 3-amino-3,4-dihydro-2H-1-benzopyran derivatives and their interactions with the 5-HT1A receptor

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2000-06-30

PREAI

Hammarberg, E; Nordvall, G; Leideborg, R; Nylöf, M; Hanson, S; Johansson, L; Thorberg, SO; Tolf, BR; Jerning, E; Svantesson, GT; Mohell, N; Ahlgren, C; Westlind-Danielsson, A; Csöregh, I; Johansson, R

Structural analogues of 5-OMe-BPAT:: Synthesis and interactions with dopamine D2, D3, and serotonin 5-HT1A receptors

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

1999-06-01

PREAI

Homan, EJ; Kroodsma, E; Copinga, S; Unelius, L; Mohell, N; Wikström, HV; Grol, CJ

研究方向