未登录 Safety, Pharmacokinetics, and Activity of AT-752, a Novel Nucleotide Prodrug with Pan-Serotype Activity against Dengue Virus: A Phase 2, Randomized, Double-Blind Study Horga, Arantxa; Teixeira, Mauro M.; Borthakur, Swapnav; Lynch, Shannan; Chin, Janice; Ishak, Laura; Zhou, Xiao-Jian; Pietropaolo, Keith; Belanger, Bruce; Lei, Yang; Huang, Qi; Hammond, Janet 分享 收藏
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Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example Boehm, Markus; Hepworth, David; Loria, Paula M.; Norquay, Lisa D.; Filipski, Kevin J.; Chin, Janice E.; Cameron, Kimberly O.; Brenner, Martin; Bonnette, Peter; Cabral, Shawn; Conn, Edward; Ebner, David C.; Gautreau, Denise; Hadcock, John; Lee, Esther C. Y.; Mathiowetz, Alan M.; Morin, Michelle; Rogers, Lucy; Smith, Aaron; VanVolkenburg, Maria; Carpino, Philip A. 分享 收藏
Potent Histone Deacetylase Inhibitors Derived from 4-(Aminomethyl)-N-hydroxybenzamide with High Selectivity for the HDAC6 Isoform Blackburn, Christopher; Barrett, Cynthia; Chin, Janice; Garcia, Kris; Gigstad, Kenneth; Gould, Alexandra; Gutierrez, Juan; Harrison, Sean; Hoar, Kara; Lynch, Chrissie; Rowland, R. Scott; Tsu, Chris; Ringeling, John; Xu, He 分享 收藏
Identification of Tetrahydropyrido[4,3-d]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists 鉴定四氢吡啶并 [4，3-d] 嘧啶酰胺作为一类新的口服生物可利用的TGR5激动剂 Piotrowski, David W.; Futatsugi, Kentaro; Warmus, Joseph S.; Orr, Suvi T. M.; Freeman-Cook, Kevin D.; Londregan, Allyn T.; Wei, Liuqing; Jennings, Sandra M.; Herr, Michael; Coffey, Steven B.; Jiao, Wenhua; Storer, Gregory; Hepworth, David; Wang, Jian; Lavergne, Sophie Y.; Chin, Janice E.; Hadcock, John R.; Brenner, Martin B.; Wolford, Angela C.; Janssen, Ann M.; Roush, Nicole S.; Buxton, Joanne; Hinchey, Terri; Kalgutkar, Amit S.; Sharma, Raman; Flynn, Declan A. 分享 收藏
A Selective Cannabinoid-1 Receptor Antagonist, PF-95453, Reduces Body Weight and Body Fat to a Greater Extent than Pair-Fed Controls in Obese Monkeys Wagner, Janice D.; Zhang, Li; Kavanagh, Kylie; Ward, Gina M.; Chin, Janice E.; Hadcock, John R.; Auerbach, Bruce J.; Harwood, H. James, Jr. 分享 收藏
SYNTHESIS OF NOVEL 2,4-DIAMINOPYRROLO[2,3-D]PYRIMIDINES WITH ANTIOXIDANT, NEUROPROTECTIVE, AND ANTIASTHMA ACTIVITY BUNDY, GL; AYER, DE; BANITT, LS; BELONGA, KL; MIZSAK, SA; PALMER, JR; TUSTIN, JM; CHIN, JE; HALL, ED; LINSEMAN, KL; RICHARDS, IM; SCHERCH, HM; SUN, FF; YONKERS, PA; LARSON, PG; LIN, JM; PADBURY, GE; AARON, CS; MAYO, JK 分享 收藏
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